Results 151 to 160 of about 1,879,090 (387)

Disordered but rhythmic—the role of intrinsic protein disorder in eukaryotic circadian timing

FEBS Letters, EarlyView.
Unstructured domains known as intrinsically disordered regions (IDRs) are present in nearly every part of the eukaryotic core circadian oscillator. IDRs enable many diverse inter‐ and intramolecular interactions that support clock function. IDR conformations are highly tunable by post‐translational modifications and environmental conditions, which ...
Emery T. Usher, Jacqueline F. Pelham
wiley   +1 more source

Bio-banding in academy football: player’s perceptions of a maturity matched tournament

Annals of Human Biology, 2019
Background: Individual differences in biological maturation impact player selection and development in youth football. Aim: To evaluate players perceptions of competing in a football tournament where they were matched by maturity rather than ...
Ben Bradley, David Johnson, Megan Hill, Darragh McGee, Adam Kana-ah, Callum Sharpin, Peter Sharp, Adam Kelly, Sean P. Cumming, Robert M. Malina   +9 more
doaj   +1 more source

Clinical Assisted Reproduction: Cumulus Cell Contribution to Cytoplasmic Maturation and Oocyte Developmental Competence In Vitro [PDF]

, 2001
Hassan Aly Hassan
openalex   +1 more source

Maturation

Arthroplasty Today, 2023
openaire   +3 more sources

Cardiomyocyte maturation: advances in knowledge and implications for regenerative medicine

Nature Reviews Cardiology, 2020
Elaheh Karbassi, Aidan M. Fenix, S. Marchianò, Naoto Muraoka, Kenta Nakamura, Xiulan Yang, C. Murry   +6 more
semanticscholar   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

The role of histone modifications in transcription regulation upon DNA damage

FEBS Letters, EarlyView.
This review discusses the critical role of histone modifications in regulating gene expression during the DNA damage response (DDR). By modulating chromatin structure and recruiting repair factors, these post‐translational modifications fine‐tune transcriptional programmes to maintain genomic stability.
Angelina Job Kolady, Siyao Wang
wiley   +1 more source

Cubbing in proapolipoprotein maturation [PDF]

, 2011
Godfrey S. Getz, Catherine A. Reardon
openalex   +1 more source

Integration of circadian and hypoxia signaling via non‐canonical heterodimerization

FEBS Letters, EarlyView.
CLOCK, BMAL1, and HIFs are basic helix‐loop‐helix and Per‐Arnt‐Sim domain (bHLH‐PAS) proteins, which function as transcription factors. bHLH‐PAS proteins are designated in two classes. Many class I proteins are regulated by environmental signals via their PAS domains, but such signals have not been identified for all.
Sicong Wang, Katja A. Lamia
wiley   +1 more source

Substrate specificity of Burkholderia pseudomallei multidrug transporters is influenced by the hydrophilic patch in the substrate‐binding pocket

FEBS Letters, EarlyView.
Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley   +1 more source