Results 41 to 50 of about 8,365 (225)

Amniotic fluid MDK concentrations.

open access: yes, 2016
Panel A: AF MDK concentrations (n = 202) declined with gestational age. Panel B: AF MDK concentrations were not significantly different between healthy term pregnancies in the absence of labor and during labor or between pregnancies complicated by PPROM ...
Gai Yan (2614453)   +7 more
core   +1 more source

The Growth Factor Midkine Antagonizes VEGF Signaling In Vitro and In Vivo

open access: yesNeoplasia: An International Journal for Oncology Research, 2008
Midkine (MDK) is a heparin-binding growth factor involved in growth, survival, migration, and differentiation of various target cells and dysregulation of MDK signaling is implicated in a variety of inflammatory diseases and cancers.
Edward Htun van der Horst   +8 more
doaj   +1 more source

Plasma midkine (MDK) concentrations in healthy children.

open access: yes, 2019
Plasma was obtained from healthy, non-obese children younger than 18 years (n = 222) from the United States or South Korea. Plasma midkine concentration was measured by sandwich enzyme-linked immunosorbent assay (ELISA).
Jack A. Yanovski (7542557)   +11 more
core   +1 more source

Midkine and Pleiotrophin Concentrations in Amniotic Fluid in Healthy and Complicated Pregnancies. [PDF]

open access: yesPLoS ONE, 2016
Midkine (MDK) and pleiotrophin (PTN) are heparin-binding growth factors that, in rodents, are highly expressed in early life and decrease to undetectable levels by adulthood.
Youn Hee Jee   +7 more
doaj   +1 more source

Assessment of Agro-Ecological Apple Replant Disease (ARD) Management Strategies: Organic Fertilisation and Inoculation with Mycorrhizal Fungi and Bacteria

open access: yesAgronomy, 2021
Apple replant disease (ARD) impacts the economic yield of orchards by physiological and morphological suppression of apple trees on replanted soils. The complexity of replant disease caused by a plethora of biological interactions and physical properties
Ulrike Cavael   +5 more
doaj   +1 more source

USP12 promotes breast cancer angiogenesis by maintaining midkine stability

open access: yesCell Death and Disease, 2021
Deubiquitinases (DUBs) have important biological functions, but their roles in breast cancer metastasis are not completely clear. In this study, through screening a series of DUBs related to breast cancer distant metastasis-free survival (DMFS) in the ...
Bin Sheng   +4 more
doaj   +1 more source

Midkine: A Cancer Biomarker Candidate and Innovative Therapeutic Approaches

open access: yesEuropean Journal of Breast Health
Midkine (MDK) is a protein that contributes to both physiological and pathological processes. Several studies provide insight into the different roles of MDK in development, tissue repair, neural plasticity, and health and disease processes.
Berna Yıldırım   +2 more
doaj   +1 more source

The Value of Serum Midkine Level in Diagnosis of Hepatocellular Carcinoma

open access: yesInternational Journal of Hepatology, 2015
Background and Aim. Identification of sensitive biomarkers to improve early diagnosis of HCC is needed. We aimed to evaluate serum midkine (MDK) as a biomarker for HCC diagnosis. Patients and Methods.
Karim Y. A. Shaheen   +3 more
doaj   +1 more source

Electroencephalographic Normalization as a Biomarker of Clinical Recovery in Down Syndrome Regression Disorder

open access: yesAnnals of Clinical and Translational Neurology, EarlyView.
ABSTRACT Objective Down syndrome regression disorder is a syndrome characterized by subacute loss of cognitive, behavioral, and functional abilities in individuals with Down syndrome. Electroencephalography abnormalities are frequently observed during evaluation, but it remains unclear whether these findings represent a dynamic marker of disease ...
Jonathan D. Santoro   +14 more
wiley   +1 more source

Heparin-stripping of MDK and PTN from amniotic fluid.

open access: yes, 2016
Assay specificity was assessed by removing both MDK and PTN from AF with heparin-Sepharose beads. ELISA signals for both MDK (Panel A) and PTN (Panel B) were abolished after treatment.
Gai Yan (2614453)   +7 more
core   +1 more source

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