Results 71 to 80 of about 22,933 (184)

Contezolid in the Treatment of Multidrug‐Resistant Tuberculous Meningitis: A Case Report

Clinical Case Reports, Volume 14, Issue 6, June 2026.
ABSTRACT Multidrug‐resistant tuberculous meningitis (MDR‐TBM) has a high mortality rate, and treatment options are limited. Linezolid is recommended for refractory cases but often causes intolerable adverse reactions such as peripheral neuropathy. Contezolid, a novel oxazolidinone, has shown better safety profiles in preclinical and early clinical ...
Na Wang, Xingyu Li, Qiaoyi Yan, Haitao Su, Yufeng Liu, Yanhong Li, Chunrong Yang, Yingchun Gu, Taoli Yan, Qiuzhen Wang, Xia Liu   +10 more
wiley   +1 more source

Is HIV infection a risk factor for multi-drug resistant tuberculosis? A systematic review.

PLoS ONE, 2009
BackgroundTuberculosis (TB) is an important cause of human suffering and death. Human immunodeficiency virus (HIV), multi-drug resistant TB (MDR-TB), and extensive drug resistant tuberculosis (XDR-TB) have emerged as threats to TB control.
Sujit Suchindran, Emily S Brouwer, Annelies Van Rie   +2 more
doaj   +1 more source

High prevalence of primary multidrug resistant tuberculosis in persons with no known risk factors.

PLoS ONE, 2011
IntroductionIn high multidrug resistant (MDR) tuberculosis (TB) prevalence areas, drug susceptibility testing (DST) at diagnosis is recommended for patients with risk factors for MDR.
Larissa Otero, Fiorella Krapp, Cristina Tomatis, Carlos Zamudio, Francine Matthys, Eduardo Gotuzzo, Patrick Van der Stuyft, Carlos Seas   +7 more
doaj   +1 more source

Mitigating treatment failure of pulmonary pre-extensively drug-resistant tuberculosis: The role of new and repurposed drugs

Journal of Microbiology, Immunology and Infection
Background: Pre-extensively drug-resistant tuberculosis (pre-XDR-TB), defined as multidrug-resistant TB (MDR-TB) with additional resistance to any fluoroquinolone (FQ) is difficult to treat.
Yi-Wen Huang, Ming-Chih Yu, Chih-Bin Lin, Jen-Jyh Lee, Chou-Jui Lin, Shun-Tien Chien, Chih-Hsin Lee, Chen-Yuan Chiang   +7 more
doaj   +1 more source

Clinical Profiles of Multidrug-Resistant and Rifampicin-Monoresistant Tuberculosis in Korea, 2018–2021: A Nationwide Cross-Sectional Study [PDF]

Tuberculosis and Respiratory Diseases
Background This study aimed to identify the clinical characteristics of multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB) in the Republic of Korea. Methods Data of notified people with tuberculosis between July 2018 and December 2021 were
Jinsoo Min, Yousang Ko, Hyung Woo Kim, Hyeon-Kyoung Koo, Jee Youn Oh, Doosoo Jeon, Taehoon Lee, Young-Chul Kim, Sung Chul Lim, Sung Soon Lee, Jae Seuk Park, Ju Sang Kim   +11 more
doaj   +1 more source

Yield of facility-based verbal screening amongst household contacts of patients with multi-drug resistant tuberculosis in Pakistan

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2017
Background: Household contacts of multidrug-resistant tuberculosis (MDR-TB) patients are at a high risk of getting infected with TB/MDR-TB, therefore symptomatic or vulnerable individuals should be screened and treated early.
Ejaz Qadeer, Razia Fatima, Mahboob Ul Haq, Aashifa Yaqoob, Nang Thu Thu Kyaw, Safieh Shah, Mrinalini Das, Petros Isaakidis   +7 more
doaj   +1 more source

Multidrug-resistant tuberculosis and risk factors associated with its development: a retrospective study

Journal of Infection in Developing Countries, 2015
Introduction: Multidrug-resistant tuberculosis (MDR-TB) has emerged as a major clinical public health threat and challenges the national TB control program in Malaysia. Data that elaborates on the risk factors associated with the development of MDR-TB is
Omar Sald Elmi, Habsah Hasan, Sarimah Abdullah, Mat Zuki Mat Jeab, Zilfalil Bin Alwi, Nyi Nyi Naing   +5 more
doaj   +1 more source

Multidrug-Resistant Tuberculosis in Rural Eastern Cape, South Africa: Clinical, Bacteriological, and Programmatic Predictors of Poor Treatment Outcomes

Microorganisms
Drug-resistant tuberculosis (DR-TB), particularly multidrug-resistant TB (MDR-TB), remains a significant public health challenge in rural South Africa, where diagnostic and treatment infrastructure is limited.
Mbulelo Cebisa, Ntandazo Dlatu, Mojisola Clara Hosu, Teke Apalata, Lindiwe Modest Faye   +4 more
doaj   +1 more source

Clinical risk factors associated with multidrug-resistant tuberculosis (MDR-TB) in Mali

International Journal of Infectious Diseases, 2019
Background: MDR-TB is a major threat to global TB control. In 2015, 580,000 were treated for MDR-TB worldwide. The worldwide roll-out of GeneXpert MTB/RIF® has improved diagnosis of MDR-TB; however, in many countries laboratories are unable to assess ...
Bocar Baya, Chad J. Achenbach, Bourahima Kone, Yacouba Toloba, Djeneba K. Dabitao, Bassirou Diarra, Drissa Goita, Seydou Diabaté, Mamoudou Maiga, Dianguina Soumare, Khadidia Ouattara, Tenin Kanoute, Gaoussou Berthe, Youssouf M. Kamia, Yeya dit Sadio Sarro, Moumine Sanogo, Antieme C.G. Togo, Bindongo P.P. Dembele, Nadie Coulibaly, Amadou Kone, Maxwell Akanbi, Michael Belson, Sounkalo Dao, Susan Orsega, Sophia Siddiqui, Seydou Doumbia, Robert L. Murphy, Souleymane Diallo   +27 more
doaj   +1 more source

Prevalence of MDR TB in North Bihar

, 2023
Background: MDR tuberculosis (MDR TB) is a major public health concern in India, however there is a scarcity of data on the prevalence of MDR TB in the country. The objective of this study is to use a molecular diagnostic method to establish the prevalence of MDR TB in North Bihar and to facilitate early diagnosis and treatment.
openaire   +2 more sources