Results 81 to 90 of about 4,695,396 (296)
Membrane composition and thermodynamic identity as boundaries of life for synthetic cell research
FEBS Letters, EarlyView.What makes a cell a cell? The boundary of a living cell is not just a wall. Read as a Markov blanket, the membrane separates internal from external states, generating identity and non‐equilibrium order. Can this identity be rebuilt from scratch in a synthetic cell?
Caterina Presutti, Bert Poolman
wiley +1 more source
Gradient System Modelling of Matrix Converters with Input and Output Filters [PDF]
, 2003 Due to its complexity, the dynamics of matrix converters are usually neglected in controller design. However, increasing demands on reduced harmonic generation and higher bandwidths makes it necessary to study large-signal dynamics. A unified methodology
Scherpen, Jacquelien M.A., +5 more
core +1 more source
The role of miR‐335‐5p in the redifferentiation of BRAF p.V600E thyroid cancers
Molecular Oncology, EarlyView.The BRAF p.V600E mutation promotes thyroid cancer dedifferentiation and radioiodine resistance. Using a network approach, we identified miR‐335‐5p as a key regulator of BRAF‐mutated thyroid tumors. Restoring miR‐335‐5p increased thyroid‐specific gene expression and iodine uptake in cells and organoids.
Valeria Pecce +11 more
wiley +1 more source
Synthesis of Nanoparticles in a Silicate Matrix [PDF]
, 2021 Nanoparticle synthesis is the driving force behind research and development in nanotechnology. The development of more tailored nanoparticles for different uses is increasing the need for more efficient and cleaner synthetic methods.
Estrada-Mendoza, Tatiana Alexandra
core +1 more source
Compressive behaviour of metal matrix syntactic foams [PDF]
, 2012 The compressive behaviour of three different metal matrix syntactic foams (MMSFs) were investigated. The results showed that the engineering factors as the size of the used hollow spheres, the aspect ratio (height / diameter ratio) of the specimens and ...
Ginsztler, János, Orbulov, Imre Norbert
core +2 more sources
Sociobiology, 2014 Use of chitin synthesis inhibitors has revolutionized the potential impact of termite baiting systems. Several chitin synthesis inhibitors have been used or tested against subterranean termites.
Bal Krishna Gautam, Gregg Henderson
doaj +3 more sources
Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment
Molecular Oncology, EarlyView.This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley +1 more source
Matrix metalloproteinases at key junctions in the pathomechanism of stroke [PDF]
, 2011 Matrix metalloproteinases play a crucial role in the remodelling of the extracellular matrix through direct degradation of its structural proteins and control of extracellular signaling.
Kolev, Kraszimir +5 more
core +1 more source
Mechano-regulation of proline metabolism and cancer progression by kindlin-2
Molecular & Cellular Oncology, 2019 Alterations of cell mechano-environment and metabolism are common features of malignant neoplasm. We recently showed that increased stiffness of extracellular matrix is intrinsically linked to up-regulation of proline synthesis through a mechano ...
Ling Guo, Chuanyue Wu
doaj +1 more source
Molecular Oncology, EarlyView.Cytarabine is a key therapy for acute myeloid leukaemia (AML), but its efficacy is limited by the dNTPase SAMHD1, which hydrolyses its active metabolite. Screening nucleotide biosynthesis inhibitors revealed that IMPDH inhibitors selectively sensitise SAMHD1‐proficient AML cells to cytarabine.
Miriam Yagüe‐Capilla +9 more
wiley +1 more source