Results 61 to 70 of about 1,879,090 (387)

Stereotactic Body Radiation Therapy for Pediatric, Adolescent, and Young Adult Patients With Osteosarcoma: Local Control Outcomes With Dosimetric Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Osteosarcoma is a radioresistant tumor that may benefit from stereotactic body radiation therapy (SBRT) for locoregional control in metastatic/recurrent disease. We report institutional practice patterns, outcomes, toxicity, and failures in osteosarcoma patients treated with SBRT.
Jenna Kocsis, Shauna R. Campbell, Jonathan Jang, Eashwar Somasundaram, Chandana A. Reddy, Jacob G. Scott, Lilyana Angelov, Peter M. Anderson, Matteo Trucco, Zachary Burke, Lukas Nystrom, Nathan Mesko, Anthony Magnelli, Erin S. Murphy   +13 more
wiley   +1 more source

P53 Activation Promotes Maturational Characteristics of Pluripotent Stem Cell‐Derived Cardiomyocytes in 3‐Dimensional Suspension Culture Via FOXO‐FOXM1 Regulation

Journal of the American Heart Association: Cardiovascular and Cerebrovascular Disease
Background Current protocols generate highly pure human induced pluripotent stem cell–derived cardiomyocytes (hiPSC‐CMs) in vitro that recapitulate characteristics of mature in vivo cardiomyocytes.
Nivedhitha Velayutham, Jessica C. Garbern, Hannah L. T. Elwell, Zhu Zhuo, Laura Rüland, Farid Elcure Alvarez, Sara Frontini, Yago Rodriguez Carreras, Marie Eichholtz, Elisabeth Ricci‐Blair, Jeanna Y. Shaw, Aldric H. Bouffard, Morgan Sokol, Estela Mancheño Juncosa, Seth Rhoades, Daphne van den Berg, Alexander Kreymerman, Junya Aoyama, Jens Höfflin, Herb Ryan, Shannan Ho Sui, Richard T. Lee   +21 more
doaj   +1 more source

Maturation of the gut microbiome and risk of asthma in childhood

Nature Communications, 2018
The composition of the human gut microbiome matures within the first years of life. It has been hypothesized that microbial compositions in this period can cause immune dysregulations and potentially cause asthma.
J. Stokholm, M. Blaser, J. Thorsen, M. Rasmussen, Johannes Waage, R. Vinding, A. Schoos, Asja Kunøe, N. R. Fink, B. Chawes, K. Bønnelykke, A. Brejnrod, Martin Steen Mortensen, W. Al-Soud, S. Sørensen, H. Bisgaard   +15 more
semanticscholar   +1 more source

Changes in Body Composition in Children and Young People Undergoing Treatment for Acute Lymphoblastic Leukemia: A Systematic Review and Meta‐Analysis

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Ongoing evidence indicates increased risk of sarcopenic obesity among children and young people (CYP) with acute lymphoblastic leukemia (ALL), often beginning early in treatment, persisting into survivorship. This review evaluates current literature on body composition in CYP with ALL during and after treatment.
Lina A. Zahed, Raquel Revuelta Iniesta, Mary Fewtrell, Julie Lanigan, Breeana Gardiner, Graeme O'Connor   +5 more
wiley   +1 more source

Towards Sulphite-Free Winemaking: A New Horizon of Vinification and Maturation

Foods
The complex dynamics between oxygen exposure, sulphur dioxide (SO2) utilization, and wine quality are of the utmost importance in wine sector, and this study aims to explore their fine balance in winemaking.
Nicola Mercanti, Monica Macaluso, Ylenia Pieracci, Guido Flamini, Giulio Scappaticci, Andrea Marianelli, Angela Zinnai   +6 more
doaj   +1 more source

Engineering the Vasculature of Stem-Cell-Derived Liver Organoids

Biomolecules, 2021
The vasculature of stem-cell-derived liver organoids can be engineered using methods that recapitulate embryonic liver development. Hepatic organoids with a vascular network offer great application prospects for drug screening, disease modeling, and ...
Xv Zhang, Liling Tang, Qian Yi
doaj   +1 more source

Differential rates of perinatal maturation of human primary and nonprimary auditory cortex [PDF]

, 2018
Primary and nonprimary cerebral cortex mature along different timescales; however, the differences between the rates of maturation of primary and nonprimary cortex are unclear.
Brownell, Abraham, Eaton-Rosen, Zach, Inder, Terri E, Kapur, Kush, Liebenthal, Einat, Monson, Brian B, Neil, Jeffrey J, Rogers, Cynthia E, Smyser, Christopher D, Warfield, Simon K   +9 more
core   +2 more sources

Parent‐to‐Child Information Disclosure in Pediatric Oncology

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background Despite professional consensus regarding the importance of open communication with pediatric cancer patients about their disease, actual practice patterns of disclosure are understudied. Extant literature suggests a significant proportion of children are not told about their diagnosis/prognosis, which is purported to negatively ...
Rachel A. Kentor, Flora Hoodin, Michelle Byrd, Kristin A. Kullgren, Leah LaLonde, Lauren Benkoske, Patrick Smith, Dawn Carson, Karen MacDonald, Susumu Inoue, Brenda Kitchen, Kate Gowans, Gregory A. Yanik   +12 more
wiley   +1 more source

Regeneration of roots and shoots as a propagation strategy in Eugenia candolleana DC. (Myrtaceae) seeds

Journal of Seed Science
: Seeds of the genus Eugenia have high regenerative capacity, producing roots and shoots from seeds with reduced cotyledon matter. In addition, seeds of this genus regenerate new roots and shoots when the first roots and shoots are eliminated, and this ...
Camila Rivero Alonso, Maiara Iadwizak Ribeiro, Marina Crestana Guardia, Claudio José Barbedo   +3 more
doaj   +1 more source

A Systematic Review of Evidence on the Clinical Effectiveness of Surveillance Imaging in Children With Medulloblastoma and Ependymoma

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Surveillance imaging aims to detect tumour relapse before symptoms develop, but it's unclear whether earlier detection of relapse leads to better outcomes in children and young people (CYP) with medulloblastoma and ependymoma. This systematic review aims to identify relevant literature to determine the efficacy of surveillance magnetic ...
Lucy Shepherd, Melissa Taylor, Helen Fulbright, Bob Phillips   +3 more
wiley   +1 more source