Results 131 to 140 of about 1,228,420 (310)

New distance-directed algorithms for maximum flow and parametric maximum flow problems

HD28 .M414 no. 1908-, 87,
Ahuja, Ravindra K., 1956-, Maximum flow and parametric maximum flow problems, New distance-directed algorithms for., Orlin, James B., 1953-.   +2 more
core  

Segmentation and Multimodal Characterization of Metal Particles in the Human Hippocampus Using Discrete Segmentation Algorithms and Correlation Spectral Analysis

Molecules
The accumulation of metallic micro- and nanoparticles in the human hippocampus is increasingly linked to neurotoxic processes and neurodegenerative disorders.
Ján Pánik, Mária Ždímalová, Daniel Kosnáč, Martin Kopáni, Silvia Dulanská, Nazarii Kretsul, Michal Trnka   +6 more
doaj   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

DNA methylation and expression of MAPRE3 affect overall survival of early‐stage non‐small cell lung cancer patients

Molecular Oncology, EarlyView.
Both cg12821679MAPRE3 methylation and MAPRE3 expression are significantly associated with overall survival (OS) of non‐small cell lung cancer. Meanwhile, MAPRE3 expression significantly modified the effect of smoking cessation on OS. Smoking cessation benefits OS merely for patients with high MAPRE3 expression.
Chao Chen, Jiancheng Cheng, Ruili Hou, Xiaoyuan Zheng, Li Su, Maria Moksnes Bjaanæs, Anna Karlsson, Maria Planck, Johan Staaf, Åslaug Helland, Manel Esteller, David C. Christiani, Feng Chen, Xiaofei Cao, Ruyang Zhang   +14 more
wiley   +1 more source

Numerical simulation of bubbles deformation, flow and coalescence in a microchannel under pseudo-nucleation conditions

, 2009
This paper was presented at the 2nd Micro and Nano Flows Conference (MNF2009), which was held at Brunel University, West London, UK. The conference was organised by Brunel University and supported by the Institution of Mechanical Engineers, IPEM, the ...
Zu, Y, 2nd Micro and Nano Flows Conference (MNF2009), Yan, Y   +2 more
core  

Liquid-Liquid Flow in a Capillary Microreactor: Hydrodynamic Flow Patterns and Extraction Performance

, 2012
The capillary micro reactor, with four stable operating flow patterns and a throughput range from grams per hour to kilograms per hour, presents an attractive alternative to chip-based and microstructured reactors for laboratory- and pilot-scale ...
Nijhuis, TA Xander = Alexander, Jovanovic, J Jovan, Hessel, V., Jovanovic, J., Kreutzer, M.T., Rebrov, Evgeny, Schouten, J.C., Rebrov, E.; id_orcid, Schouten, J C, Rebrov, E., Rebrov, E Evgeny, Kreutzer, MT, Hessel, V, Nijhuis, T.A.   +13 more
core   +1 more source

Circulating tumor cell viability during and after radiotherapy mirrors treatment response in cancer patients

Molecular Oncology, EarlyView.
Radiotherapy (RT) response depends on the DNA repair capacity of tumor and host cells. We show that circulating tumor cell (CTC) counts and apoptosis rates before and after RT predict treatment response and outcome, which can be accessed via easily accessible liquid biopsy approaches. Created in BioRender. Wikman, H.
Yvonne Goy, Jana Löptien, Cornelia Coith, Afroditi Nanou, Katharina Hintelmann, Pinnschmidt Hans, Cordula Petersen, Klaus Pantel, Sabine Riethdorf, Kerstin Borgmann, Harriet Wikman   +10 more
wiley   +1 more source

3-Dimensional Computational Analysis Of Fluid Flow Around Micro Flow Sensor At Different Positions And Pillar Arrangement Tony Tan Hin Jooqa297. [T161 2008 F Rb] [PDF]

, 2008
Analisis pengaliran bendalir mengelilingi pengesan mikro telah dipamerkan dalam penyelidikan ini. Dalam analisis tersebut, pengesan mikro dianggap dipasangkan dalam saluran berbentuk segi empat tepat.
Tan, Tony Hin Joo
core  

Determinación de Caudales en cuencas con poco información Hidrológica

Ciencia UNEMI, 2014
In most cases, in Ecuador there is a noticeable lack of hydrometric information, essential for the design of hydraulic projects. In order to overcome this disadvantage, have been developed some logical equations resulting from mass analysis to calculate ...
Sandoval Erazo, Washington Ramiro , Aguilera Ortiz, Eduardo Patricio   +1 more
doaj