Results 111 to 120 of about 1,079 (142)
Sialylation as a checkpoint for inflammatory and complement-related retinal diseases. [PDF]
Min Y +3 more
europepmc +1 more source
mCRP-Associated Vascular Pathophysiology in Progression and Outcome of Intracerebral Hemorrhage [PDF]
Monomeric C-reactive protein (mCRP), derived from the dissociation of the native pentameric CRP (pCRP), has been implicated in the pathophysiology of various neurological conditions, particularly intracerebral hemorrhage (ICH) and neurodegenerative diseases.
Mark Slevin, Slevin Mark
exaly +4 more sources
Monomeric C reactive protein (mCRP) regulates inflammatory responses in human and mouse chondrocytes [PDF]
C-reactive protein (CRP) is an acute-phase protein that is used as an established biomarker to follow disease severity and progression in a plethora of inflammatory diseases. However, its pathophysiologic mechanisms of action are still poorly defined and remain elusive. CRP, in its pentameric form, exhibits weak anti-inflammatory activity.
Ali Mobasheri +2 more
exaly +4 more sources
Sensor nodes consume their energy quickly due to their continuous perception, routing, and internal circuit mechanisms in Wireless Sensor Networks (WSNs). Especially, the nodes that are close to the sink node consume their energy more quickly, causing the hot spot problem.
Ebubekir Erdem, Sercan Yalcin
exaly +3 more sources
pCRP-mCRP Dissociation Mechanisms as Potential Targets for the Development of Small-Molecule Anti-Inflammatory Chemotherapeutics [PDF]
Circulating C-reactive protein (CRP) is a key acute-phase protein and one of the main clinical biomarkers for inflammation and infection. CRP is an important upstream mediator of inflammation and is associated with the onset of a number of important disease states including cardiovascular disease and neurodegenerative disorders such as Alzheimer's ...
Mario DI NAPOLI +2 more
exaly +9 more sources
mCRP triggers angiogenesis by inducing F3 transcription and TF signalling in microvascular endothelial cells [PDF]
SummaryInflammation contributes to vascular disease progression. However, the role of circulating inflammatory molecules on microvascular endothelial cell (mECs) is not fully elucidated. The aim of this study was to investigate the effects of the short pentraxin CRP on microvascular endothelial cell angiogenic function.
Gemma Arderiu +2 more
exaly +6 more sources
Monomeric C-reactive protein (mCRP) has recently been implicated in the abnormal vascular activation associated with development of atherosclerosis, but it may act more specifically through mechanisms perpetuating damaged vessel inflammation and subsequent aggregation and internalization of resident macrophages.
Doina Manu +2 more
exaly +4 more sources
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Molecular Immunology, 2003
Monoclonal antibodies (mAbs) are being increasingly used in cancer therapy owing to their ability to recognize specifically cancer cells and to activate complement- and cell-mediated cytotoxicity and/or to induce growth arrest or apoptosis. The therapeutic potential of anticancer antibodies is significantly limited due to the ability of cancer cells to
Z, Fishelson +4 more
openaire +2 more sources
Monoclonal antibodies (mAbs) are being increasingly used in cancer therapy owing to their ability to recognize specifically cancer cells and to activate complement- and cell-mediated cytotoxicity and/or to induce growth arrest or apoptosis. The therapeutic potential of anticancer antibodies is significantly limited due to the ability of cancer cells to
Z, Fishelson +4 more
openaire +2 more sources

