Results 81 to 90 of about 1,263,980 (273)

CPX‐351 in High‐Risk Relapsed Pediatric Acute Leukemia: Real‐World Phase 1 Data Establishing the FDA‐Approved Dose

Pediatric Blood &Cancer, EarlyView.
ABSTRACT Background/Objectives Outcomes for pediatric relapsed/refractory (R/R) acute myeloid leukemia (AML) remain dismal. CPX‐351, a liposomal formulation of cytarabine and daunorubicin, may have less off‐target toxicities than traditional chemotherapies and has shown improved outcomes for adults with newly diagnosed therapy‐related AML.
Jonathan D. Bender, Lauren Pommert, Lori R. Backus, Andrea Bidwell, Courtney Blank, Erin H. Breese, Karen C. Burns, Adam Lane, Lynn H. Lee, Benjamin Mizukawa, Robin E. Norris, Maureen M. O'Brien, Daniel Peck, Christine Phillips, Thomas D. Ryan, Jennifer Young, Michael Absalon, John P. Perentesis   +17 more
wiley   +1 more source

Prospects for a certified mint supply chain in Morocco based on an assessment of consumers' willingness to pay [PDF]

, 2017
In Morocco, there is a weak control of the quality of fruits and vegetables on the domestic market. The present study assesses the prospects for a certified mint value chain (either complying with legal criteria of maximum residue level or using organic ...
Ait El Mekki, Abdelkader, Faysse, Nicolas, Jourdain, Damien, Raïs, Imane   +3 more
core  

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Detection of organochlorine compound in puyu, sepat and haruan fish caught from irrigation canals in paddy fields in Selangor and Perak, Malaysia [PDF]

, 2012
A case study was conducted to investigate the concentration of organochlorine pesticide residues in fish samples collected from irrigation canals in paddy fields in Tanjong Karang and Sekinchan, Selangor and Seberang Perak, Perak, Malaysia.
Abdul Rahman, Nur Azhani, Omar, Mohamed Ariff   +1 more
core  

Biowęgiel z pofermentacyjnej pozostałości kukurydzy hybrydowej - tani i wydajny sorbent metali ciężkich [PDF]

, 2019
Biochar produced from fermentation residue of maize hybrid was used in untreated form as a sorbent for the removal of Cd(II), Pb(II) and Zn(II) from aqueous solution.
Motyka, Oldřich, Seidlerová, Jana, Tokarčíková, Michaela, Šafaříková, Mirka   +3 more
core   +1 more source

Crosstalk between the ribosome quality control‐associated E3 ubiquitin ligases LTN1 and RNF10

FEBS Letters, EarlyView.
Loss of the E3 ligase LTN1, the ubiquitin‐like modifier UFM1, or the deubiquitinating enzyme UFSP2 disrupts endoplasmic reticulum–ribosome quality control (ER‐RQC), a pathway that removes stalled ribosomes and faulty proteins. This disruption may trigger a compensatory response to ER‐RQC defects, including increased expression of the E3 ligase RNF10 ...
Yuxi Huang, Satoshi Hashimoto, Sota Ito, Chisato Kikuguchi, Miho Hoshi, Kiyoshi Yamaguchi, Yoichi Furukawa, Toru Suzuki, Toshifumi Inada   +8 more
wiley   +1 more source

Guideline for handling pesticide residues in Czech organic production [PDF]

, 2013
This document was prepared in the project «Development of guidelines for the use of pesticide analysis in organic inspection in the Czech Republic (sampling, evaluation and interpretation)». At the beginning of this project, a workshop with stakeholders
Bickel, Regula, Huber, Beate, Speiser, Bernhard, Urban, Jiri   +3 more
core  

Modification of the existing maximum residue level for pyrimethanil in cucurbits with edible peel

EFSA journal. European Food Safety Authority, 2018
In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant Arysta LifeScience Benelux SPRL submitted a request to the competent national authority in Italy, to modify the existing maximum residue level (MRL) for the active substance ...
Alba Brancato, D. Brocca, Chloé De Lentdecker, Z. Erdős, Lucien Ferreira, Luna Greco, Samira Jarrah, Dimitra Kardassi, R. Leuschner, C. Lythgo, P. Medina, Ileana Miron, Tunde Molnar, A. Nougadère, R. Pedersen, H. Reich, Angela Sacchi, Miguel Santos, A. Stanek, Juergen Sturma, J. Tarazona, A. Theobald, B. Vagenende, A. Verani, Laura Villamar‐Bouza   +24 more
semanticscholar   +1 more source

Function‐driven design of a surrogate interleukin‐2 receptor ligand

FEBS Letters, EarlyView.
Interleukin (IL)‐2 signaling can be achieved and precisely fine‐tuned through the affinity, distance, and orientation of the heterodimeric receptors with their ligands. We designed a biased IL‐2 surrogate ligand that selectively promotes effector T and natural killer cell activation and differentiation. Interleukin (IL) receptors play a pivotal role in
Ziwei Tang, Zelin Cheng, Teng Li, Fulian Wang, Liangminghui Zhang, Xiuxiu He, Lili Liu, Wei Wang, Aibin Liang, Guang Yang   +9 more
wiley   +1 more source

Modification of the existing maximum residue level for tebuconazole in beans with pods

EFSA journal. European Food Safety Authority, 2017
In accordance with Article 6 of Regulation (EC) No 396/2005, the applicant ADAMA Agricultural Solutions Ltd submitted a request to the competent national authority in Denmark to set an import tolerance for the active substance tebuconazole in beans with ...
Alba Brancato, D. Brocca, Chloé De Lentdecker, Z. Erdős, Lucien Ferreira, Luna Greco, Samira Jarrah, Dimitra Kardassi, R. Leuschner, C. Lythgo, P. Medina, Ileana Miron, Tunde Molnar, A. Nougadère, R. Pedersen, H. Reich, Angela Sacchi, Miguel Santos, A. Stanek, Juergen Sturma, J. Tarazona, A. Theobald, B. Vagenende, A. Verani, Laura Villamar‐Bouza   +24 more
semanticscholar   +1 more source