Results 61 to 70 of about 53,380 (247)

Transmission of Similar Mcr-1 Carrying Plasmids among Different Escherichia coli Lineages Isolated from Livestock and the Farmer

Antibiotics, 2021
Colistin use has mostly been stopped in human medicine, due to its toxicity. However, nowadays, it still is used as a last-resort antibiotic to treat hospital infections caused by multi-drug resistant Enterobacteriaceae.
Joaquim Viñes, Anna Cuscó, Sebastian Napp, Julio Alvarez, Jose Luis Saez-Llorente, Montserrat Rosàs-Rodoreda, Olga Francino, Lourdes Migura-Garcia   +7 more
doaj   +1 more source

Klebsiella pneumoniae Complex Harboring mcr-1, mcr-7, and mcr-8 Isolates from Slaughtered Pigs in Thailand

, 2021
Dissemination of the mobile colistin resistance gene mcr in Enterobacterales among humans, animals, and the environment is a public health issue. We characterized mcr genes in the Klebsiella pneumoniae complex (KpnC) isolated from slaughtered pigs in ...
Anusak Kerdsin, Parichart Boueroy, Nattamol Phetburom, Yukihiro Akeda, Peechanika Chopjitt, Rujirat Hatrongjit, Shigeyuki Hamada, Suphachai Nuanualsuwan   +7 more
core   +1 more source

An Antimicrobial, Cell‐Adhesive, and Growth Factor‐Producing Living Material Engineered From Bacillus subtilis Biofilms for Wound Healing

Advanced Healthcare Materials, EarlyView.
Bacillus subtilis is engineered to produce cell‐adhesive biofilms by functionalization of its biofilm scaffold protein TasA with a cell‐adhesion sequence. Living bacteria within the biofilm are also engineered to secrete growth factors and natively produce antimicrobial peptides (AMPs), resulting in a cell‐adhesive, antimicrobial, and growth factor ...
Mélanie Côté‐Cyr, Marie‐Jeanne Archambault, Caroline Dupuis, Steve Bourgault   +3 more
wiley   +1 more source

Functional domain analysis of MCR protein.

, 2013
(A) SDS-PAGE of purified MCR, MCR-N, and MCR-C proteins. (B) In vitro analysis of malonyl-CoA reductase activity. Enzyme activities were assayed as described in Materials and Methods.
Yamei Ding (461417), Guang Zhao (324536), Changshui Liu (461416), Qi Wang (22418), Mo Xian (186207)   +4 more
core   +1 more source

Resistance to Overdoping Allows Over 2000 S cm−1 Conductivity in P(g3BTTT) With Anion‐Exchange Doping

Advanced Materials, EarlyView.
Anion‐exchange doping of conjugated polymers is an effective way to achieve high conductivities. Here, we report over 2000 S cm−1 electrical conductivity for doped P(g3BTTT). In addition, we show that P(g3BTTT) sustains exceptionally high doping levels without any drop in the charge mobility.
Basil Hunger, Maximilian M. Horn, Eva Röck, Diego Rosas Villalva, Lize Bynens, Jochen Vanderspikken, Christina Kousseff, Silène Gobeil, Olivier Bardagot, Nesibe Akmanşen‐Kalayci, Sarah H. Tolbert, Iain McCulloch, Wouter Maes, Demetra Tsokkou, Natalie Banerji   +14 more
wiley   +1 more source

VIM-1-producing Enterobacter asburiae with mobile colistin resistance genes from wastewaters

BMC Genomics
Background Wastewaters are considered as important players in the spread of antimicrobial resistance, thus affecting the health of humans and animals. Here, we focused on wastewaters as a possible source of carbapenemase-producing Enterobacterales for ...
Iva Sukkar, Adam Valcek, Monika Dolejska
doaj   +1 more source

The global prevalence, formation, and evolutionary inference of bacteria co-carrying the blaNDM and mcr resistance genes

Frontiers in Microbiology
IntroductionThe global dissemination of bacteria harboring blaNDM and mcr genes, which confer co-resistance to carbapenem and polymyxin antibiotics, poses a catastrophic threat to public health due to the ineffectiveness of last-line antibiotics ...
Boqian Wang, Kexin Li, Kexin Li, Mingliang Chen, Mingliang Chen, Mingliang Chen, Jingjing Fu, Jingjing Fu, Rui Zhang, Rui Zhang, Rui Zhang, Wanqiu Liu, Wanqiu Liu, Yuxin Wang, Yuxin Wang, Zhixi Peng, Zhixi Peng, Aimaiti Buaijier, Aimaiti Buaijier, Aimaiti Buaijier, Xinru Zhao, Xinru Zhao, Xinru Zhao, Hongbin Song, Hongguang Ren, Xiaofeng Hu   +25 more
doaj   +1 more source

Colistin Resistance: Role of swine as reservoir of genes mcr-1, mcr-2, mcr-3, mcr-4 and mcr-5 in intensive production systems in Brazil

, 2021
A distribuição global de genes de resistência à colistina mediada por plasmídeos, como mcr-1, mcr-2, mcr-3, mcr-4 e mcr-5 representa uma preocupação para a saúde pública, uma vez que a colistina é utilizada como a última linha de defesa para o tratamento
Moreira, Jessica, Jessica Moreira
core   +1 more source

Vitamin C‐Induced Photo‐Redox Threshold Enables High‐Fidelity Volumetric Printing of Collagen

Advanced Materials, EarlyView.
Tomographic volumetric printing (TVP) of native proteins is limited by uncontrolled background crosslinking. Here, vitamin C is introduced as a biocompatible redox regulator to establish a tunable nonlinear polymerization threshold response for TVP.
Bin Wang, Amelia Hasenauer, Kristian Ivkovic, Ann‐Sophie Frind, David Fercher, Marcy Zenobi‐Wong   +5 more
wiley   +1 more source

Programmable Microgel Degradation in Dynamic Granular Hydrogels Guides Extracellular Matrix Assembly During Tissue Repair

Advanced Materials, EarlyView.
This study reports on the chemical modification of hyaluronic acid to create hydrogels with hydrolytic degradability ranging from 2–28 days. Granular hydrogels that undergo timed degradation to increase porosity enhance cell invasion and provisional ECM remodeling in a muscle injury model, leading to reduced fibrosis and improved regeneration ...
Zhiyuan Chen, Tuba Marjan, Xinyue Lu, Nicole E. Mertens, Keira Vesy, Dean E. Stornello, James F. Markworth, Taimoor H. Qazi   +7 more
wiley   +1 more source