Results 141 to 150 of about 2,161 (168)
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LT and SOX9 expression are associated with gene sets that distinguish Merkel cell polyomavirus (MCPyV)-positive and MCPyV-negative Merkel cell carcinoma

British Journal of Dermatology
Abstract Background Merkel cell carcinoma (MCC) is an aggressive malignant neuroendocrine tumour. There are two subsets of MCC, one related to Merkel cell polyomavirus (MCPyV) and the other to ultraviolet radiation (UVR).
Juan Torre-Castro   +12 more
openaire   +2 more sources

Detection of human polyomaviruses MCPyV, HPyV6, and HPyV7 in malignant and non‐malignant tonsillar tissues

Journal of Medical Virology, 2015
Merkel cell polyomavirus (MCPyV) is associated with Merkel cell carcinoma (MCC), a rare skin malignancy. Human polyomavirus six and seven (HPyV6 and HPyV7) were identified on a skin but have not been associated with any pathology. The serology data suggest that infection with polyomaviruses occurs in childhood and they are widespread in population ...
Martina, Saláková   +4 more
openaire   +2 more sources

Significant overexpression of the Merkel cell polyomavirus (MCPyV) large T antigen in Merkel cell carcinoma

Head & Neck, 2012
AbstractBackgroundThe purpose of this study was to determine the expression pattern of the Merkel cell polyomavirus (MCPyV) large T‐protein antigen in patients with Merkel cell carcinoma.MethodsA tissue microarray (TMA) containing 30 specimens was constructed and stained for the MCPyV large T protein.
Boban M, Erovic   +5 more
openaire   +2 more sources

Whole genome sequencing elucidates etiological differences in MCPyV-negative Merkel cell carcinoma

Pathology - Research and Practice
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine neoplasm of the skin. Immunosuppression, ultraviolet radiation and the integration of Merkel cell polyomavirus (MCPyV) have all been shown to be involved in the pathogenesis of this malignancy.
Carla, Stephan   +9 more
openaire   +2 more sources

Charakterizace imunitní odpovědi proti lidskému polyomaviru MCPyV.

2013
Characterization of immune responses to human polyomavirus MCPyV There have been considerable increase in number of known human polyomaviruses in recent years; currently we register twelve of them. Presumably, majority of human polyomaviruses cause lifelong persistent infection. Primary infection is usually asymptomatic and is followed by appearance of
openaire   +1 more source

Replikace polyomaviru Merkelových buněk (MCPyV) v lidských buněčných kulturách

2022
The Merkel cell polyomavirus (MCPyV) is the only human polyomavirus classified as probably carcinogenic to humans and is the causal factor of a rare aggressive skin malignancy the Merkel cell carcinoma (MCC) in around 80% of cases. Nevertheless, in addition to skin the virus was detected in various body tissues. In spite of that an ideal in vitro model
openaire   +1 more source

Seroprevalence rates of BKV, JCV, and MCPyV polyomaviruses in the general Czech Republic population.

Journal of medical virology, 2015
JC and BK polyomaviruses (JCV and BKV) infect humans and can cause severe illnesses in immunocompromised patients. Merkel cell polyomavirus (MCPyV) can be found in skin carcinomas. In this study, we assessed the occurrence of serum antibodies against MCPyV, BKV, and JCV polyomaviruses in a healthy population of the Czech Republic.
Vojtěch, Sroller   +9 more
openaire   +1 more source

The roles of MCPyV early region in IL-17A-mediated inflammation and autophagy

Les rôles de la région précoce de MCPyV dans l'inflammation médiée par l'IL-17A et l'autophagie Le carcinome à cellules de Merkel (MCC) est une tumeur maligne cutanée agressive et rare qui touche principalement les patients âgés et immunodéprimés. Le polyomavirus à cellules de Merkel (MCPyV) est l'agent étiologique du 80 % de MCC , dont
openaire   +1 more source

Structural Analysis of Merkel Cell Polyomavirus (MCPyV) Viral Capsid Protein 1 (VP1) in HIV-1 Infected Individuals

International Journal of Molecular Sciences, 2020
Valeria Pietropaolo   +2 more
exaly  

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