Results 71 to 80 of about 2,646,945 (311)
FEBS Letters, EarlyView.Mycobacterial 3‐methylcrotonyl‐CoA carboxylase uses a mobile biotin‐carrying domain to shuttle a carboxyl group between two catalytic sites, enabling carboxylation of 3‐methylcrotonyl‐CoA during leucine breakdown. Cryo‐electron microscopy captures the carrier at both sites and reveals an inward loop movement that may prevent futile rebinding to the ...
Ajit Yadav +2 more
wiley +1 more source
Reducing the bias of the maximum likelihood estimator for the Poisson regression model [PDF]
We derive expressions for the first-order bias of the MLE for a Poisson regression model and show how these can be used to adjust the estimator and reduce bias without increasing MSE.
Hui Feng, David E Giles
core
The Shewanella oneidensis Fic enzyme SoFic targets the switch‐I region of EF‐Tu for AMPylation
FEBS Letters, EarlyView.Fic enzymes mediate diverse post‐translational modifications across all domains of life, including AMPylation. Prokaryotic EF‐Tu can be AMPylated and deAMPylated by the conserved Fic enzyme SoFic. Structural and biochemical approaches were used to characterize the effect of AMPylation on EF‐Tu, SoFic's enzymatic activities, and the enzyme‐target ...
Svenja Runge +6 more
wiley +1 more source
"Empirical Likelihood-Based Inference in Conditional Moment Restriction Models" [PDF]
This paper proposes an asymptotically efficient method for estimating models with conditional moment restrictions. Our estimator generalizes the maximum empirical likelihood estimator (MELE) of Qin and Lawless (1994).
Hyungtaik Ahn +2 more
core
Bayesian and Classical Estimation of Stress-Strength Reliability for Inverse Weibull Lifetime Models
Algorithms, 2017 In this paper, we consider the problem of estimating stress-strength reliability for inverse Weibull lifetime models having the same shape parameters but different scale parameters.
Qixuan Bi, Wenhao Gui
doaj +1 more source
FEBS Letters, EarlyView.Synechocystis strains deficient in succinate dehydrogenase (SDH) secrete more succinate than the WT under dark anaerobic conditions, supporting that SDH then primarily acts as SDH, not as a fumarate reductase. L‐aspartate oxidase (Laspo) from Synechocystis is functional under anaerobic conditions, reducing fumarate to succinate.
Kateryna Kukil +3 more
wiley +1 more source
A monte carlo analysis of the type II tobit maximum likelihood estimator when the true model is the type I tobit model [PDF]
Type I (censored regression) and Type II Tobit (sample selection) models are widely used in the various fields of economics. The Type I Tobit model is a special case of the Type II Tobit model.
Kazumitsu Nawata
core
Geodesic distances in the maximum likelihood estimator of intrinsic dimensionality
Nonlinear Analysis, 2011 While analyzing multidimensional data, we often have to reduce their dimensionality so that to preserve as much information on the analyzed data set as possible. To this end, it is reasonable to find out the intrinsic dimensionality of the data.
Rasa Karbauskaitė +2 more
doaj
Results in EngineeringThis study aims to address a central issue in continuous partially accelerated life testing for complete failure data by developing and comparing eight estimating methods for the two-parameter Odd Kappa-Exponential distribution, which features a flexible
Ali A. Al-Shomrani
doaj +1 more source
Large Deviations and Berry–Esseen Inequalities for Estimators in Nonlinear Nonhomogeneous Diffusions
Revstat Statistical Journal, 2007 Bounds on the large deviations probability of the maximum likelihood estimator and regular Bayes estimators, and Berry–Esseen type bound for the suitably normalized maximum likelihood estimator of a parameter appearing nonlinearly in the nonhomogeneous ...
Jaya P.N. Bishwal
doaj +1 more source