Results 51 to 60 of about 492,566 (255)

Numerical modeling of the equatorial electrojet UT-variation on the basis of the model GSM TIP [PDF]

open access: yesAdvances in Radio Science, 2007
In the presented work the results of numerical modeling of the UT-variation of the equatorial electrojet, executed on the basis of the model GSM TIP are presented, taking into account the dynamo electric fields generated by thermospheric winds in a ...
M. V. Klimenko   +2 more
doaj  

Curtis homomorphisms and the integral Bernstein center for GL_n

open access: yes, 2020
We describe two conjectures, one strictly stronger than the other, that give descriptions of the integral Bernstein center for GL_n(F) (that is, the center of the category of smooth W(k)[GL_n(F)]-modules, for F a p-adic field and k an algebraically ...
Helm, David
core   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Expanding the boundaries: investigating the integration of contextual information across a spectrum of inter-trial variability

open access: yesFrontiers in Psychology
It is well-documented that feature integration across perception and action creates a retrievable episodic representation, known as a stimulus-response episode or an event file.
Ruyi Qiu, Yanzhi Mo
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Uplifts of maximal supergravities and transitions to non-geometric vacua

open access: yes, 2019
We describe a new procedure to obtain consistent backgrounds that uplift vacua and deformations of various maximal gauged supergravities by taking a known solution and performing singular limits along the moduli space of the corresponding 4-dimensional ...
Dall'Agata, Gianguido   +2 more
core   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

GABAA receptor agonists modulate intracellular Ca2+ levels in activated human CD4+ T cells

open access: yesFrontiers in Immunology
GABA binding to GABAA receptors induces transient elevation in intracellular Ca2+ concentrations in activated human CD4+ T cells. Here we examined the Ca2+ response evoked by the GABAA receptor agonists THIP, muscimol, isoguvacine, and TACA and further ...
Sergiy V. Korol   +4 more
doaj   +1 more source

The Structure of Promises in Quantum Speedups [PDF]

open access: yes, 2014
It has long been known that in the usual black-box model, one cannot get super-polynomial quantum speedups without some promise on the inputs. In this paper, we examine certain types of symmetric promises, and show that they also cannot give rise to ...
Ben-David, Shalev
core  

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

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