Diretrizes brasileiras para o tratamento da narcolepsia Brazilian guidelines for the treatment of narcolepsy [PDF]
Este artigo relata as conclusões da reunião de consenso da Associação Brasileira de Sono com médicos especialistas brasileiros sobre o tratamento da narcolepsia, baseado na revisão dos artigos sobre narcolepsia publicados entre 1980 e 2010.
Flávio Alóe +28 more
doaj +6 more sources
Preoperative Management with Mazindol for Obese Women Diagnosed with Endometrial Carcinoma Undergoing Robot-assisted Hysterectomy: A Pilot Case Series and Literature Review [PDF]
Objectives: Obesity poses major perioperative challenges in gynecologic malignancies, particularly endometrial cancer, and increases surgical complexity and risk.
Kuniaki Ota +8 more
doaj +2 more sources
Sex-specific effects of appetite suppressants on stereotypy in rats. [PDF]
This study investigated the sex-specific effects of commonly prescribed appetite suppressants on body weight and the manifestation of motor side effects, specifically stereotypy.
Axl Lopez +2 more
doaj +2 more sources
Consensus Molecules Associated with Parkinson’s Disease [PDF]
Parkinson’s disease (PD) has been associated with some types of food and drugs. Here, we query PubMed for the association of PD with foods and drugs, using a list of 217,776 compounds derived from the Human Metabolome Database (HMDB).
Sara Eyal +12 more
doaj +2 more sources
Occurrence of 97 Pharmaceuticals in Wastewater and Receiving Waters: Analytical Validation and Treatment Influence [PDF]
This study analyzed 97 pharmaceuticals in samples of surface water, as well as influent and effluent from various wastewater treatment plants (WWTPs), during winter 2022 and spring 2023. Approximately 40% of the tested compounds were detected, at amounts
Paula Paíga +6 more
doaj +2 more sources
Mazindol treatment for cocaine dependence
This double-blind placebo-controlled treatment study tested the efficacy of mazindol in currently cocaine-dependent out-patients. Forty-three patients were randomized to mazindol (2 mg QD) vs. placebo treatment for 6 weeks. All patients received weekly group counseling. Patients improved with respect to objective (urine toxicology) and subjective (self-
Susan M Stine
exaly +3 more sources
Therapeutic Effects of Mazindol on Narcolepsy [PDF]
Mazindol, a new anorexiant, was administered at a daily dose of 0.5-4 mg to 10 narcoleptic subjects aged 21-63 years. All the patients suffered from sleep attacks and one or more of the REM-related symptoms. Eight patients received only mazindol, and two patients received mazindol simultaneously with clomipramine or flurazepam.
S, Iijima +3 more
exaly +3 more sources
Over the years, cases of obesity and overweight have grown to epidemic proportions enhancing the consumption of anorectic agents by therapeutic and illegal means. Their consumption is controlled worldwide and can be linked to various adverse effects.
João V.M. de Almeida +5 more
doaj +1 more source
Pharmacological treatment of obesity [PDF]
Overweight and obesity cause many diseases, such as type II diabetes and cardiovascular diseases. Each extra body weight kilogram increases the risk of cancer, including cancer of the oesophagus, kidneys, and pancreas, hepatocellular carcinoma, or cardia
Gabriela Anglart +2 more
doaj +1 more source
Efficacy and safety of the metformin-mazindol anorectic combination in rat
The current study investigates the anorectic interaction and safety of the mazindol-metformin combination in rats. Isobologram and interaction index were used to determine anorectic interaction between mazindol and metformin in the sweetened milk model ...
Argüelles-Tello Federico +7 more
doaj +1 more source

