Results 81 to 90 of about 3,508,679 (285)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Matrix models on the fuzzy sphere [PDF]
Field theory on a fuzzy noncommutative sphere can be considered as a particular matrix approximation of field theory on the standard commutative sphere. We investigate from this point of view the scalar $\phi^4$ theory.
AP Balachandran +10 more
core +2 more sources
Cell surface interactome analysis identifies TSPAN4 as a negative regulator of PD‐L1 in melanoma
Using cell surface proximity biotinylation, we identified tetraspanin TSPAN4 within the PD‐L1 interactome of melanoma cells. TSPAN4 negatively regulates PD‐L1 expression and lateral mobility by limiting its interaction with CMTM6 and promoting PD‐L1 degradation.
Guus A. Franken +7 more
wiley +1 more source
Background independent matrix models [PDF]
A class of background independent matrix models is made for which the structure of both local gauge symmetries and classical solutions is clarified. These matrix models do not involve a space-time metric and provide the matrix analogs of topological Chern-Simons and BF theories.
openaire +2 more sources
Flows for rectangular matrix models
Several new results on the multicritical behavior of rectangular matrix models are presented. We calculate the free energy in the saddle point approximation, and show that at the triple-scaling point, the result is the same as that derived from the ...
Lafrance, Rene, Myers, Robert C.
core +1 more source
LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix +13 more
wiley +1 more source
A generating function for knot diagrams is constructed. We consider a matrix model with d(N×N) matrices and show that in the limits N→∞ and d→0 the model describes the knot diagrams. The same limit in matrix string theory is also discussed. We speculate that a prototypical M(atrix) without matrix theory exists in void.
Aref'eva, I. Ya., Volovich, I. V.
openaire +2 more sources
Conformal matrix models as an alternative to conventional multi-matrix models [PDF]
35 pages, preprint FIAN/TD-9/92 & ITEP-M-4 ...
Kharchev, S. +4 more
openaire +2 more sources
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
La palma Euterpe oleracea es una especie dominante y promisoria en el plano inundable del río Atrato, región del Chocó, Colombia. Nosotros evaluamos la dinámica poblacional de esta especie a través de las tasas de crecimiento, la mortalidad y los ...
Diego A Arango +2 more
doaj

