Results 41 to 50 of about 4,636,575 (354)

A Maximum Principle for the Controlled Sweeping Process [PDF]

open access: yes, 2016
We consider the free endpoint Mayer problem for a controlled Moreau process, the control acting as a perturbation of the dynamics driven by the normal cone, and derive necessary optimality conditions of Pontryagin’s Maximum Principle type.
Chems Eddine Arroud, G. Colombo
semanticscholar   +1 more source

The IQ‐compete assay for measuring mitochondrial protein import efficiencies in living yeast cells

open access: yesFEBS Letters, EarlyView.
The efficiency of mitochondrial protein import depends on the properties of the newly synthesized precursor proteins. The Import and de‐Quenching Competition (IQ‐compete) assay is a novel method to monitor the import efficiency of different proteins by fluorescence in living yeast cells.
Yasmin Hoffman   +3 more
wiley   +1 more source

By dawn or dusk—how circadian timing rewrites bacterial infection outcomes

open access: yesFEBS Letters, EarlyView.
The circadian clock shapes immune function, yet its influence on infection outcomes is only beginning to be understood. This review highlights how circadian timing alters host responses to the bacterial pathogens Salmonella enterica, Listeria monocytogenes, and Streptococcus pneumoniae revealing that the effectiveness of immune defense depends not only
Devons Mo   +2 more
wiley   +1 more source

Interplay between circadian and other transcription factors—Implications for cycling transcriptome reprogramming

open access: yesFEBS Letters, EarlyView.
This perspective highlights emerging insights into how the circadian transcription factor CLOCK:BMAL1 regulates chromatin architecture, cooperates with other transcription factors, and coordinates enhancer dynamics. We propose an updated framework for how circadian transcription factors operate within dynamic and multifactorial chromatin landscapes ...
Xinyu Y. Nie, Jerome S. Menet
wiley   +1 more source

Second-order maximum principle controlled weakly singular Volterra integral equations [PDF]

open access: yesArchives of Control Sciences
This work studies a class of singular Volterra integral equations that are (controlled) and can be applied to memory-related problems. For optimum controls, we prove a second-order Pontryagin type maximal principle.
Jasarat J. Gasimov, Nazim I. Mahmudov
doaj   +1 more source

Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer

open access: yesFEBS Letters, EarlyView.
Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani   +4 more
wiley   +1 more source

Hopf maximum principle revisited

open access: yesElectronic Journal of Differential Equations, 2015
A weak version of Hopf maximum principle for elliptic equations in divergence form $$ \sum_{i,j=1}^N\partial_i(a_{ij}(x)\partial_ju)=0 $$ with Holder continuous coefficients $a_{ij}$ was shown in [3], in the two-dimensional case.
Jose C. Sabina de Lis
doaj  

Pontryagin Maximum Principle for Incommensurate Fractional-Orders Optimal Control Problems

open access: yesMathematics, 2023
We introduce a new optimal control problem where the controlled dynamical system depends on multi-order (incommensurate) fractional differential equations.
Faïçal Ndaïrou, Delfim F. M. Torres
doaj   +1 more source

Riemannian Formulation of Pontryagin’s Maximum Principle for the Optimal Control of Robotic Manipulators [PDF]

open access: gold, 2022
Juan Antonio Rojas-Quintero   +2 more
openalex   +1 more source

Emerging role of ARHGAP29 in melanoma cell phenotype switching

open access: yesMolecular Oncology, EarlyView.
This study gives first insights into the role of ARHGAP29 in malignant melanoma. ARHGAP29 was revealed to be connected to tumor cell plasticity, promoting a mesenchymal‐like, invasive phenotype and driving tumor progression. Further, it modulates cell spreading by influencing RhoA/ROCK signaling and affects SMAD2 activity. Rho GTPase‐activating protein
Beatrice Charlotte Tröster   +3 more
wiley   +1 more source

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