Results 51 to 60 of about 737,646 (322)

The rice Aux/IAA transcription factor gene OsIAA18 enhances salt and osmotic tolerance in Arabidopsis

open access: yesBiologia Plantarum, 2020
In plants, auxin/indoleacetic acid (Aux/IAA) proteins are transcriptional regulators, which regulate developmental process and responses to phytohormones and stress treatments.
G. LI   +9 more
doaj   +1 more source

A Study Of Changes In The Lipid Profile, Malondialdehyd And Superoxide Desmutase In Normal Pregnancy [PDF]

open access: yesKirkuk Journal of Science, 2019
The study included (120) pregnancies during the months and the trimesters of pregnancy: first trimester, second trimester and third trimester conducted in Aljmhwry Republican hospital and Al- salaam Health center / Kirkuk with (20) (non-pregnant) women ...
Mozeiyan Namik   +2 more
doaj   +1 more source

The importance of patient compliance in repeated rounds of mass drug administration (MDA) for the elimination of intestinal helminth transmission

open access: yesParasites & Vectors, 2017
BackgroundSystematic non-compliance to chemotherapeutic treatment among a portion of the eligible population is thought to be a major obstacle to the elimination of helminth infections by mass drug administration (MDA).
Sam H. Farrell, J. Truscott, R. Anderson
semanticscholar   +1 more source

LDAcoop: Integrating non‐linear population dynamics into the analysis of clonogenic growth in vitro

open access: yesMolecular Oncology, EarlyView.
Limiting dilution assays (LDAs) quantify clonogenic growth by seeding serial dilutions of cells and scoring wells for colony formation. The fraction of negative wells is plotted against cells seeded and analyzed using the non‐linear modeling of LDAcoop.
Nikko Brix   +13 more
wiley   +1 more source

Gallic acid mitigates diclofenac-induced liver toxicity by modulating oxidative stress and suppressing IL-1β gene expression in male rats

open access: yesPharmaceutical Biology, 2020
Context Diclofenac (DIC) is an NSAID and consumption of this drug creates side effects such as liver injury. Gallic acid (GA), a natural component of many plants, is used as an antioxidant agent. Objective This study assesses the hepatoprotective effects
Mohsen Esmaeilzadeh   +6 more
doaj   +1 more source

Antioxidant and Hyperlipidemia Effect of Ganoderma Lucidum Fungus Alcoholic Extract in Male Albino Rats Using Tritonwr 1339 [PDF]

open access: yesKirkuk Journal of Science, 2019
The current study aimed at knowing the biological efficacy of Ganoderma lucidum mushroom extract anti-oxidation and induced hyperlipidemic using Triton WR1339 and comparing its efficacy with the simvastatin drug.
Husain AL- Obaidy   +2 more
doaj   +1 more source

Induction of G1-phase cell cycle arrest and apoptosis pathway in MDA-MB-231 human breast cancer cells by sulfated polysaccharide extracted from Laurencia papillosa

open access: yesCancer Cell International, 2016
Marine algae consumption is linked to law cancer incidences in countries that traditionally consume marine products. Hence, Phytochemicals are considered as potential chemo-preventive and chemotherapeutic agents against cancer.
Hossam Murad   +7 more
semanticscholar   +1 more source

TRAIL‐PEG‐Apt‐PLGA nanosystem as an aptamer‐targeted drug delivery system potential for triple‐negative breast cancer therapy using in vivo mouse model

open access: yesMolecular Oncology, EarlyView.
Aptamers are used both therapeutically and as targeting agents in cancer treatment. We developed an aptamer‐targeted PLGA–TRAIL nanosystem that exhibited superior therapeutic efficacy in NOD/SCID breast cancer models. This nanosystem represents a novel biotechnological drug candidate for suppressing resistance development in breast cancer.
Gulen Melike Demirbolat   +8 more
wiley   +1 more source

PARP inhibitor ABT-888 affects response of MDA-MB-231 cells to doxorubicin treatment, targeting Snail expression [PDF]

open access: yes, 2015
To overcome cancer cells resistance to pharmacological therapy, the development of new therapeutic approaches becomes urgent. For this purpose, the use of poly(ADP-ribose) polymerase (PARP) inhibitors in combination with other cytotoxic agents could ...
CAIAFA, Paola   +11 more
core   +6 more sources

Sesamin attenuates intestinal injury in sepsis via the HMGB1/TLR4/IL-33 signalling pathway

open access: yesPharmaceutical Biology, 2020
Context Sepsis is currently one of the leading causes of death in intensive care units (ICUs). Sesamin was previously reported to inhibit inflammation. However, no studies have revealed the impact of sesamin on sepsis.
Zhi-Ling Li   +5 more
doaj   +1 more source

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