Results 51 to 60 of about 3,900,760 (304)

Structural instability impairs function of the UDP‐xylose synthase 1 Ile181Asn variant associated with short‐stature genetic syndrome in humans

FEBS Letters, EarlyView.
The Ile181Asn variant of human UDP‐xylose synthase (hUXS1), associated with a short‐stature genetic syndrome, has previously been reported as inactive. Our findings demonstrate that Ile181Asn‐hUXS1 retains catalytic activity similar to the wild‐type but exhibits reduced stability, a looser oligomeric state, and an increased tendency to precipitate ...
Tuo Li, Pedro A. Sánchez‐Murcia, Bernd Nidetzky   +2 more
wiley   +1 more source

Organ‐specific redox imbalances in spinal muscular atrophy mice are partially rescued by SMN antisense oligonucleotides

FEBS Letters, EarlyView.
We identified a systemic, progressive loss of protein S‐glutathionylation—detected by nonreducing western blotting—alongside dysregulation of glutathione‐cycle enzymes in both neuronal and peripheral tissues of Taiwanese SMA mice. These alterations were partially rescued by SMN antisense oligonucleotide therapy, revealing persistent redox imbalance as ...
Sofia Vrettou, Brunhilde Wirth
wiley   +1 more source

Impact of desert dust storms, PM10 levels and daily temperature on mortality and emergency department visits due to stroke

Frontiers in Public Health, 2023
ObjectiveIt is known that the inhalation of air pollutants adversely affects human health. These air pollutants originated from natural sources such as desert storms or human activities including traffic, power generating, domestic heating, etc.
M. Murat Oktay, M. Murat Oktay, Behcet Al, Behcet Al, Mustafa Boğan, Mustafa Boğan, Seval Kul, Hasan Gümüşboğa, Hasan Gümüşboğa, Hasan Bayram, Hasan Bayram   +10 more
doaj   +1 more source

Transferrin receptor 1‐mediated iron uptake supports thermogenic activation in human cervical‐derived adipocytes

FEBS Letters, EarlyView.
In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai, Mizuki Seo, Gyath Karadsheh, Fachrur Rizal Mahendra, Máté Á Demény, Ferenc Győry, János András Mótyán, László Fésüs, Endre Kristóf, Rini Arianti   +9 more
wiley   +1 more source

A statistical approach for estimating mean maximum urban temperature excess. [PDF]

, 2003
Munkánkban a városi hősziget (UHI) maximális napi kifejlődését vizsgáltuk Szegeden, a beépítettségi paraméterek függvényében. A hőmérsékleti adatok valamint a beépítettségi arány, a vízfelszín-arány, az égbolt láthatósági index és az épületmagasság ...
Balázs, B., Bottyán, Zsolt, Gál, Tamás Mátyás, Zboray, Z.   +3 more
core  

Short range ferromagnetism and spin glass state in $\mathrm{Y_{0.7}Ca_{0.3}MnO_{3}}$

, 2000
Dynamic magnetic properties of $\mathrm{Y_{0.7}Ca_{0.3}MnO_{3}}$ are reported. The system appears to attain local ferromagnetic order at $T_{\mathrm{SRF}} \approx 70$ K.
A. Moreo, C. Djurberg, D. N. H. Nam, D.N.H. Nam, D.N.H. Nam, D.S. Fisher, E. Vincent, H. Rieger, J. Magnusson, J. Mattsson, J. Mira, J.-O. Andersson, J.M. De Teresa, K. Jonason, L. Lundgren, L. Lundgren, L. Sandlund, N. V. Khiem, N. X. Phuc, P. Granberg, P. Nordblad, P. Nordblad, P. Nordblad, P. Svedlindh, P.-G. de Gennes, P.C. Hohenberg, R. Mathieu, R. Mathieu, X.L. Wang   +28 more
core   +1 more source

Model-based analysis for the thermal management of open-cathode proton exchange membrane fuel cell systems concerning efficiency and stability [PDF]

, 2016
In this work we present a dynamic, control-oriented, concentrated parameter model of an open-cathode proton exchange membrane fuel cell system for the study of stability and efficiency improvement with respect to thermal management.
Costa Castelló, Ramon, Strahl, Stephan
core   +2 more sources

Tau acetylation at K331 has limited impact on tau pathology in vivo

FEBS Letters, EarlyView.
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto, Yukio Matsuba, Mika Takahashi, Takaomi C. Saido   +3 more
wiley   +1 more source

Variáveis ambientais na modelagem do grau de saturação do concreto

Revista IBRACON de Estruturas e Materiais
Com o objetivo de facilitar o cálculo do grau de saturação do concreto, visto que é um fator influente no coeficiente de difusão de íons cloreto no interior do concreto, foram elaborados modelos matemáticos que dispensam medições locais.
M. G. T. Peraça, A. T. C. Guimarães, H. C. Piccoli   +2 more
doaj   +1 more source

Relaxation of a high-energy quasiparticle in a one-dimensional Bose gas

, 2010
We evaluate the relaxation rate of high-energy quasiparticles in a weakly interacting one-dimensional Bose gas. Unlike in higher dimensions, the rate is a nonmonotonic function of temperature, with a maximum at the crossover to the state of suppressed ...
Glazman, Leonid I., Pustilnik, Michael, Tan, Shina   +2 more
core   +1 more source