Results 31 to 40 of about 481,129 (243)
Granuloma formation in pulmonary sarcoidosis
Frontiers in Immunology, 2013 Sarcoidosis is a granulomatous disorder of unknown cause, affecting multiple organs, but mainly the lungs. The exact order of immunological events remains obscure.
Caroline E. Broos +5 more
doaj +1 more source
Archivos de Prevención de Riesgos Laborales, 2020 Objetivo: Describir la evolución temporal (2009-2018) de la incidencia de la incapacidad temporal por contingencia común (ITCC) según tramos de duración en España.
Mónica Ballesteros Polo +9 more
doaj +1 more source
Molecular Oncology, EarlyView.We developed a cost‐effective methylation‐specific droplet digital PCR multiplex assay containing tissue‐conserved and tumor‐specific methylation markers. The assay can detect circulating tumor DNA with high accuracy in patients with localized and metastatic colorectal cancer.
Luisa Matos do Canto +8 more
wiley +1 more source
The status of nomination forms and wills when retirement funds’ death benefits are distributed
De Jure, 2023 This paper discusses the importance of deceased retirement fund members nominating their preferred beneficiaries to receive their accumulated retirement benefits when they die.
Motseotsile Clement Marumoagae
doaj
Frontiers in Cellular Neuroscience, 2015 Defects in the rat sarcoma viral oncogene homolog (Ras)/extracellular-signal-regulated kinase (ERK) and the phosphatidylinositol 3-kinase (PI3K)-mammalian target of rapamycin (mTOR) signaling pathways are responsible for several neurodevelopmental ...
Tiantian eWang +5 more
doaj +1 more source
Local myocardial stiffness variations identified by high frame rate shear wave echocardiography
Cardiovascular Ultrasound, 2020 Background Shear waves are generated by the closure of the heart valves. Significant differences in shear wave velocity have been found recently between normal myocardium and disease models of diffusely increased muscle stiffness.
Mihai Strachinaru +7 more
doaj +1 more source
Effective therapeutic targeting of CTNNB1‐mutant hepatoblastoma with WNTinib
Molecular Oncology, EarlyView.WNTinib, a Wnt/CTNNB1 inhibitor, was tested in hepatoblastoma (HB) experimental models. It delayed tumor growth and improved survival in CTNNB1‐mutant in vivo models. In organoids, WNTinib outperformed cisplatin and showed enhanced efficacy in combination therapy, supporting its potential as a targeted treatment for CTNNB1‐mutated HB.
Ugne Balaseviciute +17 more
wiley +1 more source
Are We Underestimating Benthic Cyanotoxins? Extensive Sampling Results from Spain
Toxins, 2017 Microcystins (MCs) are potent hepatotoxins, and their presence in water bodies poses a threat to wildlife and human populations. Most of the available information refers to plankton, and much less is known about microcystins in other habitats. To broaden
Enrique A. Cantoral Uriza +2 more
doaj +1 more source
Molecular Oncology, EarlyView.Pharmacologic ascorbate (vitamin C) increases ROS, disrupts cellular metabolism, and induces DNA damage in CRPC cells. These effects sensitize tumors to PARP inhibition, producing synergistic growth suppression with olaparib in vitro and significantly delayed tumor progression in vivo. Pyruvate rescue confirms ROS‐dependent activity.
Nicolas Gordon +13 more
wiley +1 more source
von Willebrand Factor is elevated in HIV patients with a history of thrombosis
Frontiers in Microbiology, 2015 BackgroundArterial and venous thrombotic events are more prevalent in HIV infected individuals compared to the general population, even in the era of combination antiretroviral therapy.
Lennert W.J. van den Dries +7 more
doaj +1 more source