A yeast model of 5‐oxoproline accumulation reveals a general toleration to 5‐oxoproline
FEBS Open Bio, EarlyView.Using a yeast model, we show that even high accumulation of 5‐oxoproline causes only mild cellular stress and does not trigger oxidative stress. Instead, cells adapt by activating efflux pumps and diverse protective pathways, suggesting that previously proposed harmful effects of 5‐oxoproline may arise from indirect metabolic imbalances rather than the
Pratiksha Dubey +4 more
wiley +1 more source
FEBS Open Bio, EarlyView.In normal (nontolerant) cells, CD14 is crucial for both LPS uptake and LPS signaling. In LPS‐tolerant cells, in which LPS‐induced TNF‐α and IFN‐β production is suppressed, there is a dramatic increase in surface CD14 expression. The overexpressed CD14 in LPS‐tolerant cells is responsible for the enhanced LPS uptake without inducing pro‐inflammatory ...
Saeka Nishihara +3 more
wiley +1 more source
NEW ALGORITHM FOR SOLUTION OF MAXIMUM FLOW PROBLEM
Наука и техника, 2013 A new algorithm for detection of a maximum flow in multi-terminal network. The algorithm is based on its matrices description and execution of ternary operations in respect of matrix elements pertaining to arc capacity.
A. D. Korznikov
doaj
FEBS Open Bio, EarlyView.Time‐restricted feeding (TRF) in mice increased liver fatty acid oxidation and decreased fatty acid biosynthesis. These alterations persisted when TRF was discontinued and the host was infected with Mycobacterium tuberculosis. Pre‐exposure to TRF did not alter tissue (lung and spleen) mycobacterial burden but significantly reduced CD3+ T cells in lungs
Ashish Gupta +7 more
wiley +1 more source
MAXIMUM PRINCIPLE FOR SUBSONIC FLOW WITH VARIABLE ENTROPY
Научный вестник МГТУ ГА, 2017 Maximum principle for subsonic flow is fair for stationary irrotational subsonic gas flows. According to this principle, if the value of the velocity is not constant everywhere, then its maximum is achieved on the boundary and only on the boundary of the
G. B. Sizykh
doaj
Relationship between visual prostate score (VPSS) and maximum flow rate (Qmax) in men with urinary tract symptoms. [PDF]
Int Braz J Urol, 2016 Memon MA, Ather MH.
europepmc +1 more source
Aquaporin‐3 and aquaporin‐5 impact the development of pancreatic ductal adenocarcinoma spheroids
FEBS Open Bio, EarlyView.Schematic representation of the role of aquaporin‐3 (AQP3) and aquaporin‐5 (AQP5) in pancreatic ductal adenocarcinoma (PDAC). Both proteins are upregulated in PDAC and are associated with tumor progression and metastatic potential. Silencing AQP3 or AQP5 in PDAC spheroids results in decreased diameter, area, and overall growth, underscoring their key ...
Catarina Pimpão +3 more
wiley +1 more source
Individualized volume-corrected maximum flow rate correlates with outcome from bladder outlet surgery in men with lower urinary tract symptoms. [PDF]
Int J Urol, 2016 Bray A, Harding C, Pickard R, Drinnan M.
europepmc +1 more source
Importin 7 mediates the nuclear import of HIV‐1 integrase via a specific interacting interface
FEBS Open Bio, EarlyView.HIV‐1 integrase enables viral DNA integration into the host genome. By binding to the core domain of the host protein Importin 7 via its C‐terminal domain, the integrase is transported across the nuclear membrane into the nucleus, where integration of the viral genome into host DNA takes place. This translocation is a critical step for subsequent viral
Juana Bana +5 more
wiley +1 more source
Maximum flow approach to prioritize potential drug targets of Mycobacterium tuberculosis H37Rv from protein-protein interaction network. [PDF]
Clin Transl Med, 2015 Melak T, Gakkhar S.
europepmc +1 more source