Results 31 to 40 of about 541,611 (331)

Toxic effects of sodium lauryl sulfate on antioxidant defense system and DNA damage in fish primary hepatocyte cultures

Macedonian Veterinary Review, 2022
Synthetic detergents which have a major role in environmental pollution accumulate over time and reach levels that harm nature. The surfactants which are abundantly used as cleaning components are discharged into the Van Lake with the sewage water. These
Aslı Ç. Yeltekin, Ahmet R. Oğuz
doaj   +1 more source

The role of miR-24 as a race related genetic factor in prostate cancer. [PDF]

, 2017
The incidence of prostate cancer (PCa) among African-Americans (AfA) is significantly higher than Caucasian-Americans (CaA) but the genetic basis for this disparity is not known.
Dahiya, Rajvir, Dasgupta, Pritha, Deng, Guoren, Hashimoto, Yutaka, Kato, Taku, Kulkarni, Priyanka, Kumar, Deepak, Majid, Shahana, Mitsui, Yozo, Saini, Sharanjot, Shahryari, Varahram, Shiina, Marisa, Sumida, Mitsuho, Tabatabai, Laura, Tanaka, Yuichiro, Yamamura, Soichiro   +15 more
core   +1 more source

Factors that affect Israeli paramedics’ decision to quit the profession: a mixed methods study

Israel Journal of Health Policy Research, 2019
Background The rate of Israeli paramedics leaving the profession has been increasing in recent years: 50% leave the profession in three years, for the most part before retirement.
Keren Dopelt, Oren Wacht, Refael Strugo, Rami Miller, Talma Kushnir   +4 more
doaj   +1 more source

The Serum Levels of Malondialdehyde, Vitamin E and Erythrocyte Catalase Activity in Psoriasis Patients [PDF]

Journal of Clinical and Diagnostic Research, 2014
Background: Psoriasis is a common skin disease which is characterized by increased epidermal proliferation and dermal inflammation affecting 0.1-3% of general population. Most of the psoriasis patients are young or middle aged adults, although no age
Vijaykumar M. Pujari, Shankargouda Ireddy, Inderraj Itagi, Siddesh Kumar H.   +3 more
doaj   +1 more source

Multilevel MDA-Lite Paris Traceroute

, 2018
Since its introduction in 2006-2007, Paris Traceroute and its Multipath Detection Algorithm (MDA) have been used to conduct well over a billion IP level multipath route traces from platforms such as M-Lab.
Fourmaux, Olivier, Friedman, Timur, Strowes, Stephen D., Vermeulen, Kevin   +3 more
core   +1 more source

PARP inhibitors elicit distinct transcriptional programs in homologous recombination competent castration‐resistant prostate cancer

Molecular Oncology, EarlyView.
PARP inhibitors are used to treat a small subset of prostate cancer patients. These studies reveal that PARP1 activity and expression are different between European American and African American prostate cancer tissue samples. Additionally, different PARP inhibitors cause unique and overlapping transcriptional changes, notably, p53 pathway upregulation.
Moriah L. Cunningham, Jasibel Vasquez‐Gonzalez, Samantha M. Barnada, Salome Tchotorlishvili, Latese Jones, Ryan Maguire, Genevieve Lewis, Kinza Rizwan, Jenny Deng, Salma Koachar, Drithi Patel, Hailey Shankle, Tessa Mulders, Namra Ajmal, Charalambos Solomides, Emad S. Alnemri, Teresa F. Alnemri, Ayesha A. Shafi, Leonard G. Gomella, Wm Kevin Kelly, Steven B. McMahon, Matthew J. Schiewer   +21 more
wiley   +1 more source

Mapping the patient journey of adult patients with Spinal Muscular Atrophy in Greece: key challenges and priorities for action

Orphanet Journal of Rare Diseases
Background Spinal Muscular Atrophy (SMA) carries a heavy burden for patients and caregivers, which, in Greece, is exacerbated by resource constraints and limited care integration.
Christina Golna, Chara Tzavara, Christiana Vasileiadi, Pavlos Golnas, Kornilia Binou, Antigone Karras, Kyriakos Souliotis   +6 more
doaj   +1 more source

Ethanol Extract of Marigold Flower (Tagetes Erecta L.) Decreases The Total Cholesterol, Low Density Lypoprotein (LDL), Malondialdehyde (MDA), and Apoliprotein B (APOB) on Hyperlipidemia Rat Models

Folia Medica Indonesiana, 2021
This study aimed to determine the effect of ethanol extract of gemitir flower (Tagetes erecta L.) on total cholesterol levels, Low-Density Lipoprotein C (LDL), Malondialdehyde (MDA), Apolipoprotein B (ApoB).
I Nyoman Bagus Aji Kresnapati, Siti Khaerunnisa, Indri Safitri   +2 more
doaj   +1 more source

Glucocorticoid receptor signalling activates YAP in breast cancer [PDF]

, 2017
The Hippo pathway is an oncosuppressor signalling cascade that plays a major role in the control of cell growth, tissue homoeostasis and organ size. Dysregulation of the Hippo pathway leads to aberrant activation of the transcription co-activator YAP ...
Bertolio, Rebecca, Bicciato, Silvio, Cappuzzello, Elisa, Del Sal, Giannino, Forcato, Mattia, Ingallina, Eleonora, Mano, Miguel, Marotta, Carolina, Neri, Carmelo, Rosato, Antonio, Ruggeri, Naomi, Sorrentino, Giovanni, Zannini, Alessandro   +12 more
core   +3 more sources

Cis‐regulatory and long noncoding RNA alterations in breast cancer – current insights, biomarker utility, and the critical need for functional validation

Molecular Oncology, EarlyView.
The noncoding region of the genome plays a key role in regulating gene expression, and mutations within these regions are capable of altering it. Researchers have identified multiple functional noncoding mutations associated with increased cancer risk in the genome of breast cancer patients.
Arnau Cuy Saqués, Aracele Martinez‐Mendez, John Crown, Alex Eustace   +3 more
wiley   +1 more source