Results 91 to 100 of about 3,283 (203)

Quaternary structures of Streptococcus pneumoniae nucleoside diphosphate kinase: From hexamers to supramolecular assemblies

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract The nucleoside diphosphate kinase (NDK) is a key enzyme that controls the balance of nucleotide pools in all living organisms. Beyond this fundamental role, NDKs exert pleiotropic effects in many cellular processes, including cell development, signal transduction, differentiation, tumor metastasis, and gene expression. The quaternary structure
Julie Kerboeuf   +10 more
wiley   +1 more source

A prodrug strategy for sustained release of lactic acid from silicone elastomer vaginal rings. [PDF]

open access: yesInt J Pharm
Dallal Bashi YH   +17 more
europepmc   +1 more source

Total synthesis and structural characterization of a novel protein scaffold from the snail Biomphalaria glabrata

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Disulfide‐rich miniproteins constitute compact and highly stable scaffolds of growing interest for molecular and structural engineering. Schistosomins are ~80‐residue proteins conserved across gastropods that form a long‐standing orphan family whose structure and biological roles have remained unknown.
Oleg Melnyk   +13 more
wiley   +1 more source

Past Colony Connectivity of a Declining Seabird Derived From Host-Parasite Genetic Data. [PDF]

open access: yesEcol Evol
Cargill CP   +6 more
europepmc   +1 more source

A cryptic allosteric pocket shapes isoform‐selective inhibition of human malic enzymes

open access: yesProtein Science, Volume 35, Issue 9, September 2026.
Abstract Malic enzymes (ME) regulate central carbon metabolism and cellular redox balance, and the mitochondrial isoform ME2 is frequently upregulated in aggressive cancers to support metabolic flexibility and stress resistance. Isoform‐selective inhibition has remained out of reach because the catalytic machinery is essentially invariant across the ...
Ben A. Krinkel   +14 more
wiley   +1 more source

A framework for characterising and capturing the quality of digital interactions and experiences in early childhood education

open access: yesBritish Journal of Educational Technology, Volume 57, Issue 5, Page 1299-1319, September 2026.
Abstract Understanding what constitutes quality in digital interactions within Early Childhood Education and Care (ECEC) settings has become paramount in an increasingly technology‐enabled world. This imperative has grown, with diverse ingrained positions about the role of digital technology in ECEC, and limited evidence and guidance to support ...
Steven J. Howard   +4 more
wiley   +1 more source

Intra‐Individual Variability in Children's Self‐Regulation in Kindergarten Classrooms: An Observational Study

open access: yesDevelopmental Science, Volume 29, Issue 5, September 2026.
ABSTRACT Children's ability to self‐regulate varies across days and contextual demands. However, the predominant approach in developmental science is to assess self‐regulation at a single timepoint in one context, limiting our understanding of how and why children's self‐regulation skills vary intra‐ and inter‐individually.
Nora Tilda Kunz, Niamh Oeri
wiley   +1 more source

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