Results 111 to 120 of about 12,719,951 (362)

Nonself-Adjoint Second-Order Difference Operators in Limit-Circle Cases

open access: yesAbstract and Applied Analysis, 2012
We consider the maximal dissipative second-order difference (or discrete Sturm-Liouville) operators acting in the Hilbert space ℓ2đ‘€(â„€) (â„€:={0,±1,±2,
}), that is, the extensions of a minimal symmetric operator with defect index (2,2) (in the Weyl ...
Bilender P. Allahverdiev
doaj   +1 more source

An upstream open reading frame regulates expression of the mitochondrial protein Slm35 and mitophagy flux

open access: yesFEBS Letters, EarlyView.
This study reveals how the mitochondrial protein Slm35 is regulated in Saccharomyces cerevisiae. The authors identify stress‐responsive DNA elements and two upstream open reading frames (uORFs) in the 5â€Č untranslated region of SLM35. One uORF restricts translation, and its mutation increases Slm35 protein levels and mitophagy.
HernĂĄn Romo‐Casanueva   +5 more
wiley   +1 more source

HĂƒÆ’Ă‚Â¶lder Quasicontinuity in Variable Exponent Sobolev Spaces

open access: yesJournal of Inequalities and Applications, 2007
We show that a function in the variable exponent Sobolev spaces coincides with a HĂƒÆ’Ă‚Â¶lder continuous Sobolev function outside a small exceptional set.
Katja Tuhkanen   +2 more
doaj   +1 more source

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
PrzemysƂaw Dutka   +11 more
wiley   +1 more source

Vector-Valued Inequalities in the Morrey Type Spaces

open access: yesInternational Journal of Mathematics and Mathematical Sciences, 2014
We will obtain the strong type and weak type estimates for vector-valued analogues of classical Hardy-Littlewood maximal function, weighted maximal function, and singular integral operators in the weighted Morrey spaces Lp,Îș(w) when 1 ...
Hua Wang
doaj   +1 more source

A matrix weighted bilinear Carleson Lemma and Maximal Function

open access: yes, 2018
We prove a bilinear Carleson embedding theorem with matrix weight and scalar measure. In the scalar case, this becomes exactly the well known weighted bilinear Carleson embedding theorem. Although only allowing scalar Carleson measures, it is to date the
Petermichl, Stefanie   +2 more
core  

Sequence determinants of RNA G‐quadruplex unfolding by Arg‐rich regions

open access: yesFEBS Letters, EarlyView.
We show that Arg‐rich peptides selectively unfold RNA G‐quadruplexes, but not RNA stem‐loops or DNA/RNA duplexes. This length‐dependent activity is inhibited by acidic residues and is conserved among SR and SR‐related proteins (SRSF1, SRSF3, SRSF9, U1‐70K, and U2AF1).
Naiduwadura Ivon Upekala De Silva   +10 more
wiley   +1 more source

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

open access: yesFEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li   +2 more
wiley   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

open access: yesFEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan   +5 more
wiley   +1 more source

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