Results 101 to 110 of about 156,207 (304)

The Stiff Side of Cancer: How Matrix Mechanics Rewrites Non-Coding RNA Expression Programs

open access: yesNon-Coding RNA
Extracellular matrix (ECM) stiffening is a defining biophysical feature of solid tumors that reshape gene regulation through mechanotransduction. Increased collagen crosslinking and stromal remodeling enhance integrin engagement, focal-adhesion signaling
Alma D. Campos-Parra   +6 more
doaj   +1 more source

Comparison of several closure approximations for evaluating the thermoelastic properties of an injection molded short-fiber composite [PDF]

open access: yes, 2007
The accurate prediction of both the elastic properties and the thermal expansion coefficients is very important for the precise simulation of such processes as injection molding of short-fiber polymer-matrix composites.
DRAY, Delphine   +2 more
core   +1 more source

Soft Mechanical‐Electrical Logic Using Liquid Metal‐Filled 3D‐Printed Architectures

open access: yesAdvanced Engineering Materials, EarlyView.
We present 3D‐printed soft mechanical–electrical logic elements that use liquid metal–filled silicone tubes actuated by thermoplastic polyurethane/polylactic acid (TPU/PLA) architectures to produce Boolean operations. Complementary normally open and normally closed unit cells perform repeatable binary transitions and can be combined into more complex ...
Christoph Lehmann   +2 more
wiley   +1 more source

Macrophage polarization in ischemia–reperfusion injury: from molecular mechanisms to therapeutic strategies

open access: yesFrontiers in Immunology
Ischemia–reperfusion injury (IRI) induces secondary tissue damage following the restoration of blood flow. Currently, there is a lack of specific therapeutic interventions for IRI.
Xiaoyang Han   +10 more
doaj   +1 more source

Application of finite element methods to the post-buckling behaviour of thin plates containing imperfections [PDF]

open access: yes, 1978
A finite element program, applicable to the pre- and post-buckling behaviour of plates with imperfections, is developed. Suitable incremental stiffness matrices are generated for a plate element with four nodes and twenty degrees of freedom ...
Allahyari, H.
core  

41 - Computation of Element Stiffness Matrix

open access: yes, 2016
A simple example of a frame model is presented to shows how to examine the computational details of the element stiffness matrix, using the educational function. The items of computation include the element stiffness matrix and force vector, respectively
Lee, Jae Young
core   +1 more source

Matrix stiffness regulates osteoclast fate through integrin-dependent mechanotransduction

open access: yes, 2023
Osteoclasts ubiquitously participate in bone homeostasis, and their aberration leads to bone diseases, such as osteoporosis. Current clinical strategies by biochemical signaling molecules often perturb innate bone metabolism owing to the uncontrolled ...
Changsheng Liu   +3 more
core   +1 more source

Direct Metal Deposition of Graphene–Ti28Nb35.4Zr Matrix Composites With Enhanced Mechanical, Corrosion, and Biocompatibility Properties for Bone Implants

open access: yesAdvanced Engineering Materials, EarlyView.
Graphene nanoplatelet (0.1 wt.%) reinforcement significantly enhances the performance of β Ti‐28Nb‐35.4Zr alloy. Grain refinement, reduced water contact angle, and improved surface characteristics promote osteoblast adhesion and complete surface coverage after 7 days.
Khurram Munir   +5 more
wiley   +1 more source

A patient-specific computer tomography-based finite element methodology to calculate the six dimensional stiffness matrix of human vertebral bodies

open access: yes, 2012
In most finite element (FE) studies of vertebral bodies, axial compression is the loading mode of choice to investigate structural properties, but this might not adequately reflect the various loads to which the spine is subjected during daily activities
Chevalier, Yan, Zysset, Philippe K.
core   +1 more source

In Situ Micromechanical Study of Bimodal γ′–γ″ Precipitate Assemblies in Ni–Cr–Al–Nb Superalloy

open access: yesAdvanced Engineering Materials, EarlyView.
A Ni–Cr–Al–Nb superalloy with a bimodal γ′–γ″ precipitate distribution is developed. Composite precipitate assemblies form through heterogeneous nucleation, effectively impeding dislocation motion. Micropillar compression reveals high strength at room and elevated temperatures, governed by precipitate shearing, with coupled faulting mechanisms ...
Ujjval Bansal   +4 more
wiley   +1 more source

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