Results 171 to 180 of about 3,812 (207)

Immunoglobulin Expressions Are Only Associated With MCPyV-positive Merkel Cell Carcinomas But Not With MCPyV-negative Ones

American Journal of Surgical Pathology, 2014
Merkel cell carcinoma (MCC) is an aggressive neuroendocrine skin cancer, often associated with Merkel cell polyomavirus (MCPyV). Recently, immunoglobulin (Ig) expression was reported in MCC, thereby suggesting that B cells might be their cellular ancestors.
Ichiro Murakami, Katsuyoshi TAkata, Michiko Matsushita   +2 more
exaly   +3 more sources

Merkel cell polyomavirus (MCPyV) strains in Japanese merkel cell carcinomas (MCC) are distinct from Caucasian type MCPyVs: genetic variability and phylogeny of MCPyV genomes obtained from Japanese MCPyV-infected MCCs

Virus Genes, 2013
Most of merkel cell carcinomas (MCC), a rare, aggressive skin cancer with neuroendocrine features, harbor merkel cell polyomavirus (MCPyV). Seroepidemiological studies suggested high prevalence of MCPyV in the human population. More than ten sequence data on MCPyV strains in Japan have been available, whereas most sequence data were detected from ...
Michiko Matsushita, Takeshi Iwasaki, Satoshi Kuwamoto   +2 more
exaly   +3 more sources

Merkel cell polyomavirus (MCPyV) DNA prevalence in Brazilian blood donors

Transfusion Clinique Et Biologique, 2023
Merkel cell polyomavirus (MCPyV) is an oncogenic virus that has been etiologically linked to Merkel cell carcinoma. Low levels of MCPyV DNA have been detected in blood donors with unclear impact on transfusion. The prevalence of MCPyV DNA in Brazilian blood donors is unclear.
Victoria Simionatto, Zucherato, Perícles Natan Mendes, da Costa, Marta, Giovanetti, Luciana Maria Fontanari, Krause, Daiani Cristina Cilião, Alves, Renata Maria Alencar, Moreira, Barbara Maciel Sidou, Pimentel, Rodrigo, Haddad, Hellen Tayaná, Bitencourt, Massimo, Ciccozzi, Luiz Carlos Júnior, Alcantara, Simone, Kashima, Dimas Tadeu, Covas, Svetoslav Nanev, Slavov   +13 more
exaly   +3 more sources

MCPyV-Negative Merkel Cell Carcinoma In Situ Associated With Immunosuppression

The American Journal of Dermatopathology, 2023
Abstract: Merkel cell carcinoma (MCC) is a rare and aggressive cutaneous neoplasm that is almost always intradermal. Immunosuppression increases the risk of MCC, which is believed to be due to increased susceptibility to Merkel cell polyomavirus (MCPyV). Intraepidermal MCC, or MCC in situ (MCCis), is extremely rare and usually associated with
Anika, Mazumder, Pooria, Khoshnoodi, Jessica, Gruber, Nicole M, Burkemper   +3 more
openaire   +2 more sources

Merkel Cell Polyomavirus (MCPyV)

2020
No abstract available.
Sofia, Asioli, Ricci, Costantino
openaire   +2 more sources

31 MCPyV and the immune system: Target and modulator

Oral Oncology, 2015
Merkel cell carcinoma (MCC) is a aggressive skin cancer associated with the Merkel cell polyomavirus (MCPyV). Presence of tumor-infiltrating lymphocytes and immune competence are strongly correlated with the course of the disease. MCPyV encoded proteins should be highly effective targets for cytotoxic immune responses as they are both foreign to the ...
J.C. Becker, S.R. Hadrup, D. Schrama, C. Ritter   +3 more
openaire   +1 more source

Merkel cell polyomavirus (MCPyV) in chronic lymphocytic leukemia/small lymphocytic lymphoma

Leukemia Research, 2011
Merkel cell polyomavirus (MCPyV) is a novel polyomavirus that shows a strong association with Merkel cell carcinoma (MCC). Recent studies have demonstrated MCPyV in some cases of chronic lymphocytic leukemia/small lymphocytic lymphoma (CLL/SLL), a malignancy with a similar demographic as MCC.
Sheryl R Tripp, Sherrie L Perkins, Eric J Duncavage   +2 more
exaly   +3 more sources

Opening new roads for MCPyV

Blood, 2011
In this issue of Blood, Pancaldi et al report on the latent presence of large T antigen (LTag) sequences of the Merkel cell polyomavirus (MCPyV) in buffy coats of healthy individuals ...
openaire   +2 more sources

Prevalence of MCPyV in Merkel cell carcinoma and non‐MCC tumors

Journal of Cutaneous Pathology, 2009
Background: Merkel cell polyomavirus (MCPyV) is the likely causative agent of Merkel cell carcinoma (MCC). However, the prevalence of MCPyV in non‐MCC population and its possible role in the pathogenesis of other skin cancers are not known yet.Methods: A molecular pathology study was performed in 33 MCC samples and 33 age‐ and sex‐matched samples of ...
Christian, Andres, Benedetta, Belloni, Ursula, Puchta, Christian A, Sander, Michael J, Flaig   +4 more
openaire   +2 more sources

LT and SOX9 expression are associated with gene sets that distinguish Merkel cell polyomavirus (MCPyV)-positive and MCPyV-negative Merkel cell carcinoma

British Journal of Dermatology
Abstract Background Merkel cell carcinoma (MCC) is an aggressive malignant neuroendocrine tumour. There are two subsets of MCC, one related to Merkel cell polyomavirus (MCPyV) and the other to ultraviolet radiation (UVR).
Juan Torre-Castro, Marta Rodríguez, Ruth Alonso-Alonso, María Dolores Mendoza Cembranos, Jesús Frutos Díaz-Alejo, Marcos Rebollo-González, Jennifer Borregón, Laura Nájera Botello, Ignacio Mahillo-Fernández, Mathab Samimi, Thibault Kervarrec, Luis Requena, Miguel Ángel Piris   +12 more
openaire   +2 more sources