Results 91 to 100 of about 1,626,050 (291)

Crucial parameters for precise copy number variation detection in formalin‐fixed paraffin‐embedded solid cancer samples

Molecular Oncology, EarlyView.
This study shows that copy number variations (CNVs) can be reliably detected in formalin‐fixed paraffin‐embedded (FFPE) solid cancer samples using ultra‐low‐pass whole‐genome sequencing, provided that key (pre)‐analytical parameters are optimized.
Hanne Goris, Vasiliki Siozopoulou, Léon C van Kempen, Anne Sieben, Ella Roelant, Stig Hellemans, Elyne Backx, Laure Sorber, Koen De Winne, Senada Koljenović, Karen Zwaenepoel   +10 more
wiley   +1 more source

Correction of the Relative Coordinates by Range using the Maximum Likelihood Method

Известия высших учебных заведений России: Радиоэлектроника, 2016
The maximum likelihood estimating algorithm for complexion measurement of the relative coordinates and distance was created, the most efficient use of heterogeneous data sources is allowed.
V. K. Orlov, V. S. Ramadanov
doaj  

Phenotypic and genotypic characterization of single circulating tumor cells in the follow‐up of high‐grade serous ovarian cancer

Molecular Oncology, EarlyView.
Single circulating tumor cells (sCTCs) from high‐grade serous ovarian cancer patients were enriched, imaged, and genomically profiled using WGA and NGS at different time points during treatment. sCTCs revealed enrichment of alterations in Chromosomes 2, 7, and 12 as well as persistent or emerging oncogenic CNAs, supporting sCTC identity.
Carolin Salmon, Rui P. L. Neves, Nikolas H. Stoecklein, Sven‐Thorsten Liffers, Jens Siveke, Jan D. Kuhlmann, Pauline Wimberger, Paul Buderath, Rainer Kimmig, Sabine Kasimir‐Bauer   +9 more
wiley   +1 more source

Common Methods for Phylogenetic Tree Construction and Their Implementation in R

Bioengineering
A phylogenetic tree can reflect the evolutionary relationships between species or gene families, and they play a critical role in modern biological research.
Yue Zou, Zixuan Zhang, Yujie Zeng, Hanyue Hu, Youjin Hao, Sheng Huang, Bo Li   +6 more
doaj   +1 more source

A Distance-Based Maximum Likelihood Estimation Method for Sensor Localization in Wireless Sensor Networks

International Journal of Distributed Sensor Networks, 2016
Node localization is an important supporting technology in wireless sensor networks (WSNs). Traditional maximum likelihood estimation based localization methods (MLE) assume that measurement errors are independent of the distance between the anchor node ...
Jing Xu, Jingsha He, Yuqiang Zhang, Fei Xu, Fangbo Cai   +4 more
doaj   +1 more source

Negative Binomial mixed models estimated with the maximum likelihood method can be used for longitudinal RNAseq data. [PDF]

Brief Bioinform, 2021
Tsonaka R, Spitali P.
europepmc   +1 more source

The EM Algorithm [PDF]

The Expectation-Maximization (EM) algorithm is a broadly applicable approach to the iterative computation of maximum likelihood (ML) estimates, useful in a variety of incomplete-data problems.
Krishnan, Thriyambakam, McLachlan, Geoffrey J., Ng, See Ket   +2 more
core  

Combining antibody conjugates with cytotoxic and immune‐stimulating payloads maximizes anti‐cancer activity

Molecular Oncology, EarlyView.
Methods to improve antibody–drug conjugate (ADC) treatment durability in cancer therapy are needed. We utilized ADCs and immune‐stimulating antibody conjugates (ISACs), which are made from two non‐competitive antibodies, to enhance the entry of toxic payloads into cancer cells and deliver immunostimulatory agents into immune cells.
Tiexin Wang, Dong Jun Koo, Peter M. Tessier, Greg M. Thurber   +3 more
wiley   +1 more source

Dividing Social Networks into Two Communities Using the Maximum Likelihood Method: Application to ESG [PDF]

E3S Web of Conferences
This article explores the application of the Maximum Likelihood Estimation method (MLE) for community detection in environmental, social, and governance (ESG) networks.
Zakhidov Dilshodbek, Sagdillayeva Zulfiya, Moursy Ali R.A.   +2 more
doaj   +1 more source