Inhibitory Immune Checkpoints beyond Programmed Cell Death Ligand 1 in Merkel Cell Carcinoma: Abundant Expression of TIGIT Independent of the Presence of Merkel Cell Polyoma Virus. [PDF]
Toberer F +8 more
europepmc +1 more source
Rare Merkel cell carcinoma cardiac involvement: A case of cystic metastasis to the left heart. [PDF]
Kazmi A +8 more
europepmc +1 more source
IFN γ and the IFN γ Signaling Pathways in Merkel Cell Carcinoma. [PDF]
Song L +5 more
europepmc +1 more source
Tertiary lymphoid structures in Merkel cell carcinoma facilitate naïve and central memory T-cell infiltration linked to immunotherapy response. [PDF]
Srinivas N +17 more
europepmc +1 more source
Late Metastatic Recurrence of Merkel Cell Carcinoma Nine Years After the Primary Diagnosis. [PDF]
Kubicki SL +4 more
europepmc +1 more source
Merkel Cell Polyomavirus (MCPyV) and Cancers: Emergency Bell or False Alarm?
Merkel cell polyomavirus (MCPyV), the sole member of Polyomavirus associated with oncogenesis in humans, is the major causative factor of Merkel cell carcinoma (MCC), a rare, neuroendocrine neoplasia of the skin. Many aspects of MCPyV biology and oncogenic mechanisms remain poorly understood.
George Sourvinos, Sourvinos George
exaly +4 more sources
Human polyomaviruses JCPyV and MCPyV in urothelial cell carcinoma: a single institution experience
ObjectiveUrothelial cell carcinoma (UCC) is the most common type of urinary bladder. JCPyV and BKPyV have been detected in the urine and tissue of urothelial cell carcinomas (UCC) in immunocompetent patients. Here, we investigated the presence of several HPyVs in UCC samples using diverse molecular techniques to study the prevalence of HPyVs in UCC ...
Faisal Klufah +2 more
exaly +4 more sources
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In Vitro Replication Assay for Merkel Cell Polyomavirus (MCPyV)
Current Protocols in Microbiology, 2015AbstractMerkel cell polyomavirus (MCPyV) genomes are clonally integrated in tumor cells of ∼95% of all Merkel cell carcinoma (MCC) cases. The virus is highly prevalent; however, where the virus persists and which cell types are permissive for MCPyV replication is still unknown. As a consequence, very little information is available about the life cycle
Manja Czech-Sioli +2 more
exaly +3 more sources
The new polyomavirus (MCPyV) does not affect the clinical course in MCCs
International Journal of Oral and Maxillofacial Surgery, 2010Since 2008, a new polyomavirus (MCPyV) in Merkel cell carcinomas (MCC) has been described, but little is known about its impact on the clinical course. The purpose of this study was to determine the presence of MCPyV in a large sample and to correlate the results with the clinical course of the disease. 59 samples from 44 patients were analysed for the
J Handschel +2 more
exaly +3 more sources

