Results 101 to 110 of about 4,695,396 (296)
, 2020 Although the matricellular protein periostin is prominently upregulated in skin and gingival healing, it plays contrasting roles in myofibroblast differentiation and matrix synthesis respectively.
Nikoloudaki, Georgia +4 more
core +1 more source
CEACAM1 participation in breast cancer progression
Molecular Oncology, EarlyView.In invasive breast cancer (BC), CEACAM1 shifts from an apical to a uniform membranous/cytoplasmic pattern, or is lost, as tumors dedifferentiate, inversely tracking the Ki‐67 proliferative index. In MCF‐7 cells, only CEACAM1‐4L suppresses proliferation, repressing cell cycle and growth factor genes.
Mykola Lyndin +3 more
wiley +1 more source
Research Progress on Synthesis and Application of Graphene Reinforced Metal Matrix Composites
Cailiao gongcheng, 2018 Graphene, a two-dimensional carbon material made up of a single atomic layer structure, shows unique physical and chemical properties.Graphene reinforced metal matrix composites have attracted more and more attention due to excellent properties.In this ...
WANG Jian-qiao +4 more
doaj +1 more source
Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer
Molecular Oncology, EarlyView.Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas +16 more
wiley +1 more source
PANoptosis in the pathogenesis of myelodysplastic syndromes
Molecular Oncology, EarlyView.PANoptosis, a combination of three types of programmed cell death, is mediated by a large protein complex called a PANoptosome. In healthy bone marrow hematopoietic cells, PANoptosis is restricted by inhibitory signaling. In MDS, bone marrow cells become sensitive to the PANoptotic stimuli due to the aberrant inactivation of inhibitory signaling or ...
Rohit Thalla +4 more
wiley +1 more source
Mechanisms and therapeutic opportunities of the ribotoxic stress response in cancer
Molecular Oncology, EarlyView.Cancer cells' high translational demand creates opportunities to therapeutically target ribosome function. Ribosome stalling and collisions activate ZAKα and the ribotoxic stress response (RSR), which can trigger rapid, p53‐independent apoptosis in cancer.
Anastassiya Kim +7 more
wiley +1 more source
Algorithms for analysis and synthesis of systems with synchronization errors
, 2012 This thesis addresses currently open problems in the stability analysis and control of discrete linear systems with clock synchronisation errors. Such errors can lead to insta- bility of an overall system even in the case when it is composed of linear ...
Przedwojski, Marek
core
A New Method of Multiple Plane Curve Numerical Synthesis
Jixie chuandong, 2016 Aiming at the problem of numerical synthesis on conjugate curve processed by pre-grinding bob,a new method of arbitrarily complex multiple plane curves numerical synthesis to a curve is given.
Zhang Zhizi, Tang Jinyuan
doaj
Molecular Oncology, EarlyView.This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic +10 more
wiley +1 more source
In Situ Synthesis of a Wear Resistant Layer on the Surface of Low Carbon Steel produced by Laser Melt Injection Technology [PDF]
, 2013 Titanium and his compounds are one of the most frequently used reinforcing particles in iron – ceramic composite materials. These materials will possess special characteristics because they are quenchable, their hardness can be increased by heat ...
Búza, Gábor +2 more
core +1 more source