Results 91 to 100 of about 273,177 (229)

The Paediatric BCG Vaccine Century: From Historical Success to Future Innovations

Acta Paediatrica, Volume 115, Issue 11, Page 2433-2440, November 2026.
ABSTRACT Aim The tuberculosis (TB) vaccine, Bacille‐Calmette‐Guérin (BCG), protects infants against severe forms of primary TB. Yet, it does not protect against pulmonary reactivation TB in adults. Methods A literature review was conducted between 1st January and 28th February 2025 using PubMed, Google Scholar and reports of the World Health ...
Stefan H. E. Kaufmann
wiley   +1 more source

MDR-TB electronic medical records abstraction tool.

MDR-TB electronic medical records abstraction tool.
J. Christo Heunis (13046945), N. Gladys Kigozi (13046948), Ernest Peresu (13046942), Diana De Graeve (11642908)   +3 more
core   +1 more source

Chimeric IL‐6/4R‐LL37 Engineered Macrophages Achieve Synchronized Inflammation Control and Antimicrobial Defence in Sepsis

Advanced Science, Volume 13, Issue 60, 28 October 2026.
Engineered macrophages programmed in situ by LNP‐delivered IL‐6/4 fusion and LL37 mRNAs simultaneously dampen cytokine storm, promote M2‐like repair, and enhance direct bacterial killing in sepsis. This combinatorial strategy restores T cell and macrophage function, lowers organ bacterial burden, and improves survival, highlighting a precision, host ...
Tianyang Jie, Zheyu Zhang, Hao Zhang, Linke Bian, Penglong Zheng, Sijia Zhou, Minqi Wang, Mingyu Qu, Yufei Wang, Xinhua Qu, Bing Yue   +10 more
wiley   +1 more source

CD4 evolution over time in MDR-TB/HIV co-infected patients under ART and MDR-TB treatment, Mumbai, India.

, 2013
CD4 evolution over time in MDR-TB/HIV co-infected patients under ART and MDR-TB treatment, Mumbai, India.
Esdras Da Silva (316423), Helen S. Cox (80991), Bhanumati Varghese (316420), Petros Isaakidis (316418), Homa Mansoor (316421), Joanna Ladomirska (316422), Peter Saranchuk (272818), Emanuele Pontali (338435), Camilla Rodrigues (287811), Giovanni B. Migliori (139497), Giovanni Sotgiu (16787), Chiara Montaldo (338434), Tony Reid (56960)   +12 more
core   +1 more source

Metabolic pathway regulation in MDR-TB.

, 2021
(A) Unbiased pathway analysis using plasma HRM with C18 negative chromatography to compare the metabolome of persons with multidrug resistant (MDR)-TB (n = 85) to (A) asymptomatic controls without TB disease (n = 57) and (B) persons with drug susceptible
Dean P. Jones (180039), Ken H. Liu (5848607), Manoj Khadka (5848610), Thomas R. Ziegler (9155143), James C. M. Brust (11478771), Rafick-Pierre Sékaly (118474), Eric A. Ortlund (7352939), Henry M. Blumberg (7348961), Kristal Maner-Smith (11478765), Neel R. Gandhi (7292717), Russell R. Kempker (7348955), Ashish Sharma (319838), N. Sarita Shah (11478768), Jeffrey M. Collins (5753942), Brendan Prideaux (1604743), Nestani Tukvadze (333421)   +15 more
core   +1 more source

Is HIV infection a risk factor for multi-drug resistant tuberculosis? A systematic review.

PLoS ONE, 2009
BackgroundTuberculosis (TB) is an important cause of human suffering and death. Human immunodeficiency virus (HIV), multi-drug resistant TB (MDR-TB), and extensive drug resistant tuberculosis (XDR-TB) have emerged as threats to TB control.
Sujit Suchindran, Emily S Brouwer, Annelies Van Rie   +2 more
doaj   +1 more source

High prevalence of primary multidrug resistant tuberculosis in persons with no known risk factors.

PLoS ONE, 2011
IntroductionIn high multidrug resistant (MDR) tuberculosis (TB) prevalence areas, drug susceptibility testing (DST) at diagnosis is recommended for patients with risk factors for MDR.
Larissa Otero, Fiorella Krapp, Cristina Tomatis, Carlos Zamudio, Francine Matthys, Eduardo Gotuzzo, Patrick Van der Stuyft, Carlos Seas   +7 more
doaj   +1 more source

Epidemic Levels of Drug Resistant Tuberculosis (MDR and XDR-TB) in a High HIV Prevalence Setting in Khayelitsha, South Africa. [PDF]

, 2010
BACKGROUND: Although multidrug-resistant tuberculosis (MDR-TB) is emerging as a significant threat to tuberculosis control in high HIV prevalence countries such as South Africa, limited data is available on the burden of drug resistant tuberculosis and ...
McDermid, Cheryl, Coetzee, David, Goemaere Eric, Azevedo, Virginia, John Simpson, McDermid Cheryl, Coetzee, D, Barnard, M, David Coetzee, van Cutsem Gilles, Coetzee, G, Coetzee David, Cox, Helen S, Goemaere, Eric, Cox, H S, Simpson, J, Goemaere, E, Simpson, John, Odelia Muller, Eric Goemaere, Helen S. Cox, Muller Odelia, van Cutsem, Gilles, Simpson John, Gerrit Coetzee, Muller, O, Marinus Barnard, Cox Helen S., Muller, Odelia, Cheryl McDermid, Virginia Azevedo, Gilles van Cutsem, McDermid, C, Azevedo Virginia, van Cutsem, G, Coetzee Gerrit, Barnard, Marinus, Azevedo, V, Coetzee, Gerrit, Barnard Marinus, Helen S Cox   +40 more
core   +2 more sources

Faktor Risiko Tuberkulosis Multidrug Resistant (TB-MDR) [PDF]

, 2015
Tuberkulosis (TB) merupakan penyakit menular yang disebabkan oleh kuman Mycobacterium tuberculosis. TB masih merupakan masalah global kesehatan. Penyakit ini merupakan penyakit infeksi kedua yang menyebabkan kematian diseluruh dunia setelah penyakit ...
Syahrezki, Mohammad
core  

Mitigating treatment failure of pulmonary pre-extensively drug-resistant tuberculosis: The role of new and repurposed drugs

Journal of Microbiology, Immunology and Infection
Background: Pre-extensively drug-resistant tuberculosis (pre-XDR-TB), defined as multidrug-resistant TB (MDR-TB) with additional resistance to any fluoroquinolone (FQ) is difficult to treat.
Yi-Wen Huang, Ming-Chih Yu, Chih-Bin Lin, Jen-Jyh Lee, Chou-Jui Lin, Shun-Tien Chien, Chih-Hsin Lee, Chen-Yuan Chiang   +7 more
doaj   +1 more source