Results 121 to 130 of about 1,228,420 (310)

Airborne radar evidence for tributary flow switching in Institute Ice Stream, West Antarctica: implications for ice sheet configuration and dynamics [PDF]

, 2015
Despite the importance of ice streaming to the evaluation of West Antarctic Ice Sheet (WAIS) stability we know little about mid- to long-term dynamic changes within the Institute Ice Stream (IIS) catchment.
Martin J. Siegert, Hugh F. J. Corr, Corr, Hugh, Bingham, RG, Woodward, John, Ross, Neil, Ross, N, Dunning, SA, Corr, Hugh F.J., Winter, K, Siegert, MJ, Robert G. Bingham, Winter, Kate, Dunning, Stuart, John Woodward, Neil Ross, Siegert, Martin, Corr, HFJ, Kate Winter, Dunning, Stuart A., Siegert, Martin J., Stuart A. Dunning, Bingham, Robert G., Woodward, J   +23 more
core   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Maximum bipartite matching problem via maximum flow in flow networks

, 2014
Ovaj rad bavi se problemom pronalaska maksimalnog sparivanja bipartitnog grafa pomoću maksimalnog toka. U radu je dan opći prikaz bitnijih definicija vezanih uz grafove te mreže toka kao i način prikazivanja grafova na računalima.
Spajić, Zvonimir
core  

An Alzheimer's Disease Mechanism Based on Early Pathology, Anatomy, Vascular-Induced Flow, and Migration of Maximum Flow Stress Energy Location with Increasing Vascular Disease. [PDF]

J Alzheimers Dis, 2022
Trumbore CN, Raghunandan A.
europepmc   +1 more source

The maximum flow in a network

, 2008
The work describes how to find the maximum flow in a network. It has two parts - theoretic and programmatic. The theoretic part desribes founded maximum flow algorithms.
Tichá, Michaela
core   +1 more source

A maximum flow-based network approach for identification of stable noncoding biomarkers associated with the multigenic neurological condition, autism. [PDF]

BioData Min, 2021
Varma M, Paskov KM, Chrisman BS, Sun MW, Jung JY, Stockham NT, Washington PY, Wall DP.   +7 more
europepmc   +1 more source

Heterozygous loss‐of‐function alleles associate the conserved 3′‐5′ exoribonuclease EXOSC10 with hypersensitivity to the anticancer drug 5‐fluorouracil

Molecular Oncology, EarlyView.
EXOSC10, an essential nuclear RNA exosome‐associated 3′‐5′ exoribonuclease, is inhibited by the anticancer drug 5‐fluorouracil (5‐FU), and EXOSC10 depletion increases 5‐FU sensitivity. The colon‐cancer variant EXOSC10S402T, located in a proteolysis motif, is stable and nuclear but nonfunctional in vivo.
Radhika Sain, Yann Le Page, Frédéric Percevault, Emmanuelle Becker, Luc Negroni, Almudena Fernandez, Marta Cantero, Diego Muñoz‐Santos, Lluís Montoliu, Cyrille Garnier, Michael Primig   +10 more
wiley   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

Assessing the design maximum discharges values in the lower pool of hydroelectric power plants

Водное хозяйство России: проблемы, технологии, управление
One of the important tasks of engineering hydrology and river runoff regulation, the solution of which is not fully regulated by current regulatory and methodological documents, is the determination of the design maximum discharges in the lower pools of
Mikhail V. Bolgov
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source