Results 91 to 100 of about 3,510,435 (284)

Conformal matrix models as an alternative to conventional multi-matrix models [PDF]

open access: yesNuclear Physics B, 1993
35 pages, preprint FIAN/TD-9/92 & ITEP-M-4 ...
Kharchev, S.   +4 more
openaire   +2 more sources

Modeling hepatic fibrosis in TP53 knockout iPSC‐derived human liver organoids

open access: yesMolecular Oncology, EarlyView.
This study developed iPSC‐derived human liver organoids with TP53 gene knockout to model human liver fibrosis. These organoids showed elevated myofibroblast activation, early disease markers, and advanced fibrotic hallmarks. The use of profibrotic differentiation medium further amplified the fibrotic signature seen in the organoids.
Mustafa Karabicici   +8 more
wiley   +1 more source

Dinámica poblacional de la palma Euterpe oleracea (Arecaceae) en bosques inundables del Chocó, Pacífico colombiano

open access: yesRevista de Biología Tropical, 2010
La palma Euterpe oleracea es una especie dominante y promisoria en el plano inundable del río Atrato, región del Chocó, Colombia. Nosotros evaluamos la dinámica poblacional de esta especie a través de las tasas de crecimiento, la mortalidad y los ...
Diego A Arango   +2 more
doaj  

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

open access: yesMolecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert   +13 more
wiley   +1 more source

Patient‐specific pharmacogenomics demonstrates xCT as predictive therapeutic target in colon cancer with possible implications in tumor connectivity

open access: yesMolecular Oncology, EarlyView.
This study integrates transcriptomic profiling of matched tumor and healthy tissues from 32 colorectal cancer patients with functional validation in patient‐derived organoids, revealing dysregulated metabolic programs driven by overexpressed xCT (SLC7A11) and SLC3A2, identifying an oncogenic cystine/glutamate transporter signature linked to ...
Marco Strecker   +16 more
wiley   +1 more source

Mortality rate estimation for eelgrass Zostera marina (Potamogetonaceae) using projections from Leslie matrices

open access: yesRevista de Biología Tropical, 2008
The main goal of this study is to provide estimations of mean mortality rate of vegetative shoots of the seagrass Zostera marina in a meadow near Ensenada Baja California, using a technique that minimizes destructive sampling.
Olga Flores Uzeta   +2 more
doaj  

Vital rates and population trajectory of a declining eastern wild turkey population in southeastern Oklahoma

open access: yesWildlife Society Bulletin
The eastern wild turkey (Meleagris gallopavo silvestris; hereafter, wild turkey) is a culturally and economically important game species in North America, yet populations have shown apparent declines across their distribution. Oklahoma, USA, has not been
Nicolle Butler   +9 more
doaj   +1 more source

On matrix models and their q-deformations

open access: yesJournal of High Energy Physics, 2020
Motivated by the BPS/CFT correspondence, we explore the similarities be- tween the classical β-deformed Hermitean matrix model and the q-deformed matrix models associated to 3d N $$ \mathcal{N} $$ = 2 supersymmetric gauge theories on D 2 × q S 1 and S b ...
Luca Cassia   +2 more
doaj   +1 more source

Matrix models for circular ensembles [PDF]

open access: yes, 2004
We describe an ensemble of (sparse) random matrices whose eigenvalues follow the Gibbs distribution for n particles of the Coulomb gas on the unit circle at inverse temperature beta.
Killip, R., Nenciu, I.
core   +1 more source

Predictors of response and rational combinations for the novel MCL‐1 inhibitor MIK665 in acute myeloid leukemia

open access: yesMolecular Oncology, EarlyView.
This study characterizes the responses of primary acute myeloid leukemia (AML) patient samples to the MCL‐1 inhibitor MIK665. The results revealed that monocytic differentiation is associated with MIK665 sensitivity. Conversely, elevated ABCB1 expression is a potential biomarker of resistance to the treatment, which can be overcome by the combination ...
Joseph Saad   +17 more
wiley   +1 more source

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