Results 91 to 100 of about 14,117,029 (318)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Two open problems for absolutely convergent Dirichlet series [PDF]

open access: yesМатематичні Студії, 2012
For the absolutely convergent in a half-plane Dirichlet series we establish upper estimates without exceptional sets.
O. B. Skaskiv, O. Yu. Zadorozhna
doaj  

Sharp inequalities for the variation of the discrete maximal function [PDF]

open access: yes, 2015
In this paper we establish new optimal bounds for the derivative of some discrete maximal functions, both in the centered and uncentered versions. In particular, we solve a question originally posed by Bober, Carneiro, Hughes and Pierce.
Jos'e Madrid
semanticscholar   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

Fractional Maximal Functions in Metric Measure Spaces

open access: yesAnalysis and Geometry in Metric Spaces, 2013
We study the mapping properties of fractional maximal operators in Sobolev and Campanato spaces in metric measure spaces. We show that, under certain restrictions on the underlying metric measure space, fractional maximal operators improve the Sobolev ...
Heikkinen Toni   +3 more
doaj   +1 more source

The (Glg)ABCs of cyanobacteria: modelling of glycogen synthesis and functional divergence of glycogen synthases in Synechocystis sp. PCC 6803

open access: yesFEBS Letters, EarlyView.
We reconstituted Synechocystis glycogen synthesis in vitro from purified enzymes and showed that two GlgA isoenzymes produce glycogen with different architectures: GlgA1 yields denser, highly branched glycogen, whereas GlgA2 synthesizes longer, less‐branched chains.
Kenric Lee   +3 more
wiley   +1 more source

Structural biology of ferritin nanocages

open access: yesFEBS Letters, EarlyView.
Ferritin is a conserved iron‐storage protein that sequesters iron as a ferric mineral core within a nanocage, protecting cells from oxidative damage and maintaining iron homeostasis. This review discusses ferritin biology, structure, and function, and highlights recent cryo‐EM studies revealing mechanisms of ferritinophagy, cellular iron uptake, and ...
Eloise Mastrangelo, Flavio Di Pisa
wiley   +1 more source

Maximal Functions Associated to Filtrations

open access: yesJournal of Functional Analysis, 2001
Let \((X,\mu)\) and \((Y,\nu)\) be arbitrary measure spaces. To any sequence of measurable subsets \(\{Y_n \}\) of \(Y\) and any bounded linear operator \(T: L^p(Y) \to L^q(X)\) one can associate the maximal operator \(T^*f(x)=\sup_n |T(f \cdot \chi_{Y_n})(x)|\), where \(\chi_{Y_n}\) designates the characteristic function of \(Y_n\). It is proved that \
Christ, Michael, Kiselev, Alexander
openaire   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

open access: yesFEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Bent Functions of Maximal Degree

open access: yesIEEE Transactions on Information Theory, 2012
In this paper, a technique for constructing p-ary bent functions from plateaued functions is presented. This generalizes earlier techniques of constructing bent from near-bent functions. The Fourier spectrum of quadratic monomials is analyzed, and examples of quadratic functions with highest possible absolute values in their Fourier spectrum are given.
Çeşmelioğlu, Ayça, Meidl, Wilfried
openaire   +3 more sources

Home - About - Disclaimer - Privacy