Results 91 to 100 of about 18,018 (235)

MDMA /// Beyond ecstasy [PDF]

For nearly 40 years, MDMA has been used as a party drug in the Netherlands. Today, more than one in 10 people have used this prohibited substance at least once.
de Jonge, Martha, Kolthoff, Emile, Zandstra, Philippus, Toebes, Brigit; id_orcid, van den Brink, Wim, Gresnigt, Femke, Vermetten, Eric, De Cock, Ward   +7 more
core   +2 more sources

When psychedelic discourse meets local narrative: Selective uptake of psychedelic meanings surrounding mad honey in Nepal

Addiction, EarlyView.
Abstract Aims ‘Mad honey’ is produced when bees collect nectar from Rhododendron species containing grayanotoxins, naturally occurring diterpenoid toxins that can produce dose‐dependent intoxication. It has long been embedded in Nepalese medicinal and ritual practices but has recently become part of global psychedelic discourse. This study examined how
Sharon R. Sznitman, Surendra Tiwari
wiley   +1 more source

Predicting high‐risk novel benzodiazepines: A surveillance study of novel benzodiazepine detections and a case series of bromazolam exposures in New South Wales, Australia

Addiction, EarlyView.
Abstract Background and aims Novel benzodiazepines are increasingly detected in poisonings. Their relative toxicities remain poorly defined, complicating public health responses. Bromazolam has emerged in recent reports of severe poisoning. We sought a method to identify higher‐risk novel benzodiazepines, and to describe the clinical effects of ...
Emily Z. G. Sansoni, Janette L. Smith, Christine A. Harvey, Vanessa Shaw, Christopher Ewers, Ingrid Berling, Thanjira Jiranantakan, Jared Brown, Darren M. Roberts   +8 more
wiley   +1 more source

Relationships among performance on simulated tasks of decision-making, positive outcome expectancies for MDMA, and age of first MDMA use [PDF]

, 2005
The purpose of this study was to examine relationships among 3,4-methylendioxymethamphetamine (MDMA) use patterns and beliefs, the Gambling Task, the delay discounting task, and the Adult Self-Report (ASR). Sixty-eight college students completed measures
Patterson, Scott Michael, null null, Scott Patterson   +2 more
core   +1 more source

Pharmacogenomics of 3,4-Methylenedioxymethamphetamine (MDMA): A Narrative Review of the Literature

Pharmaceutics
3,4-Methylenedioxymethamphetamine (MDMA) is a synthetic amphetamine derivative with notable psychoactive properties and emerging therapeutic potential, particularly for treating post-traumatic stress disorders (PTSD) and substance use disorders. However,
Guillaume Drevin, Maria Pena-Martin, Aurélien Bauduin, Antoine Baudriller, Marie Briet, Chadi Abbara   +5 more
doaj   +1 more source

Impacts of decriminalization and its subsequent amendment on drug possession incidents and charges in British Columbia, Canada: Interrupted time series analyses (2013–2024)

Addiction, EarlyView.
Abstract Background and aims Decriminalization of personal possession of select illegal drugs was implemented in British Columbia, Canada, for a three‐year period starting 31 January 2023; however, following perceived increases in public drug use and disorder, an amendment introduced on 7 May 2024 rolled back key provisions.
Jürgen Rehm, Sami Aftab Abdul, Marcos Sanches, Cayley Russell, Farihah Ali, Sameer Imtiaz   +5 more
wiley   +1 more source

Mean (SD) MDMA/MDA concentrations (µg/L) in MDMA and the combined pindolol+MDMA condition.

, 2014
Mean (SD) MDMA/MDA concentrations (µg/L) in MDMA and the combined pindolol+MDMA condition.
Rafael de la Torre (125317), Isabel Dziobek (418517), Samanta Yubero-Lahoz (125301), Kim P. C. Kuypers (290936), Magi Farre (5659783), Wouter Van den Bos (5659786), Johannes G. Ramaekers (290937)   +6 more
core   +1 more source

Safety pharmacology of acute mescaline administration in healthy participants

British Journal of Clinical Pharmacology, EarlyView.
Aims Psychedelics, including mescaline, may serve as novel treatments for depression and anxiety. However, data is scarce on the safety of mescaline. Methods The present pooled analysis included two double‐blind, randomized, placebo‐controlled studies with a total of 48 participants and 96 mescaline administrations. Single oral‐dose administrations (n =
Aaron Klaiber, Mélusine Humbert‐Droz, Laura Ley, Yasmin Schmid, Matthias E. Liechti   +4 more
wiley   +1 more source

Pharmacodynamic interactions between MDMA and concomitants in MDMA tablets on extracellular dopamine and serotonin in the rat brain. [PDF]

, 2011
3,4-methylenedioxymethamphetamine (MDMA) is a psychoactive stimulant abused by young people as the recreational drug ecstasy. Other compounds, either deliberately added or present as byproducts, are often found in MDMA tablets and can unexpectedly ...
Rie Ikeda, Fuchigami, Yuki, Kuroda, Naotaka, Yuki Fuchigami, Wada, Mitsuhiro, Yoshiko Igari, Nakashima, Kenichiro, Ikeda, Rie, Kenichiro Nakashima, Igari, Yoshiko, Mitsuhiro Wada, Naotaka Kuroda   +11 more
core   +1 more source

Novel approaches for drug development against chronic primary pain: A systematic review

British Journal of Pharmacology, EarlyView.
Abstract Chronic primary pain (CPP) persisting for more than 3 months, associated with significant emotional distress without any known underlying cause, is an unmet medical need. Traditional or adjuvant analgesics do not provide satisfactory pain relief for a great proportion of these patients.
Valéria Tékus, Éva Borbély, Andreas Goebel, Ralf Baron, Zsófia Hajna, Zsuzsanna Helyes   +5 more
wiley   +1 more source