Results 61 to 70 of about 4,946,680 (242)

Effect of DFPP on Ferroptosis in Peripheral Blood CD14+ Monocytes of Hyperlipidemic Patients Involving the ACSL4/LPCAT3/ALOX5 Pathway

open access: yesTherapeutic Apheresis and Dialysis, EarlyView.
ABSTRACT Introduction Hyperlipidemia is a major risk factor for atherosclerotic cardiovascular disease (ASCVD). Although statins are the cornerstone of lipid‐lowering therapy, their use may be limited in some patients by adverse effects. This study evaluated the possible impact of non‐drug treatment using double‐filtration plasmapheresis (DFPP) on CD14+
Yun Cheng   +3 more
wiley   +1 more source

Enteropathogenic E. coli shows delayed attachment and host response in human jejunum organoid‐derived monolayers compared to HeLa cells

open access: yesFEBS Letters, EarlyView.
Enteropathogenic E. coli (EPEC) infects the human intestinal epithelium, resulting in severe illness and diarrhoea. In this study, we compared the infection of cancer‐derived cell lines with human organoid‐derived models of the small intestine. We observed a delayed in attachment, inflammation and cell death on primary cells, indicating that host ...
Mastura Neyazi   +5 more
wiley   +1 more source

On some properties of the maximal term of series in systems of functions

open access: yesМатематичні Студії
For an entire transcendental function $f$ and a sequence $(\lambda_n)$ of positive numbers increa\-sing to $+\infty$ a series $A(z)=\sum_{n=1}^{\infty}a_nf(\lambda_n z)$ in the system $\{f(\lambda_nz)\}$ is said to be regularly convergent in ${\mathbb C}
M. M. Sheremeta, Yu. M. Gal'
doaj   +1 more source

Organoids in pediatric cancer research

open access: yesFEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

On maximal immediate extensions of valued division algebras [PDF]

open access: yes, 2003
We show an extension theorem for strictly contracting bilinear mappings into a spherically complete valued vector space and we apply this result to prove that every maximal valued division algebra having the same characteristic as its residue division ...
Schörner, Erwin
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Changes of maximal flow regime in Arctic [PDF]

open access: yesСтроительство уникальных зданий и сооружений, 2014
For the Russian Arctic territory, expected changes of multi-annual maximal flow statistics is estimated for the period of 2010-39. Results are obtained for the climate scenarios SRES:A2, SRES:A1B and SRES:B1 for four projections from Global Circulation ...
Elena Valentinovna Shevnina
doaj  

Using the Maximal Entropy Modeling Approach to Analyze the Evolution of Sedentary Agricultural Societies in Northeast China

open access: yesEntropy, 2020
The emergence of agriculture and the evolution of sedentary societies are among the most important processes in human history. However, although archeologists and social scientists have long been studying these processes, our understanding of them is ...
Ido Wachtel   +2 more
doaj   +1 more source

Salmonella lipopolysaccharide‐containing supported lipid bilayers as platforms to study bacteriophage interactions

open access: yesFEBS Letters, EarlyView.
We present robust protocols for the preparation of supported lipid bilayers (SLBs) incorporating either Salmonella smooth LPS or outer membrane vesicles (OMVs). We use a combination of quartz crystal microbalance with dissipation (QCM‐D) and fluorescence microscopy to both characterize the SLBs of various compositions and to probe their interactions ...
Hudson P. Pace   +6 more
wiley   +1 more source

Reconstructing enzyme evolution by protein engineering

open access: yesFEBS Letters, EarlyView.
Natural enzyme evolution can be retraced by protein engineering methods such as directed evolution, rational design, and ancestral sequence reconstruction. These approaches reveal how enzymes emerged from ligand‐binding scaffolds, developed varying substrate preferences, formed oligomeric complexes, adapted to environmental changes, and evolved novel ...
Lukas Drexler   +2 more
wiley   +1 more source

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