Results 31 to 40 of about 8,365 (225)

Clinical relevance of double‐arm blood pressure measurement and prevalence of clinically important inter‐arm blood pressure differences in Indian Primary Care

The Journal of Clinical Hypertension, Accepted Article., 2022
Abstract Hypertension guidelines recommend measuring blood pressure (BP) in both arms at least once. However, this is seldom done due to uncertainties regarding measurement procedure and the implications of finding a clinically important inter‐arm BP difference (IAD).
Gurpreet S. Wander, Sinead T.J. McDonagh, M. Srinivasa Rao, R. Alagesan, JC Mohan, Ajit Bhagwat, AK Pancholia, M. Viswanathan, Manoj Bhavrilal Chopda, A Purnanand, PLN kapardhi, Arun R Vadavi, R Selvaraj, Pankaj Aneja, Suhas Hardas, Neil Bordoloi, N Sivakadaksham, Christopher E goswami, Christopher E Clark, Willem J. Verberk   +19 more
wiley   +1 more source

Midkine noncanonically suppresses AMPK activation through disrupting the LKB1-STRAD-Mo25 complex

Cell Death and Disease, 2022
Midkine (MDK), a secreted growth factor, regulates signal transduction and cancer progression by interacting with receptors, and it can be internalized into the cytoplasm by endocytosis. However, its intracellular function and signaling regulation remain
Tian Xia, Di Chen, Xiaolong Liu, Huan Qi, Wen Wang, Huan Chen, Ting Ling, Wuxiyar Otkur, Chen-Song Zhang, Jongchan Kim, Sheng-Cai Lin, Hai-long Piao   +11 more
doaj   +1 more source

Table_1_Targeting MDK Abrogates IFN-γ-Elicited Metastasis inCancers of Various Origins.docx

, 2022
IFN-γ is a pleiotropic cytokine with immunomodulatory and tumoricidal functions. It has been used as an anti-tumor agent in adjuvant therapies for various cancers.
Tao Wen (304736), Xichen Dong (12815672), Jian Liu (33711), Shibin Chen (6881042), Luyu Zheng (12815666), Qun Liu (67203), Lina Li (292076), Jingyu Tan (12815669), Ruijun Li (3247911), Changzhi Huang (577790)   +9 more
core   +1 more source

MOLECULAR EVALUATION OF MIDIKINE (MDK) AS A POTENTIAL BIOMARKER TODETECT HEPATOCELLULAR CARCINOMA [PDF]

Research Journal of Applied Biotechnology, 2018
The aim of this study was to assess the efficacy of non-invasive Midkineexpression level as diagnostic biomarkers of Hepatocellular Carcinoma and its relationship with diagnostic parameters.
Hisham Ismail, Ahmed Sharawy, Moustafa Sakr, Amira AbdelAziz   +3 more
doaj   +1 more source

The role of midkine in health and disease

Frontiers in Immunology, 2023
Midkine (MDK) is a neurotrophic growth factor highly expressed during embryogenesis with important functions related to growth, proliferation, survival, migration, angiogenesis, reproduction, and repair.
Emely Elisa Neumaier, Veit Rothhammer, Mathias Linnerbauer   +2 more
doaj   +1 more source

Image_1_Targeting MDK Abrogates IFN-γ-Elicited Metastasis inCancers of Various Origins.tif

, 2022
IFN-γ is a pleiotropic cytokine with immunomodulatory and tumoricidal functions. It has been used as an anti-tumor agent in adjuvant therapies for various cancers.
Tao Wen (304736), Xichen Dong (12815672), Jian Liu (33711), Shibin Chen (6881042), Luyu Zheng (12815666), Qun Liu (67203), Lina Li (292076), Jingyu Tan (12815669), Ruijun Li (3247911), Changzhi Huang (577790)   +9 more
core   +1 more source

Midkine Increases Diagnostic Yield in AFP Negative and NASH-Related Hepatocellular Carcinoma.

PLoS ONE, 2016
UnlabelledRobust biomarkers for population-level hepatocellular carcinoma (HCC) surveillance are lacking. We compared serum midkine (MDK), dickkopf-1 (DKK1), osteopontin (OPN) and AFP for HCC diagnosis in 86 HCC patients matched to 86 cirrhotics, 86 with
Roslyn Vongsuvanh, David van der Poorten, Tristan Iseli, Simone I Strasser, Geoffrey W McCaughan, Jacob George   +5 more
doaj   +1 more source

Pharmacokinetic (PK) and pharmacodynamic (PD) properties of MDK-703 in cynomolgus macaques.

, 2023
(A) PK of MDK-703: Animals (n = 3) were administered a single dose of 1 mg/kg MDK-703 via IV, SC, or IM. The serum concentration of MDK-703 at the indicated time points was determined by sandwich ELISA.
Angie Inkyung Park (17277210), Praechompoo Pongtornpipat (14918270), William J. Dower (17277207), Blake M. Williams (17277219), Ronald W. Barrett (17277231), Michael C. Needels (17277228), Prarthana Joshi (17277222), Alice V. Bakker (17277213), Steven E. Cwirla (17277216), Bryan A. Baxter (17277225)   +9 more
core   +1 more source

Wenn der MDK anfragt [PDF]

Klinische Monatsblätter für Augenheilkunde, 2013
Arbeitsunfahigkeit, Klinikabrechnung oder Pflegestufe – das alles und noch viel mehr begutachtet der Medizinische Dienst der Krankenversicherung (MDK). Dafur verlangt er auch Unterlagen von Arzten. Doch welche Informationen muss man herausgeben und wie lauft eine Prufung ab?
openaire   +2 more sources

Heterologous expression of the cryptic mdk gene cluster and structural revision of maduralactomycin A

, 2023
: After conducting an in silico analysis of the cryptic mdk cluster region and performing transcriptomic studies, an integrative Streptomyces BAC Vector containing the mdk gene sequence was constructed.
Br\uf6nstrup, Mark, Beemelmanns, Christine, Le, Hien T.N., Baunach, Martin, Um, Soohyun, Schwitalla, Jan W., Schalk, Felix   +6 more
core   +2 more sources