Results 41 to 50 of about 4,818,273 (341)

Maximum Principles at infinity

open access: yesJournal of Differential Geometry, 2008
We prove a general maximum principle at infinity for properly immersed minimal surfaces with boundary in R 3 . An important corollary of this maximum principle at infinity is the existence of a fixed sized regular neighborhood for any properly embedded minimal surface of bounded curvature.
Meeks, WH, Rosenberg, H
openaire   +3 more sources

Chemoresistome mapping in individual breast cancer patients unravels diversity in dynamic transcriptional adaptation

open access: yesMolecular Oncology, EarlyView.
This study used longitudinal transcriptomics and gene‐pattern classification to uncover patient‐specific mechanisms of chemotherapy resistance in breast cancer. Findings reveal preexisting drug‐tolerant states in primary tumors and diverse gene rewiring patterns across patients, converging on a few dysregulated functional modules. Despite receiving the
Maya Dadiani   +14 more
wiley   +1 more source

On Korenblum’s maximum principle [PDF]

open access: yesProceedings of the American Mathematical Society, 1997
Summary: If \(f\) and \(g\) are analytic functions in the unit disk and \(|\cdot|\) is the Bergman norm, conditions are studied under which there exists an absolute constant \(c\) such that \(|f(z)|\geq|g(z)|\) for \(c\leq|z|
openaire   +3 more sources

Molecular imaging predicts trastuzumab‐deruxtecan (T‐DXd) response in head and neck cancer xenograft models

open access: yesMolecular Oncology, EarlyView.
Trastuzumab‐deruxtecan, a HER2‐targeting antibody‐drug conjugate, shows promising antitumor activity in head and neck squamous cell carcinoma with low HER2 expression. In vitro and in vivo studies demonstrated dose‐dependent cell death and tumor growth reduction in low HER2‐expressing cell lines, which correlated with drug accumulation measured using a
Abdullah Bin Naveed   +8 more
wiley   +1 more source

Maximum principle for stable operators

open access: yesMathematische Nachrichten, 2023
AbstractWe prove a weak maximum principle for nonlocal symmetric stable operators including the fractional Laplacian. The main focus of this work is on minimal regularity assumptions of the functions under consideration.
Grube, Florian, Hensiek, Thorben
openaire   +3 more sources

Cytomegalovirus infection is common in prostate cancer and antiviral therapies inhibit progression in disease models

open access: yesMolecular Oncology, EarlyView.
Human cytomegalovirus infection is common in normal prostate epithelium, prostate tumor tissue, and prostate cancer cell lines. CMV promotes cell survival, proliferation, and androgen receptor signaling. Anti‐CMV pharmaceutical compounds in clinical use inhibited cell expansion in prostate cancer models in vitro and in vivo, motivating investigation ...
Johanna Classon   +13 more
wiley   +1 more source

Association of high‐dose radioactive iodine therapy with PPM1D‐mutated clonal hematopoiesis in older individuals

open access: yesMolecular Oncology, EarlyView.
In thyroid cancer patients, high‐dose (≥7.4 GBq) radioactive iodine therapy (RAIT) was associated with a higher prevalence of clonal hematopoiesis (variant allele frequency >2%) in individuals aged ≥50 years (OR = 2.44). In silico analyses showed that truncating PPM1D mutations conferred a selective advantage under these conditions.
Jaeryuk Kim   +11 more
wiley   +1 more source

Comprehensive profiling of lncRNAs and mRNAs enriched in small extracellular vesicles for early noninvasive detection of colorectal cancer: diagnostic panel assembly and extensive validation

open access: yesMolecular Oncology, EarlyView.
Small extracellular vesicles are a promising source of diagnostic molecules. We conducted a comprehensive study, including transcriptome profiling and RT‐qPCR validation on large cohorts of samples. Diagnostic panels enabling sensitive detection of colorectal cancer and precancerous lesions were established. Some molecules were differentially expressed
Petra Vychytilova‐Faltejskova   +26 more
wiley   +1 more source

The maximum principle for equations with composite coefficients

open access: yesElectronic Journal of Differential Equations, 2000
It is well-known that the maximum of the solution of a linear elliptic equation can be estimated in terms of the boundary data provided the coefficient of the gradient term is either integrable to an appropriate power or blows up like a small negative ...
Gary M. Lieberman
doaj  

Thermodynamic resource theories, non-commutativity and maximum entropy principles

open access: yesNew Journal of Physics, 2017
We discuss some features of thermodynamics in the presence of multiple conserved quantities. We prove a generalisation of Landauer principle illustrating tradeoffs between the erasure costs paid in different ‘currencies’.
Matteo Lostaglio   +2 more
doaj   +1 more source

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