Results 131 to 140 of about 124,045 (313)

Mechanisms of Mitochondrial Toxicity and Cytotoxicity Caused by Pseudomonas aeruginosa Pyocyanin in Human Nasal Epithelial Cells

International Forum of Allergy &Rhinology, EarlyView.
ABSTRACT Background Pseudomonas aeruginosa is an opportunistic pathogen in cystic fibrosis‐related chronic rhinosinusitis (CF‐CRS) that produces phenazine metabolites pyocyanin and 1‐hydroxyphenazine (1‐HP), which may have detrimental effects on mitochondria, reactive oxygen species (ROS), Ca2+ signaling, and apoptosis.
Joel C. Thompson, April Park, Yobouet Ines Kouakou, Zoey A. Miller, Nabil F. Darwich, Nithin D. Adappa, James N. Palmer, Ryan M. Carey, Robert J. Lee   +8 more
wiley   +1 more source

3D Hydrogel Cell Cultures and Their Biomedical Applications

Advanced NanoBiomed Research, EarlyView.
The review highlights the advantages of hydrogel‐based 3D cell cultures over traditional 2D models. These hydrogels closely mimic natural cellular environments, improving research in tissue engineering, drug discovery, cancer studies, and neuroscience.
Tri Lan Thai, Arushi Manchanda, Sarah L. Higginbottom, Estrella Sanz Rodriguez, Richard Wilson, Eva Tomaskovic‐Crook, Jeremy M. Crook, Brett Paull   +7 more
wiley   +1 more source

Synthesis and Characterization of Brucine Gold Nanoparticles for Targeted Breast Cancer Therapy: Mechanistic Insights into Apoptosis and Antioxidant Disruption in MCF‐7 Cells [PDF]

Saravanan Alamelu, Kamalesh Balakumar Venkatesan, Manoj Kumar Srinivasan, Pachaiappan Pugalendhi   +3 more
openalex   +1 more source

Surface‐Coated Inorganic Nanomaterials for Drug Delivery: Chemical Design, Biomedical Applications, and Mechanistic Insights

Advanced NanoBiomed Research, EarlyView.
This review explores how surface‐coated inorganic nanomaterials are chemically engineered for advanced drug delivery. It highlights design principles, coating strategies, and biomedical applications, emphasizing how surface chemistry governs biocompatibility, targeting, and controlled release.
Hossein Daneshgar, Sepideh Ahmadi, Nikzad Abbariki, Navid Rabiee, Sidi A. Bencherif   +4 more
wiley   +1 more source

The cellular uptake mechanism, intracellular transportation, and exocytosis of polyamidoamine dendrimers in multidrug-resistant breast cancer cells

International Journal of Nanomedicine, 2016
Jie Zhang,1 Dan Liu,1 Mengjun Zhang,1 Yuqi Sun,1,2 Xiaojun Zhang,1 Guannan Guan,1 Xiuli Zhao,1 Mingxi Qiao,1 Dawei Chen,1 Haiyang Hu1 1Department of Pharmaceutics, School of Pharmacy, Shenyang Pharmaceutical University, Shenyang, 2Department of ...
Zhang J, Liu D, Zhang MJ, Sun YQ, Zhang XJ, Guan GN, Zhao XL, Qiao MX, Chen DW, Hu HY   +9 more
doaj  

Exploring CDKN1A Upregulation Mechanisms: Insights into Cell Cycle Arrest Induced by NC2603 Curcumin Analog in MCF-7 Breast Cancer Cells [PDF]

Felipe Garcia Nishimura, Beatriz Borsani Sampaio, Tatiana Takahasi Komoto, Wanessa Julia da Silva, Mariana Mezencio Gregório da Costa, Gabriela Inforçatti Haddad, Kamila Chagas Peronni, Adriane Feijó Evangelista, Mohammad Hossain, Jonathan R. Dimmock, Brian Bandy, René Oliveira Beleboni, Mozart Marins, Ana Lúcia Fachin   +13 more
openalex   +1 more source

Anticancer effect of Illicium verum (star anise fruit) against human breast cancer MCF-7 cell line

, 2022
Asra Khan Pahore, Shagufta Khan, Nasim Karim   +2 more
openalex   +2 more sources

Anticancer potential of ethanolic sidr leaf extracts against MCF-7 breast cancer cells: phytochemical, nutritional, and antimicrobial profile comparisons of different plant parts [PDF]

Roqayah H. Kadi, Nashi K. Alqahtani, Ahmed M. Abdulfattah, Fayez Alsulaimani, Ahmed M. Basri, Reham M. Algheshairy, Hend F. Alharbi, Rokayya Sami, Amal Alyamani, Roua S. Baty, Ruqaiah I. Bedaiwi, Hala M. Abo-Dief, Nahid A. Osman, Nouf H. Alsubhi, Ashwaq M. Al-Nazawi, Manal Malibary   +15 more
openalex   +1 more source

Histology and fossil diagenesis of a pterosaur tooth from the Crato Formation (Lower Cretaceous of Brazil)

The Anatomical Record, EarlyView.
Abstract Pterosaur dental biology remains poorly understood despite its importance for comprehending feeding strategies and flight adaptations. Here, we present the first comprehensive histological analysis of an ornithocheiriform pterosaur tooth from the Lower Cretaceous Crato Formation (Santana Group, Northeast Brazil).
Tito Aureliano, Matheus P. S. Rocha, Francisco P. Lima‐Filho, Aline M. Ghilardi   +3 more
wiley   +1 more source

Comparative cranial biomechanics reveal macroevolutionary trends in theropod dinosaurs, with emphasis on Tyrannosauroidea

The Anatomical Record, EarlyView.
Abstract Tyrannosaurus is viewed as a model organism in vertebrate paleontology, with numerous studies analyzing its feeding biomechanics. Nonetheless, the evolution of this feeding performance has been under‐addressed in Tyrannosauroidea, especially in basal tyrannosauroids. Here we used muscle‐force reconstruction and finite element analysis (FEA) to
Evan Johnson‐Ransom, Paul Gignac, Daniel E. Barta, Ryan N. Felice, Eric Snively   +4 more
wiley   +1 more source