Results 231 to 240 of about 1,879,090 (387)

Subcellular IIIG9 dynamics in cell-cell adhesion during ependymal cell specification and maturation from radial glia progenitors

, 2019
Victor Baeza, Maria-Jose Oviedo, Manuel Cifuentes, Francisco Nualart, Katterine Salazar   +4 more
openalex   +1 more source

PYCR1 inhibition in bone marrow stromal cells enhances bortezomib sensitivity in multiple myeloma cells by altering their metabolism

Molecular Oncology, EarlyView.
This study investigated how PYCR1 inhibition in bone marrow stromal cells (BMSCs) indirectly affects multiple myeloma (MM) cell metabolism and viability. Culturing MM cells in conditioned medium from PYCR1‐silenced BMSCs impaired oxidative phosphorylation and increased sensitivity to bortezomib.
Inge Oudaert, Lauren van den Broecke, Osman Aksoy, Judith Lind, Sonia Vallet, Arne Van der Vreken, Gamze Ates, Ann Massie, Ken Maes, Kim De Veirman, Elke De Bruyne, Karin Vanderkerken, Klaus Podar, Eline Menu   +13 more
wiley   +1 more source

Formation and Maturation of Phase-Separated Liquid Droplets by RNA-Binding Proteins.

Molecules and Cells, 2015
Yuan Lin, David S. W. Protter, M. Rosen, R. Parker   +3 more
semanticscholar   +1 more source

In vitro properties of patient serum predict clinical outcome after high dose rate brachytherapy of hepatocellular carcinoma

Molecular Oncology, EarlyView.
Following high dose rate brachytherapy (HDR‐BT) for hepatocellular carcinoma (HCC), patients were classified as responders and nonresponders. Post‐therapy serum induced increased BrdU incorporation and Cyclin E expression of Huh7 and HepG2 cells in nonresponders, but decreased levels in responders.
Lukas Salvermoser, Jan Niklas Schäfer, Shraga Nahum Goldberg, Philipp Maximilian Kazmierczak, Moritz Nikolaus Gröper, Philipp Franz Linden, Elif Öcal, Tanja Burkard, Stefanie Corradini, Najib Ben Khaled, Moritz Wildgruber, Max Seidensticker, Jens Ricke, Matthias Stechele, Marianna Alunni‐Fabbroni   +14 more
wiley   +1 more source

Developmental competence of alpaca oocytes matured <i>in vivo</i> with seminal plasma and following additional <i>in vitro</i> maturation. [PDF]

Anim Reprod
Silva Huanca NM, Cornelio Díaz VH, Auqui Rojas LA, Huaman Apaza AI, Huanca López W.   +4 more
europepmc   +1 more source

The DEAD-box RNA Helicase RH50 Is a 23S-4.5S rRNA Maturation Factor that Functionally Overlaps with the Plastid Signaling Factor GUN1 [PDF]

, 2017
Francesca Paieri, Luca Tadini, Nikolay Manavski, Tatjana Kleine, Roberto Ferrari, Piero Morandini, Paolo Pesaresi, Jörg Meurer, Dario Leister   +8 more
openalex   +1 more source

A synthetic benzoxazine dimer derivative targets c‐Myc to inhibit colorectal cancer progression

Molecular Oncology, EarlyView.
Benzoxazine dimer derivatives bind to the bHLH‐LZ region of c‐Myc, disrupting c‐Myc/MAX complexes, which are evaluated from SAR analysis. This increases ubiquitination and reduces cellular c‐Myc. Impairing DNA repair mechanisms is shown through proteomic analysis.
Nicharat Sriratanasak, Bodee Nutho, Worawat Wattanathana, Narumon Phaonakrop, Bunnatut Panasawatwong, Katharina Erlenbach‐Wuensch, Sittiruk Roytrakul, Regine Schneider‐Stock, Pithi Chanvorachote   +8 more
wiley   +1 more source

A practical tip for estimating skeletal maturation in children aged < 3 years using humeral ossification on chest radiographs: A retrospective study. [PDF]

Eur J Pediatr
Tsuru T, Inoue S, Edo H, Suzuki S, Imai K, Nozaki T, Shinmoto H.   +6 more
europepmc   +1 more source

Rejoining Veins for Forced Maturation of Small-Caliber Arteriovenous Fistula [PDF]

Miju Bae, Chung Won Lee, Sung Woon Chung, Up Huh, Jongwon Kim, Hyuncheol Jeong, Na Hyeon Lee   +6 more
openalex   +1 more source

Adaptaquin is selectively toxic to glioma stem cells through disruption of iron and cholesterol metabolism

Molecular Oncology, EarlyView.
Adaptaquin selectively kills glioma stem cells while sparing differentiated brain cells. Transcriptomic and proteomic analyses show Adaptaquin disrupts iron and cholesterol homeostasis, with iron chelation amplifying cytotoxicity via cholesterol depletion, mitochondrial dysfunction, and elevated reactive oxygen species.
Adrien M. Vaquié, Davod R. Shah, Eliane E. S. Brechbühl, Michael McNicholas, Zhaoyang Xu, John H. Stockley, Laura Morcom, Diana Gold Diaz, Gemma C. Girdler, Rachel V. Seear, Gabriel Balmus, Rajiv R. Ratan, Harry Bulstrode, James A. Nathan, Manav Pathania, Kevin M. Brindle, David H. Rowitch   +16 more
wiley   +1 more source