Results 101 to 110 of about 542,377 (310)
Mapping the evolution of mitochondrial complex I through structural variation
Respiratory complex I (CI) is crucial for bioenergetic metabolism in many prokaryotes and eukaryotes. It is composed of a conserved set of core subunits and additional accessory subunits that vary depending on the organism. Here, we categorize CI subunits from available structures to map the evolution of CI across eukaryotes. Respiratory complex I (CI)
Dong‐Woo Shin +2 more
wiley +1 more source
A Multidimensional Maturity Model for the Metaverse: Stages, Dimensions and Architectural Alignment
The Metaverse has become a central concept in the evolution of digital transformation, but its current development is marked by conceptual ambiguity, technological fragmentation and the limited presence of structured frameworks for the systematic ...
Joan-Marc Garcés Sabaté +1 more
doaj +1 more source
Glucose inhibits cardiac muscle maturation through nucleotide biosynthesis. [PDF]
The heart switches its energy substrate from glucose to fatty acids at birth, and maternal hyperglycemia is associated with congenital heart disease. However, little is known about how blood glucose impacts heart formation.
Braas, Daniel +21 more
core +2 more sources
Organoids in pediatric cancer research
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley +1 more source
Validation of macroscopic maturity stages of the Patagonian red octopus Enteroctopus megalocyathus [PDF]
Testes and ovaries of Enteroctopus megalocyathus collected along the Patagonian Atlantic coast were analysed histologically to validate the macroscopic maturity scales adopted for this species.
Ortiz, Nicolás
core +2 more sources
Reciprocal control of viral infection and phosphoinositide dynamics
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley +1 more source
Inaccuracies in routinely collected Atlantic herring (Clupea harengus) maturity data and correction using a gonadosomatic index model [PDF]
Peer reviewedPublisher ...
Ganias, Konstantinos +2 more
core +1 more source
Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes +3 more
wiley +1 more source
El tomate (Lycopersicon esculentum), la hortaliza más sembrada en Colombia, es considerada una de las más importantes por su volumen de producción y demanda.
KATHERIN CASTRO +3 more
doaj

