Results 131 to 140 of about 1,683,952 (323)

Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib

Molecular Oncology, EarlyView.
WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute, Júlia Huguet‐Pradell, Jordi Abril‐Fornaguera, Albert Gris‐Oliver, Alex Rialdi, Elisa Fernández‐Martínez, Carla Montironi, Vanessa Del Pozo, Peter Houghton, Laura Zanatto, Agavni Mesropian, Ieva Keraite, Swan Thung, Carolina Armengol, Pau Sancho‐Bru, Ernesto Guccione, Roser Pinyol, Josep M. Llovet   +17 more
wiley   +1 more source

Commutators for the maximal and sharp functions with weighted Lipschitz functions on weighted Morrey spaces

Demonstratio Mathematica
We study the boundedness of commutators of the Hardy-Littlewood maximal function and the sharp maximal function on weighted Morrey spaces when the symbols of the commutators belong to weighted Lipschitz spaces (weighted Morrey-Campanato spaces). Some new
Zhang Pu, Fan Di
doaj   +1 more source

About Borel type relation for some positive functional series

Математичні Студії
Let $f$ be an entire transcendental function, $(\lambda_n)$ be a non-decreasing to $+\infty$ sequence, $M_f(r)=\max\{|f(z)|\colon |z|=r\}$, and $\Gamma_f(r)/r=(\ln M_f(r))'_+$ be a right derivative, $r>0$.
A.Yu. Bodnarchuk, O.B. Skaskiv, O.M. Trusevych   +2 more
doaj   +1 more source

Maximal functions on classical Lorentz spaces and Hardy’s inequality with weights for nonincreasing functions [PDF]

, 1990
Miguel Á. Ariño, Benjamin Muckenhoupt
openalex   +1 more source

Exploiting metabolic adaptations to overcome dabrafenib treatment resistance in melanoma cells

Molecular Oncology, EarlyView.
We show that dabrafenib‐resistant melanoma cells undergo mitochondrial remodeling, leading to elevated respiration and ROS production balanced by stronger antioxidant defenses. This altered redox state promotes survival despite mitochondrial damage but renders resistant cells highly vulnerable to ROS‐inducing compounds such as PEITC, highlighting redox
Silvia Eller, Susanne Ebner, Carmen Haselrieder, Julia K. Günther, Astrid Drasche, Sophie Strich, Chiara Volani, Andrea Medici, Aleksandar Nikolajevic, Alex Deltedesco, Johannes E. Sigmund, Michael J. Blumer, Martin Hermann, Johanna Vanacker, Gerald Brandacher, Eduard Stefan, Omar Torres‐Quesada, Jakob Troppmair   +17 more
wiley   +1 more source

Hölder Quasicontinuity in Variable Exponent Sobolev Spaces

Journal of Inequalities and Applications, 2007
We show that a function in the variable exponent Sobolev spaces coincides with a Hölder continuous Sobolev function outside a small exceptional set.
Kinnunen Juha, Tuhkanen Katja, Harjulehto Petteri   +2 more
doaj  

Discrete Relationships between Spatiotemporal Gait Characteristics and Domain-Specific Neuropsychological Performance in Midlife

Sensors
Midlife risk factors such as type 2 diabetes mellitus (T2DM) confer a significantly increased risk of cognitive impairment in later life with executive function, memory, and attention domains often affected first.
Laura Morrison, Adam H. Dyer, Helena Dolphin, Isabelle Killane, Nollaig M. Bourke, Matthew Widdowson, Conor P. Woods, James Gibney, Richard B. Reilly, Sean P. Kennelly   +9 more
doaj   +1 more source

The Ergodic Maximal Function with Cancellation

The Annals of Probability, 1976
A variant of the ergodic maximal function is studied. This maximal function reduces to the usual one for $f \geqq 0$, but the cancellation between the positive and negative parts of $f$ causes interesting behavior. In particular the maximal function can be in $L^1$ even when the function is not in $L \log^+ L$.
openaire   +3 more sources

Monitoring of circulating tumor DNA allows early detection of disease relapse in patients with operable breast cancer

Molecular Oncology, EarlyView.
Monitoring circulating tumor DNA (ctDNA) in patients with operable breast cancer can reveal disease relapse earlier than radiology in a subset of patients. The failure to detect ctDNA in some patients with recurrent disease suggests that ctDNA could serve as a supplement to other monitoring approaches.
Kristin Løge Aanestad, Marie Austdal, Oddmund Nordgård, Gunnar Mellgren, Satu Oltedal, Marie L. Austbø, Ylva H. Vignes, Thomas Helland, Kristin Jonsdottir, Tone H. Lende, Emilius A. M. Janssen, Bjørnar Gilje, Kjersti Tjensvoll, PBCB study group, Gunnar Mellgren, Tone Hoel Lende, Anette Heie, Kristin Viste, Anita Røyneberg Alvheim, Emiel AM Janssen, Kristin Jonsdottir, Ann Cathrine Kroksveen, Thomas Helland, Einar Gudlaugsson, Oddmund Nordgård, Satu Oltedal, Kristin Løge Aanestad, Jan Terje Kvaløy, Kirsten Lode, Kari Britt Hagen, Marie Austdal, Ylva H. Vignes, Siri Tungland Sola, Nina Egeland Amundsen, Finn Magnus Eliassen, Emeritus Ernst A Lien   +35 more
wiley   +1 more source

Maximal Operators, Littlewood–Paley Functions and Variation Operators Associated with Nonsymmetric Ornstein–Uhlenbeck Operators [PDF]

, 2023
Víctor Almeida, Jorge J. Betancor, Pablo Quijano, Lourdes Rodríguez–Mesa   +3 more
openalex   +1 more source