Results 81 to 90 of about 1,892 (112)
Single-cell and spatial transcriptomics integration reveals FAM49B promotes tumor-associated macrophages polarization in colorectal cancer via the MK pathway
Frontiers in ImmunologyObjectivesFAM49B has been shown to promote proliferation and metastasis of colorectal cancer (CRC) by stabilizing MYC through phosphorylation of NEK9; however, its role in shaping the immune suppressive tumor microenvironment (TME), particularly in ...Tianyu Liu, Quchen Ding, Jin Gou, Chen Lu, Xingming Lu, Jiatong Chen, Yiming E., Lianhong Li, Chongguo Zhang, Xiaojuan Zhu, Chunzhao Yu, Chunzhao Yu, Xiagang Luo +12 moredoaj +1 more sourceLipid-associated macrophages for osimertinib resistance and leptomeningeal metastases in NSCLC
Cell ReportsSummary: Leptomeningeal metastases (LMs) remain a devastating complication of non-small cell lung cancer (NSCLC), particularly following osimertinib resistance.Yang-Si Li, Wen-Pu Lai, Kai Yin, Mei-Mei Zheng, Hai-Yan Tu, Wei-Bang Guo, Liang Li, Shou-Heng Lin, Zhen Wang, Lu Zeng, Ben-Yuan Jiang, Zhi-Hong Chen, Qing Zhou, Xu-Chao Zhang, Jin-Ji Yang, Wen-Zhao Zhong, Xue-Ning Yang, Bin-Chao Wang, Yi Pan, Hua-Jun Chen, Fa-Man Xiao, Hao Sun, Yue-Li Sun, Xiao-Yan Bai, E.-E. Ke, Jia-Xin Lin, Si-Yang Maggie Liu, Yangqiu Li, Oscar Junhong Luo, Yi-Long Wu +29 moredoaj +1 more sourceSingle-cell RNA-sequencing atlas reveals an MDK-dependent immunosuppressive environment in ErbB pathway-mutated gallbladder cancer.
Journal of Hepatology, 2021 Yijian Zhang, Chunman Zuo, Liguo Liu, Yun-ping Hu, Boyi Yang, Shimei Qiu, Yang Li, Dongyan Cao, Zheng Ju, Jing Ge, Qiu Wang, Ting Wang, L. Bai, Yang Yang, Guoqiang Li, Z. Shao, Yuan Gao, Yongsheng Li, R. Bian, H. Miao, Lin Li, Xuechuan Li, Chengkai Jiang, Siyuan Yan, Ziyi Wang, Zeyu Wang, Xuya Cui, Wen Huang, Dongxi Xiang, Congjun Wang, Qiyun Li, Xiangsong Wu, W. Gong, Yun Liu, R. Shao, Fatao Liu, Maolan Li, Luonan Chen, Yingbin Liu +38 moresemanticscholar +1 more sourceSingle-cell and spatial dissection of necroptosis spatiotemporal evolution driving lymph node metastasis in gastric cancer
Cell Death DiscoveryLymph node metastasis is a common metastatic route of gastric cancer. However, the heterogeneity of tumor cells and tumor microenvironment between primary gastric cancer and metastatic lymph nodes, as well as the driving mechanisms of metastasis, remain ...Yuhua Hu, Feng Shen, Honghong Zhang, Zhuowen Long, Xiaojun Zhao, Jiale Wen, Yijian Sheng, Junxing Huang, Yan Chen, Qing Guo +9 moredoaj +1 more sourceSpatial and single-cell colocalisation analysis reveals MDK-mediated immunosuppressive environment with regulatory T cells in colorectal carcinogenesis
EBioMedicineM. Hashimoto, Yasuhiro Kojima, Takeharu Sakamoto, Yuki Ozato, Yusuke Nakano, Tadashi Abe, Kiyotaka Hosoda, Hideyuki Saito, Satoshi Higuchi, Y. Hisamatsu, T. Toshima, Yusuke Yonemura, Takaaki Masuda, Tsuyoshi Hata, Satoshi Nagayama, Koichi Kagawa, Yasuhiro Goto, Mitsuaki Utou, Ayako Gamachi, Kiyomi Imamura, Yuta Kuze, Junko Zenkoh, Ayako Suzuki, Kazuki K. Takahashi, A. Niida, Haruka Hirose, Shuto Hayashi, Jun Koseki, Satoshi Fukuchi, Kazunari Murakami, T. Yoshizumi, Kenji Kadomatsu, Taro Tobo, Yoshinao Oda, M. Uemura, H. Eguchi, Y. Doki, Masaki Mori, Masanobu Oshima, Tatsuhiro Shibata, Yutaka Suzuki, Teppei Shimamura, K. Mimori +42 moresemanticscholar +1 more sourceSynthesis and Characterization of a New Carbon-11 Labeled Positron Emission Tomography Radiotracer for Orexin 2 Receptors Neuroimaging
Drug Design, Development and TherapyYanli Wang,1 Yongle Wang,1,2 Yan Liu,1 Hua Cheng,1 Tewodros Mulugeta Dagnew,1 Yulong Xu,1 Changning Wang1 1Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology, Massachusetts General Hospital, Harvard Medical School, Charlestown ...Wang Y, Wang Y, Liu Y, Cheng H, Dagnew TM, Xu Y, Wang C +6 moredoaj DNA damage repair alterations modulate M2 polarization of microglia to remodel the tumor microenvironment via the p53-mediated MDK expression in glioma
EBioMedicine, 2019 Xiangqi Meng, Chunbin Duan, Hengyuan Pang, Qun Chen, Bo Han, Caijun Zha, Magafurov Dinislam, Pengfei Wu, Ziwei Li, Shi-hong Zhao, Ruijia Wang, Lin Lin, Chuanlu Jiang, Jinquan Cai +13 moresemanticscholar +1 more source
