Results 231 to 240 of about 7,687,713 (299)

Antioxidant, antimicrobial, and apoptosis-related activities of Azadirachta indica (Neem) leaf extract in MCF-7 and A549 cell lines. [PDF]

Sci Rep
Toson EA, Marzouk M, Rezk NA, Rabei S, Zahran RF.   +4 more
europepmc   +1 more source

Stimuli‐responsive nanostructured hydrogen sulfide donors for enhanced cancer treatments

Smart Molecules, EarlyView.
Three typical kinds of stimuli‐responsive nanostructured hydrogen sulfide (H2S) donors are reviewed. The nanostructures ensure precise delivery of H2S to the lesion site and regulate the release behavior. The H2S‐based gas therapy has been used to synergize with other cancer treatment modalities, achieving enhanced efficacy while reducing side effects.
Yuxuan Lyu, Jiaxuan Zhu, Lei Lei, Qingyang Zhong, Zhao Li, Caihong Lei, Fan Rong, Yin Wang   +7 more
wiley   +1 more source

Metal thiosemicarbazonates as dual mR2 RNR and colchicine-site tubulin inhibitors: from biochemical inhibition to mitotic arrest in MCF-7 breast cancer cells.

Inorg Chem Front
Palamarciuc O, Ciubotaru BI, Stoica AC, Hejl M, Hammerstad M, Balan-Porcarasu M, Shova S, Gátszegi GT, Popović Bijelić A, Reynisson J, Jakupec MA, Zalibera M, Rapta P, Enyedy ÉA, Peptanariu D, Dascalu M, Cazacu M, Hamel E, Arion VB.   +18 more
europepmc   +1 more source

Bio-functional and anti-cancer (MCF-7) benzyl isothiocyanate nanoemulsions preparation using green pressurized water and process optimization. [PDF]

Sci Rep
Rezaei A, Ebrahimiasl S, Jafarizadeh-Malmiri H.   +2 more
europepmc   +1 more source

Photostabilized halocyanine for near‐infrared excited bimodal photothermal synergism and tumor‐targeted therapy

Smart Molecules, EarlyView.
A series of halogenated organic small molecules were prepared by substituting hydrogen atoms in BC7 molecules with halogen atoms. These chemically modified derivatives displayed significantly improved stability, warming efficiency, and reactive oxygen species generation ability. BC7‐Br and BC7‐Cl showed remarkably enhanced therapeutic efficacy relative
Zongjin Qu, Yurong Guo, Cuixia Yao, Can Wang, Zhen Wang, Jiali Li, Zhao Wang, Yingying Jing, Yen Leng Pak, Xing Gao, Shusheng Zhang   +10 more
wiley   +1 more source

Preclinical antitumor evaluation of a tetrahydrocannabinol and cannabidiol (1:6) cannabis extract in an MCF-7 xenograft model of estrogen receptor-positive breast cancer. [PDF]

Vet World
Meesiripan N, Thanasitthichai S, Sangrajrang S, Suwanpidokkul N, Prayakprom P, Bodhibukkana C, Khaowroongrueng V, Suriyachan K, Srisubat A, Surawongsin P, Rattanapinyopituk K, Sakarin S.   +11 more
europepmc   +1 more source

Artificial intelligence empowers targeted protein degradation: Core technological innovations, multi‐scenario applications, and translational prospects

Smart Molecules, EarlyView.
AI is transforming TPD by improving the design, prediction, and optimization of degraders such as PROTACs, molecular glues, and LYTACs. This review summarizes key AI‐driven advances, highlights applications across drug discovery stages, and discusses remaining challenges and future directions for accelerating the development of therapies against ...
Shuanglin Qin, Rui Peng, Guangshuai Zhang, Si Yan, Jin Xiao, Zishu Liu, Ziyu Tan, Qingqing Xie, Shangjie Li, Wei Luo, Xiaohe Xiao   +10 more
wiley   +1 more source

Comparative evaluation of the effects of Silymarin on the metastatic characteristics of MCF-7 and MDA-MB-231 breast cancer cells with two-dimensional and three-dimensional culture methods. [PDF]

BMC Complement Med Ther
Aladağ T, Firat F, Çetin H, Arikan Söylemez ES.   +3 more
europepmc   +1 more source

Advances in research on layered double hydroxides for biomedical applications

Smart Molecules, EarlyView.
Layered double hydroxides (LDHs) are pH‐responsive nanomaterials with broad biomedical applications. This review summarizes LDH synthesis methods and compares their advantages. It highlights LDHs' progress in cancer therapy, including chemo‐photothermal, chemo‐immunotherapy, and photodynamic‐immunotherapy combinations and their potential in bone repair.
Xinhui Yang, Zhiping Zhang, Zhao Wang, Hao Zhang, Yen Leng Pak, Yingying Jing, Yurong Guo, Fang Li, Xiao Wang, Quanxiang Han, Lei Yu, Xuejiao Li, Xing Gao, Jibin Song   +13 more
wiley   +1 more source

Novel Selective Anticancer Effect of Epididymis-Derived Extracellular Vesicles Against HCC38 and MCF-7 Breast Cancer Cell Lines. [PDF]

Int J Mol Sci
Zoabi R, Ali Saleh Z, Issaq E, Morad E, Miari R, Taha H, Kadriya A, Samson AO, Falah M.   +8 more
europepmc   +1 more source