Results 271 to 280 of about 156,159 (310)
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Matrix Metalloproteinase-9 and Autoimmune Diseases

Journal of Clinical Immunology, 2006
Matrix metalloproteinases (also named matrixin or MMPs) are a major group of enzymes that regulate cell-matrix composition by using zinc for their proteolytic activities. They are essential for various normal biological processes such as embryonic development, morphogenesis, reproduction tissue resorption, and remodeling. Metalloproteinases also play a
Maya, Ram   +2 more
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“Uncorking” of liposomes by matrix metalloproteinase-9

Chem. Commun., 2005
A triggered release methodology of liposomal contents via the enzyme MMP-9 is described.
Nihar R, Sarkar   +6 more
openaire   +2 more sources

The role of matrix metalloproteinase-9 in dementia

Neuroscience Letters, 2003
Neurofibrillary tangles and senile plaques, constituted of extracellular amyloid deposits (Abeta), are the two defining pathological hallmarks of Alzheimer's disease (AD). Inhibiting the synthesis or aggregation of Abeta or increasing its clearance may reduce the detrimental effects of this peptide and consequently improve cognitive functions in ...
Nicole, Helbecque   +3 more
openaire   +2 more sources

Comment on “Matrix Metalloproteinase-7 and Matrix Metalloproteinase-9 in Pediatric Multiple Sclerosis”

Pediatric Neurology, 2013
To the Editor: We read with interest the article by Unsal et al [1] indicating the levels of matrix metalloproteinasee9 (MMP-9), matrix metalloproteinase-7, and tissue inhibitor of metalloproteinase-1 (TIMP-1) in serum samples of children afflicted with multiple sclerosis (MS).
Hamid, Zahednasab   +2 more
openaire   +2 more sources

Matrix metalloproteinase-9 and matrix metalloproteinase-2 gene polymorphisms in multiple sclerosis

Journal of Neuroimmunology, 2008
We investigated the association of matrix metalloproteinase-9 (-1562C/T, +279R/Q) and matrix metalloproteinase-2 (-1575G/A, -1306C/T) gene polymorphisms with multiple sclerosis (MS) susceptibility, gender differences and disability in 244 patients and 132 healthy subjects.
Yvonne, Benesová   +7 more
openaire   +2 more sources

Matrix metalloproteinase-2 and Matrix metalloproteinase-9 in cholesteatoma and deep meatal skin

Clinical Otolaryngology and Allied Sciences, 1998
A qualitative and quantitative study of the presence of Matrix metalloproteinase-2 (MMP-2) and Matrix metalloproteinase-9 (MMP-9) in cholesteatoma was performed. Ten cholesteatoma and four deep meatal skin specimens were analysed for gelatinase activity at molecular weights corresponding to MMP-2 and MMP-9 using Sodium Dodecyl Sulphate Polyacrylamide ...
A R, Banerjee, R, James, A A, Narula
openaire   +2 more sources

Tissue levels of active matrix metalloproteinase-2 and -9 in colorectal cancer

open access: yesBritish Journal of Cancer, 2002
Item does not contain fulltextThe bioactivity of matrix metalloproteinases was studied in tissues from colorectal cancer patients by means of both quantitative gelatin zymography and a fluorometric activity assay.
Jeroen Degroot, T Hendriks
exaly   +2 more sources

Matrix metalloproteinases 2 and 9, and extracellular matrix in Kaposi's sarcoma

Dermatologic Therapy, 2010
Matrix metalloproteinases (MMPs) are associated with Kaposi's sarcoma (KS) tumorigenesis and may contribute to the mechanism of KS invasive growth. To date, only a few MMPs have been studied in KS lesions, and exactly which MMPs are involved in KS development and progression remains unanswered.
BONGIORNO, Maria Rita   +3 more
openaire   +3 more sources

Matrix metalloproteinase-9 and osteoporosis

2023
Introduction: Matrix metalloproteinases (MMPs) are a family of zinc-dependent proteolytic enzymes involved in the degradation of extracellular matrix (ECM) components. The overexpression and increased activity of MMPs is observed in many physiological and pathological processes, including estrogen deficiency osteoporosis.
Grigoryan, Armine V.   +4 more
openaire   +1 more source

Matrix Metalloproteinase-9 and Airway Remodeling in Asthma

Current Drug Target -Inflammation & Allergy, 2005
Airway remodeling is a major change responsible for irreversible asthmatic airflow restriction. The Th-2 cytokines-dominant eosinophilic inflammatory mechanism cannot fully explain the progressive subepithelial fibrosis and structural changes in the extracellular matrix (ECM).
Hiroyuki, Ohbayashi, Kaoru, Shimokata
openaire   +2 more sources

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