Results 91 to 100 of about 260,092 (192)

Clinical Profiles of Multidrug-Resistant and Rifampicin-Monoresistant Tuberculosis in Korea, 2018–2021: A Nationwide Cross-Sectional Study [PDF]

Tuberculosis and Respiratory Diseases
Background This study aimed to identify the clinical characteristics of multidrug-resistant/rifampicin-resistant tuberculosis (MDR/RR-TB) in the Republic of Korea. Methods Data of notified people with tuberculosis between July 2018 and December 2021 were
Jinsoo Min, Yousang Ko, Hyung Woo Kim, Hyeon-Kyoung Koo, Jee Youn Oh, Doosoo Jeon, Taehoon Lee, Young-Chul Kim, Sung Chul Lim, Sung Soon Lee, Jae Seuk Park, Ju Sang Kim   +11 more
doaj   +1 more source

Obstructive Jaundice due to a Periportal Tuberculous Mass Complicated by Anti‐Tuberculous Drug‐Induced Liver Injury: A Case Report From a Low‐Resource Setting

Clinical Case Reports, Volume 14, Issue 9, September 2026.
ABSTRACT Periportal tuberculous lymphadenitis with obstructive jaundice is rare and may mimic malignancy. We report a case of obstructive jaundice caused by a periportal tuberculous mass confirmed by fine‐needle aspiration and GeneXpert. Treatment was complicated by anti‐tuberculous drug‐induced liver injury.
Girma Deshimo Lema, Yemisrach Chanie, Mathewos Tesfaye Yanore, Segenet Bizuneh Mengistu, Amanuel Berhanu Kotisso, Dawit Zena, Saymen Tsegaye Gebreeyesus, Tadesse Mulusew Gared, Nebyu Samuel Chekol, Ebrahim Umer Muhammed   +9 more
wiley   +1 more source

Yield of facility-based verbal screening amongst household contacts of patients with multi-drug resistant tuberculosis in Pakistan

Journal of Clinical Tuberculosis and Other Mycobacterial Diseases, 2017
Background: Household contacts of multidrug-resistant tuberculosis (MDR-TB) patients are at a high risk of getting infected with TB/MDR-TB, therefore symptomatic or vulnerable individuals should be screened and treated early.
Ejaz Qadeer, Razia Fatima, Mahboob Ul Haq, Aashifa Yaqoob, Nang Thu Thu Kyaw, Safieh Shah, Mrinalini Das, Petros Isaakidis   +7 more
doaj   +1 more source

Tuberculosis in Sudan: A Comprehensive Narrative Review of Epidemiological Trends, Diagnosis, Drug Resistance, Challenges, and Data Gaps

Health Science Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background and Aims This narrative review aims to provide a comprehensive overview of tuberculosis (TB) in Sudan, focusing on prevalence, drug resistance patterns, and associated challenges while identifying knowledge gaps in scientific research and data needed for effective management.
Mohammad Azhar Kamal, Hisham N. Altayb, Shima M. Abdulgader, Ehssan Moglad   +3 more
wiley   +1 more source

Diagnosis of non-MDR-TB and MDR-TB and the development of acquired (treatment-associated) MDR-TB.

, 2012
Diagram showing the detection of non-MDR-TB and MDR-TB. Individuals with MDR-TB transition through a state in which they are treated with standard first-line (DOTS) therapy before the multidrug resistance of their strain is detected.
Dilshod Pulatov (117174), Aizhan Dooronbekova (117173), Natalia Vezhnina (117175), Douglas K. Owens (117176), Jeremy D. Goldhaber-Fiebert (117177), Daniel E. Winetsky (117169), Diana M. Negoescu (117170), Olga Almukhamedova (117172), Emilia H. DeMarchis (117171)   +8 more
core   +1 more source

Multidrug-Resistant Tuberculosis in Rural Eastern Cape, South Africa: Clinical, Bacteriological, and Programmatic Predictors of Poor Treatment Outcomes

Microorganisms
Drug-resistant tuberculosis (DR-TB), particularly multidrug-resistant TB (MDR-TB), remains a significant public health challenge in rural South Africa, where diagnostic and treatment infrastructure is limited.
Mbulelo Cebisa, Ntandazo Dlatu, Mojisola Clara Hosu, Teke Apalata, Lindiwe Modest Faye   +4 more
doaj   +1 more source

Multidrug-resistant tuberculosis and risk factors associated with its development: a retrospective study

Journal of Infection in Developing Countries, 2015
Introduction: Multidrug-resistant tuberculosis (MDR-TB) has emerged as a major clinical public health threat and challenges the national TB control program in Malaysia. Data that elaborates on the risk factors associated with the development of MDR-TB is
Omar Sald Elmi, Habsah Hasan, Sarimah Abdullah, Mat Zuki Mat Jeab, Zilfalil Bin Alwi, Nyi Nyi Naing   +5 more
doaj   +1 more source

Bioengineered Extracellular Vesicles Mitigate Neuroinflammation by Neutralizing Pneumolysin and Delaying Disease Onset in Experimental Pneumococcal Meningitis

Journal of Extracellular Vesicles, Volume 15, Issue 9, September 2026.
ABSTRACT Bacterial meningitis is a life‐threatening neurological disorder frequently caused by a Streptococcus pneumoniae (the pneumococcus) infection of the brain. Standard treatment consists of antibiotics to eliminate bacteria and dexamethasone to reduce inflammation.
Kristine Farmen, Doste R. Mamand, Miguel Tofiño‐Vian, Georgia Yfanti, Xiuming Liang, Houze Zhou, Vicky W. Q. Hou, Samir El Andaloussi, Oscar P. B. Wiklander, Federico Iovino   +9 more
wiley   +1 more source

FAKTOR-FAKTOR YANG BERHUBUNGAN DENGAN PERILAKU PASIEN TB MDR DALAM PENCEGAHAN PENULARAN TB MDR DI WILAYAH KERJA PUSKESMAS KOTA SEMARANG [PDF]

, 2018
Setiap tahun, penduduk Kota Semarang semakin meningkat. Hal ini menyebabkan terjadinya kepadatan penduduk sehingga penyakit sangat mudah berkembang biak khususnya penyakit TB.Pengobatan TB yang tidak tuntas menyebabkan terjadinya resisten terhadap obat ...
DEVI, ASNIA ULIYA
core   +1 more source

Semi‐Mechanistic Joint Population Pharmacokinetic Modeling of the Novel Antituberculosis Drug Sorfequiline and Its Metabolite M3 in Healthy Volunteers

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 9, September 2026.
ABSTRACTSorfequiline is a novel diarylquinoline in development for treatment of tuberculosis. In vitro data suggest metabolism via CYP3A4, carrying the potential for presystemic metabolism and drug–drug interactions. Its major metabolite, M3, is pharmacologically active.
Jose M. Calderin, Jerry Nedelman, David H. Salinger, Thanakorn Vongjarudech, Paolo Denti, Elin M. Svensson   +5 more
wiley   +1 more source