Results 171 to 180 of about 114,577 (260)

Gene Therapy for Amino Acid Decarboxylase Deficiency: Clinical and Imaging Outcomes in a French Cohort

Movement Disorders, EarlyView.
Abstract Background Intracerebral gene therapy is effective for amino acid decarboxylase (AADC) deficiency, but relationships between anatomical putaminal coverage, metabolic dynamics, and clinical recovery remain poorly understood. Objectives Assess safety, long‐term efficacy, and clinical–radiological correlations in a genetically diverse European ...
Clément Dunoyer, Gaëtan Poulen, Marie‐Céline François‐Heude, Eline Chauvet‐Piat, Bérénice Lecardonnel, Emmanuel Roze, Marie‐Ange Nguyen Morel, Domitille Gras, Adeline Quintard, Gaelle Baroux, Pierre Meyer, Philippe Coubes, Christophe Milesi, Julien Baleine, Chrystelle Sola, Vivien Szabo, Bénédicte Delye, Jana Haberlova, Mohamed Osman Eltahir Babiker, Mohammed Al Muqbil, Stéphanie Sanchez, Souad Touati, Nicolas Leboucq, Virginie Kouyoumdjian, Sylvia Sanquer, Denis Mariano‐Goulart, Thomas Roujeau, Agathe Roubertie   +27 more
wiley   +1 more source

Synthesis and cytotoxicity of novel cyanochalcones: induction of cell cycle arrest, apoptosis, and autophagy in HEP2 and MCF-7 cells. [PDF]

Naunyn Schmiedebergs Arch Pharmacol
Ibrahim NS, WalyEldeen AA, Ibrahim SA, Abdelhamid IA, Elhakim HKA.   +4 more
europepmc   +1 more source

Hsp90 Inhibition on the Western Blot: N‐Terminal Versus C‐Terminal Inhibitors in Breast Cancer

Medicinal Research Reviews, EarlyView.
ABSTRACT Heat shock protein 90 (Hsp90) is an established and clinically validated anticancer target. By regulating the folding and maturation of diverse client proteins, it is indirectly involved in carcinogenesis. Key breast cancer oncogenic drivers, including estrogen receptor, progesterone receptor, and human epidermal growth factor receptor 2, are ...
Jaka Dernovšek, Jernej Cingl, Urša Pečar Fonović, Tihomir Tomašič   +3 more
wiley   +1 more source

Effects of Polysaccharide Coating on Cell-Surface Association and Endocytic Uptake of PLGA Nanomicelles in MCF-7 Cells. [PDF]

Pharmaceutics
Alkan AB, Develi Arslanhan EN, Bahadori F, Kasapoglu MZ, Akbas F, Susgun S, Eskandari Z, Oner ET.   +7 more
europepmc   +1 more source

An Extended Formulation With Valid Inequalities for the Capacitated Steiner Arborescence Problem

Networks, EarlyView.
ABSTRACT Given a directed graph, the Capacitated Steiner Arborescence Problem (CSAP) aims to determine the least‐cost connection from the root node to terminal nodes requiring a demand through Steiner nodes coming with a capacity, such that there is a unique path from the root to each terminal. This paper presents a new extended formulation of the CSAP,
Francesco Contu, Massimo Di Francesco, Enrico Gorgone, Ishwar Murthy   +3 more
wiley   +1 more source

Evaluation of silver nitroprusside nanoparticles: selective toxicity against MCF-7 cells and in vivo antitumor activity. [PDF]

Discov Nano
Fernandes DS, Jayme CC, Matsuo FS, de Lima SCG, Fantacini DMC, de Souza LEB, Tedesco AC.   +6 more
europepmc   +1 more source

Hybrid Metal‐Coated Carbon Fiber/Multi‐Walled Carbon Nanotube Networks for Enhanced Electrical and Mechanical Performance

Polymer Composites, EarlyView.
Multifunctional enhancement of metal‐coated carbon fiber/multi‐walled carbon nanotube hybrid composites fabricated by injection molding. ABSTRACT As electronic devices and components continue to become more powerful and highly integrated, there is an increasing demand for lightweight, cost‐effective, and easy‐to‐process conductive materials.
Min Su Kim, Bo‐Kyung Choi, Ki Hoon Kim, Ji‐Hun Kang, Chaewook Jo, Jong‐Hyun Park, Seong Yun Kim   +6 more
wiley   +1 more source

Synergistic Potential of Organotin(IV) Carbodithioate Derivatives with Vitamins D and E in MCF-7 and MDA-MB-231 Breast Cancer Cells. [PDF]

Pharmaceuticals (Basel)
Kanwal B, Shaheen F, Shah SS, Cheema Y, Ali S, Hanif R.   +5 more
europepmc   +1 more source