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The Background and Chemistry of MDMA

Journal of Psychoactive Drugs, 1986
(1986). The Background and Chemistry of MDMA. Journal of Psychoactive Drugs: Vol. 18, MDMA: Proceedings of the Conference, pp. 291-304.
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MDMA and the “Ecstasy Paradigm”

Journal of Psychoactive Drugs, 2014
For nearly 30 years, there has been a steady flow of research papers highlighting the dangers of MDMA and the implications for ecstasy users. After such a long time, it would be reasonable to expect that these dangers would be obvious due to the large number of ecstasy users.
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The effects of MDMA preexposure on MDMA-induced taste aversions

2023
Although changes in a drug's aversive effects may impact its abuse potential, little is known about factors that impact the aversive effects of MDMA. To that end, the present study used the conditioned taste aversion (CTA) preparation to assess how prior MDMA experience may affect the drug's aversive properties.
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Ecstasy (MDMA) dependence

Drug and Alcohol Dependence, 1999
Methylenedioxymethamphetamine (MDMA) is generally described as non-addictive. However, this report describes three cases in which criteria for dependence were met. A wider understanding that MDMA can be addictive in rare cases is important as very heavy use may cause lasting neuronal changes. This risk could be reduced with effective identification and
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Discriminative profile of MDMA

Pharmacology Biochemistry and Behavior, 1986
Groups of rats were trained to discriminate the stimulus properties of dopaminergically and/or serotonergically active drugs, viz., apomorphine, fenfluramine, tetrahydro-beta-carboline (THBC) and l-cathinone. Once trained, these animals were given several doses of drugs used in training and dose-response relationships and ED50 values were generated ...
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A Clinical Crossroads for MDMA

Journal of Psychoactive Drugs, 2005
Clinical studies of MDMA have been hindered by the fear of harming participants through MDMA-induced neurotoxicity. However, experimental animal studies and brain imaging studies of recreational Ecstasy users have not evidenced that a therapeutic dose of MDMA would be sufficient to cause long-term serotonergic deficits.
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MDMA in PTSD

2019
As just one of several psychotropics being examined for potential adjunctive use with psychotherapy, MDMA exhibited a very strong effect size at full dose relative to a small-dose “active control." It was used in two therapy sessions, 1 month apart, in addition to 18 hours of psychotherapy without MDMA–all of which was manual driven.
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MDMA

2008
Sandra Mcpherson, Errol Yudko
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MDMA Reconsidered

Journal of Psychoactive Drugs, 1986
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History of MDMA

1990
There can never be a complete history of any intensely controversial topic whose proponents and skeptics state their beliefs with equal confidence. Some historical facts will rest uncontested. Many facts will be clothed in opinions that will color the way the facts are to be interpreted. Other facts will never be publicly known, for reasons of legality
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