Results 161 to 170 of about 125,678 (300)

Analysis of expression of mRNA Matrix Metalloproteinase (MMP)-8 gene and Tissue Inhibitors of Metalloproteinase (MMP)-l in Intraperitoneal Adhesion after Usage of Hyaluronate acid- Carboxymethylcellulose (HA-CMC) or Virgin Coconut oil (vco) Jimmy PrnclcwcDr, Aryono Djuncd Pusponegoro2,Ibrehim Lebcdrr, Aniilsoutlslemr, Mochrmmrd Hrtte4' [PDF]

-Analysis of expression of mRNA Matrix\ud Metalloproteinase (MMP)-8 gene and Tissue Inhibitors\ud of Metalloproteinase (MMP)-l in Intraperitoneal\ud Adhesion after Usage of Hyaluronate acid-\ud Carboxymethylcellulose (HA-CMC) or Virgin Coconut\ud oil ...
(Baru) Asadul, Islam, Prof. dr
core  

Mineralized Cryogel/Hydrogel Constructs to Recapitulate Early Breast Cancer Bone Metastasis In Vitro

Advanced Science, EarlyView.
A new biphasic in vitro cryogel/hydrogel model of early breast cancer bone metastasis provides precise control over microenvironmental cues and microscopic access to the spatiotemporal cancer cell distribution. Deposited bone‐like mineral is observed to strongly impede the effects of biomolecular signals, as evidenced by both colonization profiles and ...
Jana Sievers‐Liebschner, Petra B. Welzel, Maximilian Fusenig, Linda Sturm, Dagmar Pette, Wolfgang Wagermaier, Claudia Fischbach, Peter Fratzl, Carsten Werner   +8 more
wiley   +1 more source

TRAP5 Inhibition Targeting Scar‐Associated Macrophages Ameliorates Acute Kidney Injury to Chronic Kidney Disease Transition

Advanced Science, EarlyView.
This study delineates macrophage heterogeneity along the acute kidney injury to chronic kidney disease transition. Single‐cell RNA sequencing reveals a TRAP5+ scar‐associated macrophage subset driven by Spp1–Cd44 signaling and mitochondrial metabolic reprogramming.
Chenxi Wang, Yaodong Gu, Wen Du, Lin Xie, Jinwei Quan, Yu Zhao, Ye Cheng, Zhaonan Wei, Yuanyuan Sha, Yi Wang, Dechao Xu, Xiang Gao, Min Chen, Xiangchen Gu   +13 more
wiley   +1 more source

Matrix Metalloproteinase Inhibitor [PDF]

, 2020
openaire   +1 more source

Gut Microbiota‐Non‐Coding RNA Axis in Immune Modulation and Disease: From Mechanisms to Clinical Translation

Advanced Science, EarlyView.
ABSTRACT Immune homeostasis is indispensable for preserving organismal integrity, orchestrated through complex molecular networks encompassing immune cell dynamics, microbial cues, and epigenetic regulation. Among these, the gut microbiota‐non‐coding RNA (ncRNA) axis has recently garnered substantial attention as a multifaceted modulator of host ...
Bonan Chen, Guoming Chen, Xieyuan Leng, Qianfan Li, Wenhao Wu, Wenqiu Wu, Zixuan Liu, Zilan Zhong, Xiaohong Zheng, Wei Kang, Fazheng Ren, Yigan Zhang, Juan Chen   +12 more
wiley   +1 more source

In Vitro Effect of Using Endo-Activator on Pushout Bond Strength of Radicular Dentin to Prefabricated Fiber Post in Using Natural Matrix Metalloproteinase Inhibitors. [PDF]

Clin Exp Dent Res
Elyassi Gorji N, Alaghemand H, Mokhtarpour F, Mahmodnia E.   +3 more
europepmc   +1 more source

Multimodal AI‐Driven Identification of Dehydrocostus Lactone as a Potent Renal Fibrosis Attenuator Targeting IQGAP1

Advanced Science, EarlyView.
Renal fibrosis, a hallmark of CKD, lacks effective treatments. Herein, we developed a multimodal AI model (TCM‐SPred) to identify anti‐fibrotic agents and found that dehydrocostus lactone (DCL) targets IQGAP1 to inhibit Wnt signaling, blocking the interaction between IQGAP1 and CCT3, demonstrating potent anti‐fibrotic activity in vitro and in vivo ...
Weijiang Lin, Wenzhuo Xu, Kang Liu, Ping Wang, Zhenzhen Zhu, Wenyu Lu, Zhe Zheng, Xiaoqian Peng, Xunkai Yin, Shulan Mei, An Pan, Jian Liu, Lihong Hu   +12 more
wiley   +1 more source

Effect of Different Matrix Metalloproteinase Inhibitors on the Shear Bond Strength of Composite Attached to Dentin: An In Vitro Study on Permanent Teeth. [PDF]

Cureus
Chaudhuri P, Wang CK, Pal S, Singh AK, Chatterjee A, Ramalingam K, Banerjee A.   +6 more
europepmc   +1 more source

Macrophage Extracellular Traps in Immunity and Cancer

Advanced Science, EarlyView.
As a macrophage‐mediated innate defense mechanism, the dysregulated release of METs drives chronic inflammation and influences tumor progression. Furthermore, METs exhibit a functional duality within the tumor microenvironment, capable of both promoting and suppressing tumor development.
Junyao Li, Eugenie Nepovimova, Adam Grundel, Lukas Peter, Qinghua Wu, Kamil Kuca   +5 more
wiley   +1 more source

Proteolytic dysfunction in bovine digital dermatitis caused by Treponema spp. and the therapeutic use of non-antimicrobial matrix metalloproteinase inhibitors. [PDF]

Commun Biol
Lahiri P, Young D, Penner R, Lesack K, Dias AP, Hannawayya R, De Buck J, Orsel K, Hollenberg MD, Johnson F, Golub L, Scaduto J, Dufour A, Cobo ER.   +13 more
europepmc   +1 more source