Results 11 to 20 of about 140,703 (263)

The role of matrix metalloproteinase 9 in immune-mediated skin diseases [PDF]

Frontiers in Immunology
MMP-9, dependent on zinc, is a key endopeptidase involved in tissue homeostasis, inflammation, and immune-related pathological processes through its role in extracellular matrix degradation and remodeling.
Ke Xu, Min Li, Min Li, Fengming Hu, Fengming Hu, Jian Gong, Jian Gong, Fangrong Liu, Qiao Liu, Weiwei Wu, Weiwei Wu   +10 more
doaj   +2 more sources

The role of MMP-2 and MMP-9 in the metastasis and development of hypopharyngeal carcinoma

Brazilian Journal of Otorhinolaryngology, 2021
Introduction: The role of matrix metalloproteinase-2 and 9 in the metastasis and development of hypopharyngeal carcinoma has not been clarified. Objectives: To observe the relationship between matrix metalloproteinase-2, matrix metalloproteinase-9 and ...
Zhe Song, Junfu Wang, Qinghong Su, Meng Luan, Xuemei Chen, Xiaoqun Xu   +5 more
doaj   +1 more source

Regulation of Matrix Metalloproteinase-2 and Matrix Metalloproteinase-9 in Abdominal Aortic Aneurysm

Cardiology Discovery, 2023
Abdominal aortic aneurysm (AAA) is a degenerative disease characterized by destruction and progressive expansion of the abdominal aortic wall. An AAA is typically defined as an enlargement of the abdominal aorta with diameter ≥3 cm or ≥50% greater than ...
Shuo Wang, Dan Liu, Xiaolin Zhang, Xiaoxiang Tian   +3 more
doaj   +1 more source

Immunohistochemical expression of matrix metalloproteinase -9 in invasive meningioma

SVU - International Journal of Medical Sciences, 2021
Background: Meningioma is a common intracranial tumor arising from the meningothelial (arachnoid) cells. Meningiomas are divided into 15 histological subtypes and three grades, including benign (grade I), atypical (grade II) and anaplastic (grade III ...
Samar U. Hasan*, Rasha M. Abdelkareem, Ahmed A. S. A. ELhakeem, Ali R. Hamdan, Eman M. S. Muhammad   +4 more
doaj   +1 more source

The relationship between metastasis and mmp-9 in sheep with pulmonary adenocarcinomas [PDF]

Kafkas Universitesi Veteriner Fakültesi Dergisi, 2022
Th is study aimed to evaluate the role of Matrix Metalloproteinase-9 in the metastasis of ovine pulmonary adenocarcinoma cases by immunohistochemical methods.
Emin KARAKURT, Enver BEYTUT, Serpil DAĞ, Hilmi NUHOĞLU, Ayfer YILDIZ, Emre KURTBAŞ   +5 more
doaj   +1 more source

Gelatinases A and B activities in the serum of patients with various coronary artery disease stages [PDF]

Vojnosanitetski Pregled, 2010
Background/Aim. The main characteristic of matrix metalloproteinases (MMPs) is the degradation of extracellular matrix. Synthesis of MMPs has been reported in coronary atherosclerotic lesions in patients with coronary disease (CD) suggesting a pathogenic
Radenković Sandra, Brajović Milan, Konjević Gordana, Gopčević Kristina   +3 more
doaj   +1 more source

Substrate Hydrolysis by Matrix Metalloproteinase-9* [PDF]

Journal of Biological Chemistry, 2001
The catalytic clefts of all matrix metalloproteinases (MMPs) have a similar architecture, raising questions about the redundancy in substrate recognition across the protein family. In the present study, an unbiased phage display strategy was applied to define the substrate recognition profile of MMP-9.
S J, Kridel, E, Chen, L P, Kotra, E W, Howard, S, Mobashery, J W, Smith   +5 more
openaire   +2 more sources

Biomarkers of Skin Graft Healing in Venous Leg Ulcers

Acta Dermato-Venereologica, 2022
There is a need for biomarkers that predict the success of transplantation of venous leg ulcers (with autologous split-thickness skin grafts). The primary objective of this exploratory study was to investigate the association between split-thickness skin
Klaus Kirketerp-Møller, Petra Doerfler, Nicole Schoefmann, Barbara Wolf-Winiski, Omid Niazi, Vibeke Pless, Tonny Karlsmark, Magnus Ågren   +7 more
doaj   +1 more source

Matrix metalloproteinase-9 expression in pterygium [PDF]

Arquivos Brasileiros de Oftalmologia, 2006
To assess matrix metalloproteinase (MMP)-9 expression in pterygium lesion.A prospective randomized clinical trial was done to evaluate the expression of matrix metalloproteinase in normal and in primary or recurrent pterygia in Tenon's capsule by immunohistochemical analysis and a computerized image analysis system.
Schellini, Silvana Artioli, Hoyama, Erika, Oliveira, Deilson Elgui de, Bacchi, Carlos Eduardo, Padovani, Carlos Roberto   +4 more
openaire   +6 more sources

Pathophysiological Role of Chymase-Activated Matrix Metalloproteinase-9

Biomedicines, 2022
Chymase present in mast cells can directly form matrix metalloproteinase (MMP)-9 from proMMP-9. Chymase-activated MMP-9 has been reportedly closely related to the pathogenesis of various diseases, and inflammation-related diseases in particular ...
Shinji Takai, Denan Jin
doaj   +1 more source