Results 21 to 30 of about 156,159 (310)

Identification of a novel 82 kDa proMMP-9 species associated with the surface of leukaemic cells [PDF]

, 2007
MMP-9 (matrix metalloproteinase 9) plays a critical role in tumour progression. Although the biochemical properties of the secreted form of proMMP-9 are well characterized, little is known about the function and activity of cell surface-associated proMMP-
Mentele, Reinhard, Egea, Virginia, Jochum, Marianne, Ries, Christian, Zahler, Stefan, Nagase, Hideaki, Pitsch, Thomas   +6 more
core   +1 more source

A circular RNA derived from MMP9 facilitates oral squamous cell carcinoma metastasis through regulation of MMP9 mRNA stability

Cell Transplantation, 2019
Emerging evidence demonstrates that dysregulation of circular RNA is linked to tumorigenesis and aggressive progression. However, its role in oral squamous cell carcinoma remains largely uncharacterized.
Bing Xia, Tao Hong, Xin He, Xinlan Hu, Yongbo Gao   +4 more
doaj   +1 more source

MMPs Regulate Neuronal Substance P After a Painful Equibiaxial Stretch in a Co-Culture Collagen Gel Model Simulating Injury of an Innervated Ligament

Frontiers in Mechanical Engineering, 2022
Chronic joint pain is a major health problem that can result from abnormal loading of the innervated ligamentous capsule that surrounds synovial joints.
Meagan E. Ita, Beth A. Winkelstein, Beth A. Winkelstein   +2 more
doaj   +1 more source

Matrix Metalloproteinase-3 but Not Matrix Metalloproteinase-9, Implicated in the Manifestation of Chronic Periodontitis

Reports of Biochemistry and Molecular Biology, 2023
Periodontal disease is an inflammatory condition affecting the tooth's supporting tissues, resulting in gradual loss of periodontal ligament (PDL), alveolar bone, and gum resorption. Neutrophil and monocyte/macrophage, destructive proteases like matrix metalloproteinase (MMP)-3 and MMP-9 play pivotal roles in such lesions in periodontitis.
Pouyan, Razavi, Seyed Abdolrahim, Rezaee, Salehe, Akhondian, Nastaran, Asgari, Kazem, Fatemi, Farnaz, Mohajertehran   +5 more
openaire   +2 more sources

Relationships between MMP-2, MMP-9, and ADAMDEC1 serum and tissue levels in patients with colorectal cancer [PDF]

Annals of Coloproctology
Purpose Colorectal cancer (CRC) is the most common malignancy of the gastrointestinal system globally. Identifying specific gene expression patterns indicative of early-stage CRC could enable early diagnosis and rapid treatment initiation.
Zahra Mozooni, Kiana Khajeh Amiri, Nafiseh Golestani, Alireza Shahmohammadi, Sara Minaeian, Leyla Bahadorizadeh   +5 more
doaj   +1 more source

The Role of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Antibody-Induced Arthritis [PDF]

The Journal of Immunology, 2002
Abstract Matrix metalloproteinases (MMPs) are a large group of enzymes responsible for matrix degradation. Among them, the family of gelatinases (MMP-2/gelatinase A and MMP-9/gelatinase B) is overproduced in the joints of patients with rheumatoid arthritis.
Takeshi, Itoh, Hidetoshi, Matsuda, Masatoshi, Tanioka, Kenji, Kuwabara, Shigeyoshi, Itohara, Ryuji, Suzuki   +5 more
openaire   +2 more sources

Investigation of the relationship between matrix metalloproteinase-9 and tissue inhibitor of metalloproteinase with SARS CoV-2 infections

Journal of Advanced Biotechnology and Experimental Therapeutics, 2023
SARS-CoV-2 stands for severe acute respiratory syndrome coronavirus 2 which is the causative agent of spreading coronavirus disease 2019 that is known as COVID-19 pandemic, the disease leads to severe acute respiratory illness. Matrix metalloproteinases-
May K. Ismael, Lubna M. Rasuol, Yasir Basim Qaddoori   +2 more
doaj   +1 more source

Correlation of Matrix Metalloproteinases and Tissue Inhibitors of Matrix Metalloproteinase Expression in Ileal Carcinoids, Lymph Nodes and Liver Metastasis with Prognosis and Survival [PDF]

, 2009
Purpose: Ileal carcinoids are gut epithelial tumors originating from serotonin-containing enterochromaffin (EC) cells. Therapeutic options for effectively inhibiting the growth and spread of metastatic carcinoids are still limited.
Braun, Thomas, Besig, Sophie, Baur, Dorothee M., Prinz, Christian, Rad, Roland, Hoefler, Heinz, Höfler, Heinz, Voland, Petra, Perren, Aurel, Langer, Rupert   +9 more
core   +1 more source

Matrix metalloproteinase-9 as an independent predictor of recurrence after catheter ablation of atrial fibrillation

Journal of Education, Health and Sport, 2017
Objectives: In this study, the serum level of matrix metalloproteinase-9 was studied as an independent predictor of recurrence after catheter ablation of a persistent form of atrial fibrillation. Methods: The study included 46 patients with a persistent
A. V. Goryachiy, A. I. Gozhenko, E. M. Levchenko, V. V. Goriachyi, M. A. Kuznetsova, M. I. Arapu   +5 more
doaj   +3 more sources

Gender-dependent differences in plasma matrix metalloproteinase-8 elevated in pulmonary tuberculosis [PDF]

, 2014
Tuberculosis (TB) remains a global health pandemic and greater understanding of underlying pathogenesis is required to develop novel therapeutic and diagnostic approaches.
Sandhu, G, Christopher H. Woelk, Carlton A. W. Evans, Gurjinder Sandhu (161147), Borislav D. Dimitrov (687966), Gurjinder Sandhu, Woelk Christopher H., Liku B. Tezera, Akul Singhania, Thomas, Richard, Agranoff Dan, Sandhu Gurjinder, Liku B. Tezera (405129), Paul T. Elkington, Christopher H. Woelk (195217), Tezera, LB, Friedland Jon S., Jon S Friedland, Sathyamoorthy, Tarangini, Dimitrov, Borislav D., Sathyamoorthy, T, Singhania, A, Elkington, Paul T., Evans Carlton A. W., Agranoff, Dan, Evans, CAW, Richard Thomas, Elkington Paul T., Dimitrov, BD, Borislav D Dimitrov, Friedland, Jon S., Carlton A. W. Evans (687967), Christopher H Woelk, Dan Agranoff, Paul T Elkington, Paul T. Elkington (364501), Tarangini Sathyamoorthy (687964), Agranoff, D, Jon S. Friedland (161158), Tezera, Liku B., Sathyamoorthy Tarangini, Woelk, Christopher H., Borislav D. Dimitrov, Richard Thomas (687965), Akul Singhania (502117), Evans, Carlton A.W., Singhania, Akul, Jon S. Friedland, Tarangini Sathyamoorthy, Liku B Tezera, Sandhu, Gurjinder, Friedland, JS, Carlton A W Evans, Tezera Liku B., Thomas, R, Elkington, PT, Thomas Richard, Woelk, CH, Singhania Akul, Dan Agranoff (377996), Dimitrov Borislav D.   +60 more
core   +1 more source