Results 181 to 190 of about 541,611 (331)

CircTspan3 Promotes Cartilage Development Through ANNEXIN A2‐Mediated Ferroptosis and Apoptosis Inhibition and Exosome‐Mediated Paracrine Signaling

Advanced Science, EarlyView.
This study reveals that XBP1s drives production of circTspan3, a circular RNA that strengthens cartilage by boosting anabolic activity and limiting cell death. Phosphorylated ANXA2 directs circTspan3 into exosomes, enabling paracrine repair. Exosomal circTspan3 expands growth‐plate cartilage and promotes in vivo regeneration, highlighting its promise ...
Yiming Pan, Fengmei Zhang, Jiayan Zhong, Qian Gong, Nana Geng, Biao Kuang, Qiumei Lan, Miao Yi, Qiqi Zeng, Cheng Chen, Mengtian Fan, Chunliang Zhao, Deping Zeng, Yu Du, Mao Nie, Zhibiao Wang, Fengjin Guo   +16 more
wiley   +1 more source

<i>Euphorbia bicolor</i> Xylene Extract Induces Mitochondrial and Endoplasmic Reticulum Stress-Mediated Apoptotic Pathways in MDA-MB-231 and T47D Cells. [PDF]

Int J Mol Sci
Rumpa MM, Ngo NL, Maier C.
europepmc   +1 more source

New-Onset MDA-5 Dermatomyositis in a Patient Following COVID-19 Vaccination: A Case Report

Eleana Bolla, G. Fragoulis, Alexios Iliopoulos   +2 more
openalex   +1 more source

Evaluation of known and novel inhibitors of Orai1-mediated store operated Ca2+ entry in MDA-MB-231 breast cancer cells using a Fluorescence Imaging Plate Reader assay

, 2016
Iman Azimi, Jack U. Flanagan, Ralph J. Stevenson, Marco Inserra, Irina Vetter, Gregory R. Monteith, William A. Denny   +6 more
openalex   +1 more source

EFFECTS OF OXIDANT SUBSTANCES ON ERYTHROCYTE DEFORMATlON:CHANGES INDUCED BY ISOURAMIL (ISO) AND MALONYLDEALDEHYDE (MDA) [PDF]

, 1985
O Pfafferott, E. Volger, M. Chevion, Paul Hochstein, Herbert J. Meiselman   +4 more
openalex   +1 more source

Astrocytic PCBP1 Suppresses Ferroptosis to Restore Glutamatergic Homeostasis and Mitigate Stress‐Induced Depression in Male Mice

Advanced Science, EarlyView.
This study demonstrates that polyC‐RNA‐binding protein 1 (PCBP1) in ventral hippocampal astrocytes modulates depressive‐like behaviors by regulating glutathione peroxidase 4‐mediated ferroptosis and synaptic glutamatergic transmission. PCBP1 overexpression intervention in the chronic unpredictable mild stress model rescues behavioral deficits ...
Jinyu Zhang, Binbin Zhao, Min Jia, Yan Zhao, Ye Lu, Wenyu Xi, Ziyu Zhu, Xiaojuan Gong, Qingyan Ma, Yuan Gao, Yijie Guo, Pan Li, Feng Zhu, Shuguang Wei, Xiancang Ma, Yunpeng Wang   +15 more
wiley   +1 more source

The pseudouridine synthase PUS7 is associated with stemness and represents a potential therapeutic target in triple-negative breast cancer cells. [PDF]

Sci Rep
Lu L, Xue L, Jiang S, He G, Deng X.
europepmc   +1 more source

Learned Conformational Space and Pharmacophore Into Molecular Foundational Model

Advanced Science, EarlyView.
The Ouroboros model introduces two orthogonal modules within a unified framework that independently learn molecular representations and generate chemical structures. This design enables flexible optimization strategies for each module and faithful structure reconstruction without prompts or noise.
Lin Wang, Yifan Wu, Hao Luo, Minglong Liang, Yihang Zhou, Cheng Chen, Chris Liu, Jun Zhang, Yang Zhang   +8 more
wiley   +1 more source

Efficient whole-genome sequencing of Monkeypox virus using a novel nuclease-multiple displacement amplification enrichment method. [PDF]

Npj Viruses
Misu M, Kurosu T, Yoshikawa T, Kawahara M, Oishi K, Shimojima M, Ebihara H.   +6 more
europepmc   +1 more source

MDA-BASED DEVELOPMENT OF DATA-DRIVEN WEB APPLICATIONS

, 2008
Attila Adamkó, Lajos Kollár
openalex   +1 more source