Results 41 to 50 of about 236,208 (216)

Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells [PDF]

, 2007
MMP-9 (matrix metalloproteinase 9) plays a critical role in tumour progression. Although the biochemical properties of the secreted form of proMMP-9 are well characterized, little is known about the function and activity of cell surface-associated proMMP-
Egea, Virginia, Jochum, Marianne, Mentele, Reinhard, Nagase, Hideaki, Pitsch, Thomas, Ries, Christian, Zahler, Stefan   +6 more
core   +1 more source

Matrix Metalloproteinase-9 () polymorphisms in patients with cutaneous malignant melanoma [PDF]

, 2007
Background Cutaneous Malignant Melanoma causes over 75% of skin cancer-related deaths, and it is clear that many factors may contribute to the outcome.
Javier Cotignola, Boris Reva, Nandita Mitra, Nicole Ishill, Shaokun Chuai, Ami Patel, Shivang Shah, Gretchen Vanderbeek, Daniel Coit, Klaus Busam, Allan Halpern, Alan Houghton, Chris Sander, Marianne Berwick, Irene Orlow, A Jemal, LJ McCawley, S Pasco, SC Liu, H Islekel, W Zhao, YG Shellman, JJ van den Oord, UB Hofmann, MD Corte, J Nikkola, S Zucker, K Jung, GS Makowski, PE Van den Steen, RC Millikan, J Gough, CD Bennett, M Ronaghi, M Franchina, PJ Oefner, I Orlow, PD Sasieni, EL Kaplan, L Excoffier, JH Zhao, DJ Schaid, DG Peters, S Shimajiri, PE Ferrand, B Bodey, J Nikkola, UB Hofmann, B Zhang, F Grieu, S Matsumura, E Chicoine, EM Schnaeker, Y Awakura   +53 more
core   +1 more source

Matrix metalloproteinase 9 polymorphism and outcome after myocardial infarction

Cardiogenetics, 2011
Matrix metalloproteinase 9 (MMP9) is functionally implicated in the process of infarct healing. Several genetic variation of the MMP9 gene have been described, among which the MMP9 Arg668Gln polymorphism.
Sophie Rodius, Guillermo Mulliert, Francisco Azuaje, Yvan Devaux, Daniel R. Wagner   +4 more
doaj   +1 more source

Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 Expression in Canine and Feline Meningioma [PDF]

Veterinary Pathology, 2009
Fifty-one meningiomas obtained from 28 dogs and 23 cats were selected for this study to investigate the immunohistochemical expression of matrix metalloproteinase (MMP)-2 and MMP-9 and to compare it to the reverse transcriptase subunit of human-telomerase, progesterone receptor expression, and the proliferative index of the tumors, expressed by Ki67 ...
M. T. Mandara, S. Pavone, MANDRIOLI, LUCIANA, BETTINI, GIULIANO, C. Falzone, M. Baroni   +5 more
openaire   +2 more sources

Angiotensin Type 2 Receptor Stimulation Ameliorates Left Ventricular Fibrosis and Dysfunction via Regulation of Tissue Inhibitor of Matrix Metalloproteinase 1/Matrix Metalloproteinase 9 Axis and Transforming Growth Factor β1 in the Rat Heart [PDF]

, 2014
Left ventricular (LV) remodeling is the main reason for the development of progressive cardiac dysfunction after myocardial infarction (MI). This study investigated whether stimulation of the angiotensin type 2 receptor is able to ameliorate
Dahlöf, Bjorn, Hallberg, Anders, Kaschina, Elena, Kintscher, Ulrich, Lauer, Dilyara, Sharkovska, Yuliya, Slavic, Svetlana, Sommerfeld, Manuela, Steckelings, Ulrike Muscha, Thöne-Reineke, Christa, Unger, Thomas   +10 more
core   +2 more sources

Asthma remodeling: The pathogenic role of matrix metalloproteinase-9

Egyptian Journal of Chest Disease and Tuberculosis, 2014
Background: Asthma is an airway inflammatory disease with functional and structural changes, leading to bronchial hyperresponsiveness and airflow obstruction.
Amgad A. Farhat, Ahmad S. Mohamad, Mohamad M. Shareef, Ghada Atef Attia, Manal A. Eid, Rehab W. Taha   +5 more
doaj   +1 more source

Matrix metalloproteinase 9 gene-MMP9-DNA methylation status in Turkish schizophrenia patients

Türk Biyokimya Dergisi, 2023
Schizophrenia is a neuropsychiatric disease caused by disorders in brain development due to genetic and environmental factors. The interactions and mechanisms of the two main etiological factors are not fully understood despite neurobiological, clinical ...
Karaaslan Ezgi, Kartalci Şükrü, Bağ Harika Gözde Gözükara, Acar Ceren   +3 more
doaj   +1 more source

Complex regulation of neutrophil-derived MMP-9 secretion in central nervous system tuberculosis. [PDF]

, 2017
BACKGROUND: Central nervous system tuberculosis (CNS-TB) may be fatal even with treatment. Neutrophils are the key mediators of TB immunopathology, and raised CSF matrix metalloproteinase-9 (MMP-9) which correlates to neutrophil count in CNS-TB is ...
Brilha, S, Elkington, PT, Friedland, JS, Ong, CWM, Pabisiak, PJ, Roncaroli, F, Singh, P   +6 more
core   +1 more source

Assessment of Matrix Metalloproteinases a Prognostic Indicator in Advanced Fibrotic Lung Disease: A Systematic Review

Pakistan Journal of Medicine and Dentistry
Background: Fibrotic lung diseases were seen to have devastating effects among patients globally. Matrix metalloproteinases (MMP) including MMP-7, MMP-9, and MMP-1 have become promising biomarkers for idiopathic pulmonary fibrosis (IPF), and other ...
Mehvish Aqil, Saif Ur Rahman, Muhammad Zeeshan Aslam, Mostafa Ahmed Abdellah Ahmed, Ammar Ahmed, Sidra Javaid, Ehsan Ul Haq   +6 more
doaj   +1 more source

The Role of MMP-9 and MMP-9 Inhibition in Different Types of Thyroid Carcinoma

Molecules, 2023
Matrix metalloproteinase-9 (MMP-9), one of the most investigated and studied biomarkers of the MMPs family, is a zinc-dependent proteolytic metalloenzyme whose primary function is degrading the extracellular matrix (ECM).
Zhenshengnan Li, Jia Wei, Bowen Chen, Yaoqi Wang, Shuai Yang, Kehui Wu, Xianying Meng   +6 more
doaj   +1 more source