Results 91 to 100 of about 15,040 (247)

Motives for MDMA Use: A Comparative Study with Alcohol and Cannabis

open access: yesEuropean Psychiatry
Introduction While research on drug use motives has primarily focused on widely used substances like alcohol, tobacco, and cannabis, understanding the motivations behind MDMA use is crucial for developing targeted therapeutic, preventive, and harm ...
D. Zullino   +6 more
doaj   +1 more source

The Australia story: Current status and future challenges for the clinical applications of psychedelics

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract The past decade has seen a huge increase in clinical research with psychedelic drugs and 3,4‐methylenedioxymethamphetamine (MDMA), which have revealed great potential for treating mental health conditions. Given this progress in research, as well as the current unmet clinical need of millions of patients, in 2023, the Australian Therapeutic ...
David J Nutt   +3 more
wiley   +1 more source

Pharmacogenomics of 3,4-Methylenedioxymethamphetamine (MDMA): A Narrative Review of the Literature

open access: yesPharmaceutics
3,4-Methylenedioxymethamphetamine (MDMA) is a synthetic amphetamine derivative with notable psychoactive properties and emerging therapeutic potential, particularly for treating post-traumatic stress disorders (PTSD) and substance use disorders. However,
Guillaume Drevin   +5 more
doaj   +1 more source

MDMA Impairs Response to Water Intake in Healthy Volunteers

open access: yesAdvances in Pharmacological Sciences, 2016
Hyponatremia is a serious complication of 3,4-methylenedioxymethamphetamine (MDMA) use. We investigated potential mechanisms in two double-blind, placebo-controlled studies.
Matthew J. Baggott   +6 more
doaj   +1 more source

Psychedelics, entactogens and psychoplastogens for depression and related disorders

open access: yesBritish Journal of Pharmacology, EarlyView.
Currently, the most actively investigated rapidly acting antidepressants, anxiolytics and/or anti PTSD agents, include psychedelics e.g. psilocybin, LSD, N,N‐dimethyltryptamine, ayahuasca; non‐hallucinogenic entactogens, e.g. MDMA; psychoplastogens which rapidly promote neuroplasticity, e.g.
Daniel Hoyer
wiley   +1 more source

Psychedelics as pharmacotherapeutics for substance use disorders: A scoping review on clinical trials and perspectives on underlying neurobiology

open access: yesBritish Journal of Pharmacology, EarlyView.
Theorized mechanism of dopamine homeostasis restoration in the nucleus accumbens core induced by a psychedelic intervention. Abstract Psychedelics have garnered great attention in recent years as treatments for major depressive disorder (MDD) and treatment‐resistant depression because of their ability to alter consciousness and afflicted cognitive ...
Lucas Wittenkeller   +3 more
wiley   +1 more source

Advice on MDMA in maize [PDF]

open access: yes, 2018
MDMA is the active ingredient of XTC. When drug waste containing MDMA was found in farmland and when NVWA discovered that maize on this farmland contained MDMA as well, the Office for Risk Assessment & Research (BuRO) investigated the risks of the ...
Office for Risk Assessment and Research, Netherlands Food and Consumer Product Safety Authority
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

open access: yesBritish Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus   +5 more
wiley   +1 more source

The Role of Religious Belief and Sentencing Decisions in a UK Sample

open access: yesJournal of Personality, EarlyView.
ABSTRACT Objective This is a stage 1 registered report submission that seeks to examine whether religious belief and a range of other individual differences variables are associated with youth justice preferences. Method As this is a stage 1 registered report, these are liable to change.
Isaac Halstead, Alex Lloyd
wiley   +1 more source

Exploring the Therapeutic Potential: A Systematic Review of 3,4-Methylenedioxymethamphetamine (MDMA) in the Management of Post-Traumatic Stress [paper]

open access: yes, 2023
This systematic review examines the current state of research on the use of 3,4-methylenedioxymethamphetamine (MDMA) as an adjunct to psychotherapy for the treatment of Post-Traumatic Stress Disorder (PTSD).
Hensley, Melissa
core  

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