Results 61 to 70 of about 8,365 (225)

Midkine Expression as a Candidate Biomarker to Predict the Recurrence of Stage IA Lung Adenocarcinoma

JTO Clinical and Research Reports
Background: Early recurrence limits the long-term survival of postoperative patients with stage IA lung adenocarcinoma (LUAD). This study aims to risk-stratify postoperative stage IA LUAD by means of the expression of Midkine (MDK). Materials and Methods:
Xiao Yang, PhD, Shuo Sun, BSc, Xunjie Kuang, BSc, Xianfeng Lu, MM, He Xiao, MM, Yi Duan, BSc, Yanli Xiong, MM, Di Zhang, BSc, Yu Xu, PhD, Jianwu Zhu, PhD, Mengxia Li, PhD   +10 more
doaj   +1 more source

Plasma midkine concentrations in healthy children, children with increased and decreased adiposity, and children with short stature.

PLoS ONE, 2019
BackgroundMidkine (MDK), one of the heparin-binding growth factors, is highly expressed in multiple organs during embryogenesis. Plasma concentrations have been reported to be elevated in patients with a variety of malignancies, in adults with obesity ...
Youn Hee Jee, Kun Song Lee, Shanna Yue, Ellen W Leschek, Matthew G Boden, Aysha Jadra, Anne Klibanski, Priya Vaidyanathan, Madhusmita Misra, Young Pyo Chang, Jack A Yanovski, Jeffrey Baron   +11 more
doaj   +1 more source

Prognostic value of midkine, syndecan-1, hyaluronan synthase-2, sestrin-1, laminin subunit alpha-4 and fibulin-3 for malignant pleural mesothelioma

Archives of Medical Science, 2021
Introduction The prognosis of malignant pleural mesothelioma (MPM) is poor, with a limited survival time. In this study, we aimed to examine expression levels of genes selected from relevant literature and to utilize in silico methods to determine genes ...
Hakan Akgun, Selma Metintas, Guntulu Ak, Secil Demirkol Canlı, Murat Isbilen, Ali O. Gure, Muzaffer Metintas   +6 more
doaj   +1 more source

Transendocardial injection of expanded autologous CD34+ cells after myocardial infarction: Design of the EXCELLENT trial

ESC Heart Failure, Volume 12, Issue 2, Page 1455-1463, April 2025.
Abstract Aims The extent of irreversible cardiomyocyte necrosis after acute myocardial infarction (AMI) is a major determinant of residual left ventricular (LV) function and clinical outcome. Cell therapy based on CD34+ cells has emerged as an option to help repair the myocardium and to improve outcomes.
Jerome Roncalli, François Roubille, Nicolas Meyer, Giulio Pompilio, Lionel Leroux, Philippe Henon, Guillaume Trebuchet, Anthony Criquet, Matthieu de Kalbermatten, Eric Saloux, Alain Manrique, Pierre‐Yves Marie, Deepak L. Bhatt, Scott D. Solomon, Gilles Montalescot, David E. Newby, Faiez Zannad, on behalf of the EXCELLENT Trial Investigators   +17 more
wiley   +1 more source

Autocrine and paracrine effects of MDK promote lymph node metastasis of cervical squamous cell carcinoma

iScience
Summary: Lymph node metastasis (LNM) is the main metastatic pathway of cervical cancer, which is closely related to 5-year survival rate of cervical squamous cell carcinoma (CSCC), yet the underlying mechanism remains unconfirmed.
He Fei, Tong Chen, Hua Jiang
doaj   +1 more source

Midkine Prevents Calcification of Aortic Valve Interstitial Cells via Intercellular Crosstalk

Frontiers in Cell and Developmental Biology, 2021
Calcified aortic valve disease (CAVD), the most common valvular heart disease, lacks pharmaceutical treatment options because its pathogenesis remains unclear.
Qian Zhou, Qian Zhou, Qian Zhou, Hong Cao, Xiaoyi Hang, Xiaoyi Hang, Xiaoyi Hang, Huamin Liang, Huamin Liang, Huamin Liang, Miaomiao Zhu, Miaomiao Zhu, Miaomiao Zhu, Yixian Fan, Yixian Fan, Yixian Fan, Jiawei Shi, Nianguo Dong, Ximiao He, Ximiao He, Ximiao He   +20 more
doaj   +1 more source

Proteomic signatures of equine dental tooth tissues in ageing and disease

Equine Veterinary Journal, EarlyView.
Abstract Background Ageing and dental disease in horses lead to structural and functional deterioration of dental tissues, yet their molecular signatures remain poorly characterised. Understanding how these processes alter the protein composition of enamel, dentin, cementum and pulp is essential for improving equine oral health and identifying ...
Anders Jensen, Danae Emilie Zambouli, Iris Gringel, Zoe Nugent, Kazuhiro Yamamoto, Lee Cooper, Andrew J. Peffers, Guido Rocchigiani, Mandy J. Peffers   +8 more
wiley   +1 more source

RESPON PETANI TERHADAP KEGIATAN MODEL DESA KONSERVASI (MDK) DI KAWASAN TAMAN BURU MASIGIT KAREUMBI

, 2017
Penelitian ini dilaksanakan dengan tujuan untuk mengetahui : (1) Respon petani terhadap kegiatan Model Desa Konservasi (MDK) Kawasan Taman Buru Masigit Kareumbi, (2) Kendala yang dihadapi dalam kegiatan Model Desa Konservasi (MDK) Kawasan Taman Buru ...
Soetoro Soetoro, Tito Hardiyanto, Mulpiadi, Mulpiadi, Mulpiadi Mulpiadi, Soetoro, Soetoro, Hardiyanto, Tito   +5 more
core   +1 more source

The German ONKOPEDIA Guideline for Myelofibrosis in 2025—Recommendations of an MPN Expert Panel of the German Society for Hematology and Oncology (DGHO)

International Journal of Cancer, EarlyView.
ABSTRACT The recently published ONKOPEDIA guideline on myelofibrosis, issued under the auspices of the German Society of Hematology and Oncology (DGHO), provides an updated, evidence‐based framework for the diagnosis and management of this rare, chronic myeloproliferative neoplasm.
Martin Griesshammer, Haifa Kathrin Al‐Ali, Gabriela M. Baerlocher, Konstanze Döhner, Steffen Koschmieder, Nicolaus Kröger, Petro E. Petrides, Dominik Wolf, Florian H. Heidel   +8 more
wiley   +1 more source

Zur Positionierung des MDK in der gesetzlichen Kranken- und Pflegeversicherung: Gutachten im Auftrag des AOK-Bundesverbandes

, 2016
Der Gesetzgeber hat seit der Gründung des MDK im Jahr 1988 – in Nachfolge zum vertrauensärztlichen Dienst – dessen Aufgabenprofil immer wieder modifiziert, sowohl im Bereich der Individualgutachten als auch im Bereich der Systemberatung der GKV.
Schmacke, Norbert
core   +1 more source