Results 221 to 230 of about 7,687,713 (299)

Breast-Cancer-Derived Secretomes from MCF-7 Cells Modulate Bacterial Pathogenic Traits. [PDF]

Int J Mol Sci
Mahmood SM, Al-Nasrallah HK, Aldossry A, Al-Ansari MM, Al-Alwan M.   +4 more
europepmc   +1 more source

Harnessing the Folding of Antitumor Peptides for Controlled Carrier‐Free Drug Delivery

Small, EarlyView.
A disulfide‐bridged stapled p53 α‐helix co‐assembled with doxorubicin into protease‐resistant nanocomplexes. Reductive intracellular conditions induced helix refolding and nanostructure disassembly, which enabled the coordinated release of the chemotherapeutic agent and anticancer peptide.
Jae Yun Lee, Moo Chang Park, Sung Chan Choi, Jieun Kim, Joo‐young Kim, Jiah Lee, Hyun Jin Kim, Kyobum Kim, Yongju Kim, Woo‐jin Jeong   +9 more
wiley   +1 more source

Retraction Note: Dual role of ROS-dependent anti-cancer activity and photocatalytic degradation of graphene oxide against MCF-7 breast cancer cells and organic dye. [PDF]

Sci Rep
Chelliah CK, Rajivgandhi G, Maruthupandy M, Chackaravarthi G, Ramachandran G, Liu YH, Mohamad OAA, Li S, Li WJ, Bhaviripudi VR, Basha SS, Shahapurkar K, Gebremaryam G.   +12 more
europepmc   +1 more source

HER2‐Targeted AIE Nanotheranostics Overcome SHR‐A1811 Resistance via Immunogenic Pyroptosis and Tumor‐Associated Macrophage Reprogramming in Breast Cancer

Small, EarlyView.
HER2‐targeted AIE780‐A1811 nanoparticles self‐assemble via amide coupling of a mitochondria‐directed photosensitizer with the ADC SHR‐A1811. Upon 660 nm irradiation, they generate ROS, photothermal effects, and controlled drug release, inducing immunogenic pyroptosis and M2‐to‐M1 macrophage reprogramming. This dual action remodels the immunosuppressive
Xiaohong Liu, Nisha Wu, Zaihui Peng, Guozhi Zhang, Lin Ren, Qiuyun Li, Jie Xiao, Jing He, Yuxiuzi Xiao, Li Ma, Yi Zhang, Ying Gong, Xiaowei Qi   +12 more
wiley   +1 more source

Evaluation of the Cytotoxic Effects of <i>Odontobuthus doriae</i> Crude Venom on the MCF-7 Breast Cancer Cell Line. [PDF]

J Arthropod Borne Dis
Tashakori G, Mohammadpour-Dounighi N, Akhavan AA, Basseri HR, Abdi K, Tofighi-Zavareh F, Khorasani S, Fatemi M, Biglarian A, Saboor-Yaraghi AA, Rafinejad J.   +10 more
europepmc   +1 more source

Tailored Molecular Scissor Unlocks the Autocatalytic Potential of Hybridization Chain Reaction for Tunable Signal Amplification

Small, EarlyView.
We establish a recycling chain reaction (RCR) using a single hairpin, H3, which disassembles HCR assemblies to unlock the inherent autocatalytic potential of HCR. Conventional HCR is redefined as the fully constrained state (H3 = 0) of RCR. Tuning H3 ratios enables dynamic control over DNA assembly, providing a compact platform for biomolecular ...
Ting Li, Kaiqi Hu, Jiaying Li, Ying Yi Lee, Kin Ming Kwan, Hung‐Wing Li   +5 more
wiley   +1 more source

Development of a Breast-on-a-Chip Microfluidic Model to Assess the Effect of Palbociclib in MCF-7 and T47D Cancer Cells. [PDF]

Cells
Souza ILM, Gomes Torres ACMB, Lucas R, Jiacomini IG, Klein SR, E Reis MB, Suzukawa AA, Zanette DL, Aoki MN, de Aguiar AM, Dallagiovanna B, Blanes L.   +11 more
europepmc   +1 more source

Enhanced through‐bond energy transfer‐based bioorthogonal probe enables catalytic‐amplified and sensitive detection of microRNA‐21 for clinical lung cancer diagnosis

Smart Molecules, EarlyView.
Inverse Diels‐Alder Cycloaddition Reaction was developed for ultrasensitive miR‐21 detection. Based on the enhanced Through‐Bond Energy Transfer and catalytic amplification, it shows a detection limit of 3.58 × 10−18 M and 100 aM–100 nM linear range. It enables high‐contrast cell/tissue imaging and distinguishes lung cancer patients in serum, promising
Yikun Li, Fuping Han, Haiqiao Huang, Danhong Zhou, Saran Long, Wen Sun, Jianjun Du, Jiangli Fan, Jing Ning, Chong Peng, Xiaojun Peng   +10 more
wiley   +1 more source

In-vitro pharmacological and cytotoxic evaluation of genipin-crosslinked human serum albumin nanoparticles loaded with methyltestosterone in MCF-7 breast cancer cells. [PDF]

BMC Pharmacol Toxicol
Ganji E, Heydari M, Arminfar A, Mirzaei M.   +3 more
europepmc   +1 more source

A lysosomal escape‐enabled endoplasmic reticulum‐targeting BODIPY photothermal agent for enhanced tumor ablation

Smart Molecules, EarlyView.
To advance precision cancer therapy, we engineered ER‐BDP NPs, a self‐assembled nanomedicine designed for selective ER localization. By integrating organelle targeting with localized laser activation, this agent mediates precision‐guided tumor destruction in vitro and in vivo while reducing off‐target effects, effectively balancing therapeutic efficacy
Shaoyang Shi, Yanbing Cao, Jiexuan Zuo, Qiushi Li, Xiaolong Zeng, Jianjun Du, Jiangli Fan, Wen Sun, Xiaojun Peng   +8 more
wiley   +1 more source